| Hidden alternative structures of proline isomerase essential for catalysis JS Fraser, MW Clarkson, SC Degnan, R Erion, D Kern, T Alber Nature 462 (7273), 669-673, 2009 | 535 | 2009 |
| Role of structural plasticity in signal transduction by the cryptochrome blue-light photoreceptor CL Partch, MW Clarkson, S Özgür, AL Lee, A Sancar Biochemistry 44 (10), 3795-3805, 2005 | 229 | 2005 |
| Antiparallel EmrE exports drugs by exchanging between asymmetric structures EA Morrison, GT DeKoster, S Dutta, R Vafabakhsh, MW Clarkson, A Bahl, ... Nature 481 (7379), 45-50, 2011 | 221 | 2011 |
| Dynamic coupling and allosteric behavior in a nonallosteric protein MW Clarkson, SA Gilmore, MH Edgell, AL Lee Biochemistry 45 (25), 7693-7699, 2006 | 157 | 2006 |
| Transient non-native hydrogen bonds promote activation of a signaling protein AK Gardino, J Villali, A Kivenson, M Lei, CF Liu, P Steindel, ... Cell 139 (6), 1109-1118, 2009 | 133 | 2009 |
| Rescue of conformational dynamics in enzyme catalysis by directed evolution R Otten, L Liu, LR Kenner, MW Clarkson, D Mavor, DS Tawfik, D Kern, ... Nature communications 9 (1), 1-11, 2018 | 108 | 2018 |
| Long-range dynamic effects of point mutations propagate through side chains in the serine protease inhibitor eglin c MW Clarkson, AL Lee Biochemistry 43 (39), 12448-12458, 2004 | 100 | 2004 |
| Free energy landscape of activation in a signalling protein at atomic resolution F Pontiggia, DV Pachov, MW Clarkson, J Villali, MF Hagan, VS Pande, ... Nature communications 6 (1), 1-14, 2015 | 85 | 2015 |
| Selected contribution: HSP20 phosphorylation in nitroglycerin-and forskolin-induced sustained reductions in swine carotid media tone CM Rembold, M O'Connor, M Clarkson, RL Wardle, RA Murphy Journal of Applied Physiology 91 (3), 1460-1466, 2001 | 64 | 2001 |
| Dynamic activation and regulation of the mitogen-activated protein kinase p38 GS Kumar, MW Clarkson, MBA Kunze, D Granata, AJ Wand, ... Proceedings of the National Academy of Sciences 115 (18), 4655-4660, 2018 | 57 | 2018 |
| Mesodynamics in the SARS nucleocapsid measured by NMR field cycling MW Clarkson, M Lei, EZ Eisenmesser, W Labeikovsky, A Redfield, D Kern Journal of biomolecular NMR 45 (1), 217-225, 2009 | 40 | 2009 |
| Increased rigidity of eglin c at acidic pH: evidence from NMR spin relaxation and MD simulations H Hu, MW Clarkson, J Hermans, AL Lee Biochemistry 42 (47), 13856-13868, 2003 | 40 | 2003 |
| Dissecting the microscopic steps of the cyclophilin A enzymatic cycle on the biological HIV-1 capsid substrate by NMR DA Bosco, EZ Eisenmesser, MW Clarkson, M Wolf-Watz, W Labeikovsky, ... Journal of molecular biology 403 (5), 723-738, 2010 | 32 | 2010 |
| Evidence against the ‘YT coupling’mechanism of activation in the response regulator NtrC J Villali, F Pontiggia, MW Clarkson, MF Hagan, D Kern Journal of Molecular Biology, 2014 | 30 | 2014 |
| Solution structure of polymerase μ's BRCT domain reveals an element essential for its role in nonhomologous end joining EF DeRose, MW Clarkson, SA Gilmore, CJ Galban, A Tripathy, ... Biochemistry 46 (43), 12100-12110, 2007 | 30 | 2007 |
| Conserved conformational dynamics determine enzyme activity KR Torgeson, MW Clarkson, D Granata, K Lindorff-Larsen, R Page, ... Science advances 8 (31), eabo5546, 2022 | 26 | 2022 |
| Cooperative dynamics across distinct structural elements regulate PTP1B activity KR Torgeson, MW Clarkson, GS Kumar, R Page, W Peti Journal of Biological Chemistry 295 (40), 13829-13837, 2020 | 17 | 2020 |
| Structural Dynamics of the Activation of Elongation Factor 2 Kinase by Ca2+-Calmodulin N Will, K Lee, F Hajredini, DH Giles, RR Abzalimov, M Clarkson, ... Journal of molecular biology 430 (17), 2802-2821, 2018 | 17 | 2018 |
| Ligand Binding Reduces Conformational Flexibility in the Active Site of Tyrosine Phosphatase Related to Biofilm Formation A (TpbA) from< i> Pseudomonas aeruginosa</i> D Koveal, MW Clarkson, TK Wood, R Page, W Peti Journal of molecular biology, 2013 | 17 | 2013 |
| NMR Based SARS-CoV-2 Antibody Screening MV Schoenle, Y Li, M Yuan, MW Clarkson, IA Wilson, W Peti, R Page Journal of the American Chemical Society 143 (21), 7930-7934, 2021 | 11 | 2021 |
Andrew L LeeProfessor of Chemical Biology and Medicinal Chemistry, University of North Carolina at Chapel HillPotvrđena adresa e-pošte na unc.edu
