Constance Sobsey
Constance Sobsey
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HMDB: a knowledgebase for the human metabolome
DS Wishart, C Knox, AC Guo, R Eisner, N Young, B Gautam, DD Hau, ...
Nucleic acids research 37 (suppl_1), D603-D610, 2009
Targeted and untargeted proteomics approaches in biomarker development
CA Sobsey, S Ibrahim, VR Richard, V Gaspar, G Mitsa, V Lacasse, ...
Proteomics 20 (9), 1900029, 2020
Detailed Biophysical Characterization of the Acid-Induced PrPc to PrPβ Conversion Process
TC Bjorndahl, GP Zhou, X Liu, R Perez-Pineiro, V Semenchenko, ...
Biochemistry 50 (7), 1162-1173, 2011
Chicken Soup For The Teenage Soul II: 101 more stories of life, love and learning
J Canfield, K Kirberger, MV Hansen
Random House, 2011
Development and evaluation of a liquid chromatography–mass spectrometry method for rapid, accurate quantitation of malondialdehyde in human plasma
CA Sobsey, J Han, K Lin, W Swardfager, A Levitt, CH Borchers
Journal of Chromatography B 1029, 205-212, 2016
Systematic optimization of the iMALDI workflow for the robust and straightforward quantification of signaling proteins in cancer cells
BC Froehlich, R Popp, CA Sobsey, S Ibrahim, AM LeBlanc, Y Mohammed, ...
PROTEOMICS–Clinical Applications 14 (5), 2000034, 2020
Direct and precise measurement of bevacizumab levels in human plasma based on controlled methionine oxidation and multiple reaction monitoring
VP Gaspar, S Ibrahim, CA Sobsey, VR Richard, A Spatz, RP Zahedi, ...
ACS Pharmacology & Translational Science 3 (6), 1304-1309, 2020
A multiplexed, automated immuno-matrix assisted laser desorption/ionization mass spectrometry assay for simultaneous and precise quantitation of PTEN and p110α in cell lines …
BC Froehlich, R Popp, CA Sobsey, S Ibrahim, A LeBlanc, Y Mohammed, ...
Analyst 146 (21), 6566-6575, 2021
Immuno-MALDI-MS for Accurate Quantitation of Targeted Peptides from Volume-Restricted Samples
CA Sobsey, B Froehlich, G Batist, CH Borchers
Neuronal Cell Death: Methods and Protocols, 203-225, 2022
Protein quantitation assays for Akt, PI3K p110 alpha, and PTEN to assess PI3K pathway activity in tumor tissue
CA Sobsey, R Popp, S Ibrahim, BC Froehlich, A Aguilar-Mahecha, ...
MOLECULAR CANCER RESEARCH 18 (10), 51-52, 2020
Protein quantitation assays for AKT and PTEN to better understand sensitivity and resistance of breast cancer patients to treatment with AKT inhibitor capivasertib
S Ibrahim, CA Sobsey, R Popp, RP Zahedi, G Batist, CH Borchers
CANCER RESEARCH 80 (4), 2020
mTORC1-driven protein translation correlates with clinical benefit of capivasertib within a genetically preselected cohort of PIK3CA-altered tumours
CA Sobsey, BC Froehlich, G Mitsa, S Ibrahim, R Popp, RP Zahedi, ...
Cancer Research Communications, 2024
Measurement of CYP1A2 and CYP3A4 activity by a simplified Geneva cocktail approach in a cohort of free-living individuals: a pilot study
CA Sobsey, N Mady, VR Richard, A LeBlanc, T Zakharov, CH Borchers, ...
Frontiers in Pharmacology 15, 1232595, 2024
Quantifying protein expression and activity complements genetics to optimize the use of targeted therapies in precision oncology
C Sobsey
McGill University, 2023
The metabolomics of chronic stress
CA Sobsey
The Prionet Prion Protein and Plasmid Production Platform Facility (PrP5)
BP Suriyamongkol, A Abera, V Semenchenko, C Sobsey, DS Wishart
PRION 5, 87-88, 2011
Is the Prion Protein an Innate Immune Response Protein?
BN Ametaj, SM Dunn, TC Bjorndhal, F Saleem, R Perez-Pineiro, ...
PRION 5, 23-24, 2011
Conversion of Syrian Hamster Prion Protein to Beta Oligomer and Fibril Forms Under Physiological PH Conditions
VV Semenchenko, TC Bjorndahl, X Liu, GP Zhou, F Saleem, S Acharya, ...
PRION 4 (3), 123-123, 2010
Lipopolysaccharide Interacted with Prion Protein and Converted it into a beta-sheet-rich Isoform Resistant to Proteinase K
BN Ametaj, F Saleem, V Semenchenko, C Sobsey, DS Wishart
PRION 4 (3), 123-124, 2010
PPo1-15: Conversion of Syrian Hamster Prion Protein to Beta Oligomer and Fibril Forms Under Physiological PH Conditions
V Semenchenko, T Bjorndahl, X Liu, GP Zhou, F Saleem, S Acharya, ...
Prion 4 (3), 0
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