Principles governing the phase separation of multidomain proteins P Mohanty, U Kapoor, D Sundaravadivelu Devarajan, TM Phan, A Rizuan, ... Biochemistry 61 (22), 2443-2455, 2022 | 44 | 2022 |
A Zn‐dependent structural transition of SOD1 modulates its ability to undergo phase separation B Das, S Roychowdhury, P Mohanty, A Rizuan, J Chakraborty, J Mittal, ... The EMBO Journal 42 (2), e111185, 2023 | 17 | 2023 |
Deamidation disrupts native and transient contacts to weaken the interaction between UBC13 and RING-finger E3 ligases P Mohanty, R Agrata, BI Habibullah, A GS, R Das Elife 8, e49223, 2019 | 15 | 2019 |
A synergy between site-specific and transient interactions drives the phase separation of a disordered, low-complexity domain P Mohanty, J Shenoy, A Rizuan, JF Mercado-Ortiz, NL Fawzi, J Mittal Proceedings of the National Academy of Sciences 120 (34), e2305625120, 2023 | 13* | 2023 |
A complex network of interdomain interactions underlies the conformational ensemble of monomeric TDP‐43 and modulates its phase behavior P Mohanty, A Rizuan, YC Kim, NL Fawzi, J Mittal Protein Science, e4891, 2023 | 6 | 2023 |
Multiscale simulations reveal TDP-43 molecular-level interactions driving condensation HI Ingólfsson, A Rizuan, X Liu, P Mohanty, PCT Souza, SJ Marrink, ... Biophysical Journal 122 (22), 4370-4381, 2023 | 6 | 2023 |
NEDD8 Deamidation inhibits Cullin RING ligase dynamics P Mohanty, KS Chatterjee, R Das Frontiers in Immunology 12, 695331, 2021 | 6 | 2021 |
Challenges in studying the liquid-to-solid phase transitions of proteins using computer simulations B Szała-Mendyk, TM Phan, P Mohanty, J Mittal Current Opinion in Chemical Biology 75, 102333, 2023 | 3 | 2023 |
Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates X Yan, D Kuster, P Mohanty, J Nijssen, K Pombo-García, A Rizuan, ... bioRxiv, 2024.01. 23.576837, 2024 | 1 | 2024 |
Abstract 1415 Investigating the impact of polyglutamine expansion on the conformational dynamics of Huntingtin Exon 1 in monomeric and oligomeric states using state-of-the-art … P Mohanty, T Phan, J Mittal Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
Dynamic interdomain interactions in oligomeric and higher-order assemblies can modulate the intrinsic structural features of huntingtin exon 1 P Mohanty, TM Phan, J Mittal Biophysical Journal 123 (3), 26a-27a, 2024 | | 2024 |
RNA-binding tunes the conformational plasticity and intradomain stability of TDP-43 tandem RNA recognition motifs B Ozguney, P Mohanty, J Mittal bioRxiv, 2024.02. 25.581941, 2024 | | 2024 |
Specific residues and conformational plasticity define the substrate specificity of short-chain dehydrogenases/reductases L Qian, P Mohanty, A Jayaraman, J Mittal, X Zhu Journal of Biological Chemistry 300 (1), 2024 | | 2024 |
Bacterial deamidases modulate ubiquitin structure and dynamics to dysregulate ubiquitin signaling R Agrata, P Mohanty, A Ravichandran, S Kumari, N Varshney, A GS, ... bioRxiv, 2023.05. 22.541748, 2023 | | 2023 |
Inhibition of the Ubiquitin pathway by Glutamine Deamidation Insights from Molecular Dynamics simulations P Mohanty Mumbai, 0 | | |