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Pauline Lukey
Pauline Lukey
Director, drug discovery and development
Verified email at target2treatment.com - Homepage
Title
Cited by
Cited by
Year
Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling
JC Betts, PT Lukey, LC Robb, RA McAdam, K Duncan
Molecular microbiology 43 (3), 717-731, 2002
16862002
Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study
RG Jenkins, JK Simpson, G Saini, JH Bentley, AM Russell, R Braybrooke, ...
The lancet Respiratory medicine 3 (6), 462-472, 2015
3052015
Distinct phases of blood gene expression pattern through tuberculosis treatment reflect modulation of the humoral immune response
JM Cliff, JS Lee, N Constantinou, JE Cho, TG Clark, K Ronacher, EC King, ...
The Journal of infectious diseases 207 (1), 18-29, 2013
2692013
An epithelial biomarker signature for idiopathic pulmonary fibrosis: an analysis from the multicentre PROFILE cohort study
TM Maher, E Oballa, JK Simpson, J Porte, A Habgood, WA Fahy, A Flynn, ...
The Lancet Respiratory Medicine 5 (12), 946-955, 2017
2252017
In Situ Detection of Mycobacterium tuberculosis Transcripts in Human Lung Granulomas Reveals Differential Gene Expression in Necrotic Lesions
G Fenhalls, L Stevens, L Moses, J Bezuidenhout, JC Betts, P Helden, ...
Infection and immunity 70 (11), 6330-6338, 2002
2212002
Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF
PF Mercer, HV Woodcock, JD Eley, M Platé, MG Sulikowski, ...
Thorax 71 (8), 701-711, 2016
2022016
Signature Gene Expression Profiles Discriminate between Isoniazid-, Thiolactomycin-, and Triclosan-Treated Mycobacterium tuberculosis
JC Betts, A McLaren, MG Lennon, FM Kelly, PT Lukey, SJ Blakemore, ...
Antimicrobial agents and chemotherapy 47 (9), 2903-2913, 2003
1822003
Gene-expression patterns in whole blood identify subjects at risk for recurrent tuberculosis
R Mistry, JM Cliff, CL Clayton, N Beyers, YS Mohamed, PA Wilson, ...
The Journal of infectious diseases 195 (3), 357-365, 2007
1792007
Daily home spirometry: an effective tool for detecting progression in idiopathic pulmonary fibrosis
AM Russell, H Adamali, PL Molyneaux, PT Lukey, RP Marshall, ...
American journal of respiratory and critical care medicine 194 (8), 989-997, 2016
1722016
Human CD8+ CTL specific for the mycobacterial major secreted antigen 85A
SM Smith, R Brookes, MR Klein, AS Malin, PT Lukey, AS King, GS Ogg, ...
The Journal of Immunology 165 (12), 7088-7095, 2000
1692000
In situ production of gamma interferon, interleukin-4, and tumor necrosis factor alpha mRNA in human lung tuberculous granulomas
G Fenhalls, A Wong, J Bezuidenhout, P Van Helden, P Bardin, PT Lukey
Infection and immunity 68 (5), 2827-2836, 2000
1592000
Characterization of a Mycobacterium tuberculosis H37Rv transposon library reveals insertions in 351 ORFs and mutants with altered virulence
RA McAdam, S Quan, DA Smith, S Bardarov, JC Betts, FC Cook, ...
Microbiology 148 (10), 2975-2986, 2002
1492002
Baseline sputum time to detection predicts month two culture conversion and relapse in non-HIV-infected patients
AC Hesseling, G Walzl, DA Enarson, NM Carroll, K Duncan, PT Lukey, ...
The international journal of tuberculosis and lung disease 14 (5), 560-570, 2010
1332010
HR‐pQCT measures of bone microarchitecture predict fracture: systematic review and meta‐analysis
N Mikolajewicz, N Bishop, AJ Burghardt, L Folkestad, A Hall, KM Kozloff, ...
Journal of Bone and Mineral Research 35 (3), 446-459, 2020
1272020
Expression, characterization and subcellular localization of the Mycobacterium tuberculosis PPE gene Rv1917c
SL Sampson, P Lukey, RM Warren, PD Van Helden, M Richardson, ...
Tuberculosis 81 (5-6), 305-317, 2001
1272001
Distribution of IFN‐γ, IL‐4 and TNF‐α protein and CD8 T cells producing IL‐12p40 mRNA in human lung tuberculous granulomas
G Fenhalls, L Stevens, J Bezuidenhout, GE Amphlett, K Duncan, P Bardin, ...
Immunology 105 (3), 325-335, 2002
1242002
A biological role for ascorbate in the selective neutralization of extracellular phagocyte‐derived oxidants
R Anderson, PT Lukey
Annals of the New York Academy of Sciences 498 (1), 229-247, 1987
1201987
A randomised, placebo-controlled study of omipalisib (PI3K/mTOR) in idiopathic pulmonary fibrosis
PT Lukey, SA Harrison, S Yang, Y Man, BF Holman, A Rashidnasab, ...
European Respiratory Journal 53 (3), 2019
1172019
An αv‐RGD integrin inhibitor toolbox: drug discovery insight, challenges and opportunities
RJD Hatley, SJF Macdonald, RJ Slack, J Le, SB Ludbrook, PT Lukey
Angewandte Chemie International Edition 57 (13), 3298-3321, 2018
1132018
Protein expression by a Beijing strain differs from that of another clinical isolate and Mycobacterium tuberculosis H37Rv
C Pheiffer, JC Betts, HR Flynn, PT Lukey, P van Helden
Microbiology 151 (4), 1139-1150, 2005
1002005
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