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Eric Bachelder
Eric Bachelder
Associate Professor of Pharmacy, University of North Carolina
Potvrđena adresa e-pošte na email.unc.edu - Početna stranica
Naslov
Citirano
Citirano
Godina
Acetal-derivatized dextran: an acid-responsive biodegradable material for therapeutic applications
EM Bachelder, TT Beaudette, KE Broaders, J Dashe, JMJ Fréchet
Journal of the American Chemical Society 130 (32), 10494-10495, 2008
5012008
Acetalated dextran is a chemically and biologically tunable material for particulate immunotherapy
KE Broaders, JA Cohen, TT Beaudette, EM Bachelder, JMJ Fréchet
Proceedings of the National Academy of Sciences 106 (14), 5497-5502, 2009
3172009
Fully acid-degradable biocompatible polyacetal microparticles for drug delivery
SE Paramonov, EM Bachelder, TT Beaudette, SM Standley, CC Lee, ...
Bioconjugate Chemistry 19 (4), 911-919, 2008
2272008
A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1–insensitive models of triple-negative breast cancer
N Cheng, R Watkins-Schulz, RD Junkins, CN David, BM Johnson, ...
JCI insight 3 (22), 2018
2092018
'Educated'dendritic cells act as messengers from memory to naive T helper cells
O Alpan, E Bachelder, E Isil, H Arnheiter, P Matzinger
Nature immunology 5 (6), 615-622, 2004
1782004
In vitro analysis of acetalated dextran microparticles as a potent delivery platform for vaccine adjuvants
EM Bachelder, TT Beaudette, KE Broaders, JMJ Fréchet, MT Albrecht, ...
Molecular pharmaceutics 7 (3), 826-835, 2010
1582010
Acetalated dextran: a tunable and acid-labile biopolymer with facile synthesis and a range of applications
EM Bachelder, EN Pino, KM Ainslie
Chemical reviews 117 (3), 1915-1926, 2017
1402017
A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination
RD Junkins, MD Gallovic, BM Johnson, MA Collier, R Watkins-Schulz, ...
Journal of Controlled Release 270, 1-13, 2018
1322018
Acetal-modified dextran microparticles with controlled degradation kinetics and surface functionality for gene delivery in phagocytic and non-phagocytic cells
JA Cohen, TT Beaudette, JL Cohen, KE Broaders, EM Bachelder, ...
Advanced materials (Deerfield Beach, Fla.) 22 (32), 3593, 2010
1192010
TLR2 synergizes with both TLR4 and TLR9 for induction of the MyD88-dependent splenic cytokine and chemokine response to Streptococcus pneumoniae
KS Lee, CA Scanga, EM Bachelder, Q Chen, CM Snapper
Cellular immunology 245 (2), 103-110, 2007
1122007
Synthesis and characterization of acetalated dextran polymer and microparticles with ethanol as a degradation product
KJ Kauffman, C Do, S Sharma, MD Gallovic, EM Bachelder, KM Ainslie
ACS applied materials & interfaces 4 (8), 4149-4155, 2012
992012
Electrospray encapsulation of toll-like receptor agonist resiquimod in polymer microparticles for the treatment of visceral leishmaniasis
AD Duong, S Sharma, KJ Peine, G Gupta, AR Satoskar, EM Bachelder, ...
Molecular pharmaceutics 10 (3), 1045-1055, 2013
952013
In Vivo Studies on the Effect of Co-Encapsulation of CpG DNA and Antigen in Acid-Degradable Microparticle Vaccines
TT Beaudette, EM Bachelder, JA Cohen, AC Obermeyer, KE Broaders, ...
Molecular pharmaceutics 6 (4), 1160-1169, 2009
952009
T-Cell Activation by Antigen-Loaded pH-Sensitive Hydrogel Particles in Vivo: The Effect of Particle Size
JA Cohen, TT Beaudette, WW Tseng, EM Bachelder, I Mende, ...
Bioconjugate chemistry 20 (1), 111-119, 2009
902009
Vaccine formulations in clinical development for the prevention of severe acute respiratory syndrome coronavirus 2 infection
CJ Batty, MT Heise, EM Bachelder, KM Ainslie
Advanced drug delivery reviews 169, 168-189, 2021
882021
Synthesis, optimization, and characterization of camptothecin-loaded acetalated dextran porous microparticles for pulmonary delivery
SA Meenach, YJ Kim, KJ Kauffman, N Kanthamneni, EM Bachelder, ...
Molecular pharmaceutics 9 (2), 290-298, 2012
852012
Electrospray for generation of drug delivery and vaccine particles applied in vitro and in vivo
RT Steipel, MD Gallovic, CJ Batty, EM Bachelder, KM Ainslie
Materials Science and Engineering: C 105, 110070, 2019
832019
Microfabricated Devices for Enhanced Bioadhesive Drug Delivery: Attachment to and Small‐Molecule Release Through a Cell Monolayer Under Flow
KM Ainslie, RD Lowe, TT Beaudette, L Petty, EM Bachelder, TA Desai
Small 5 (24), 2857-2863, 2009
822009
Optimization of rapamycin-loaded acetalated dextran microparticles for immunosuppression
KJ Kauffman, N Kanthamneni, SA Meenach, BC Pierson, EM Bachelder, ...
International journal of pharmaceutics 422 (1-2), 356-363, 2012
792012
Acetalated dextran microparticles for codelivery of STING and TLR7/8 agonists
MA Collier, RD Junkins, MD Gallovic, BM Johnson, MM Johnson, ...
Molecular pharmaceutics 15 (11), 4933-4946, 2018
762018
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