Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly ER Horton, A Byron, JA Askari, DHJ Ng, A Millon-Frémillon, J Robertson, ... Nature cell biology 17 (12), 1577-1587, 2015 | 559 | 2015 |
Linking integrin conformation to function JA Askari, PA Buckley, AP Mould, MJ Humphries Journal of cell science 122 (2), 165-170, 2009 | 428 | 2009 |
Integrin-specific signaling pathways controlling focal adhesion formation and cell migration Z Mostafavi-Pour, JA Askari, SJ Parkinson, PJ Parker, TTC Ng, ... The Journal of cell biology 161 (1), 155-167, 2003 | 280 | 2003 |
Signal transduction via integrin adhesion complexes JD Humphries, MR Chastney, JA Askari, MJ Humphries Current opinion in cell biology 56, 14-21, 2019 | 264 | 2019 |
Crystal structure of a heparin‐and integrin‐binding segment of human fibronectin A Sharma, JA Askari, MJ Humphries, EY Jones, DI Stuart The EMBO journal, 1999 | 253 | 1999 |
SHARPIN is an endogenous inhibitor of β1-integrin activation JK Rantala, J Pouwels, T Pellinen, S Veltel, P Laasola, E Mattila, ... Nature cell biology 13 (11), 1315-1324, 2011 | 239 | 2011 |
The integrin adhesome network at a glance ER Horton, JD Humphries, J James, MC Jones, JA Askari, MJ Humphries Journal of cell science 129 (22), 4159-4163, 2016 | 231 | 2016 |
Defining the topology of integrin α5β1-fibronectin interactions using inhibitory anti-α5 and anti-β1 monoclonal antibodies: Evidence that the synergy sequence of fibronectin is … AP Mould, JA Askari, S Aota, KM Yamada, A Irie, Y Takada, HJ Mardon, ... Journal of Biological Chemistry 272 (28), 17283-17292, 1997 | 215 | 1997 |
Anti-integrin monoclonal antibodies A Byron, JD Humphries, JA Askari, SE Craig, AP Mould, MJ Humphries Journal of cell science 122 (22), 4009-4011, 2009 | 214 | 2009 |
Identification of a novel anti‐integrin monoclonal antibody that recognises a ligand‐induced binding site epitope on the β1 subunit AP Mould, AN Garratt, JA Askari, SK Akiyama, MJ Humphries FEBS letters 363 (1-2), 118-122, 1995 | 199 | 1995 |
A specific α5β1-integrin conformation promotes directional integrin translocation and fibronectin matrix formation K Clark, R Pankov, MA Travis, JA Askari, AP Mould, SE Craig, P Newham, ... Journal of cell science 118 (2), 291-300, 2005 | 162 | 2005 |
Conformational Changes in the Integrin औA Domain Provide a Mechanism for Signal Transduction via Hybrid Domain Movement AP Mould, SJ Barton, JA Askari, PA McEwan, PA Buckley, SE Craig, ... Journal of Biological Chemistry 278 (19), 17028-17035, 2003 | 162 | 2003 |
Integrin activation involves a conformational change in the α1 helix of the β subunit A-domain AP Mould, JA Askari, S Barton, AD Kline, PA McEwan, SE Craig, ... Journal of Biological Chemistry 277 (22), 19800-19805, 2002 | 161 | 2002 |
Integrin alpha 4 beta 1-mediated melanoma cell adhesion and migration on vascular cell adhesion molecule-1 (VCAM-1) and the alternatively spliced IIICS region of fibronectin. AP Mould, JA Askari, SE Craig, AN Garratt, J Clements, MJ Humphries Journal of Biological Chemistry 269 (44), 27224-27230, 1994 | 161 | 1994 |
Focal adhesions are sites of integrin extension JA Askari, CJ Tynan, SED Webb, ML Martin-Fernandez, C Ballestrem, ... Journal of cell biology 188 (6), 891-903, 2010 | 140 | 2010 |
Molecular basis of ligand recognition by integrin α5β1: I. Specificity of ligand binding is determined by amino acid sequences in the second and third NH2-terminal repeats of … AP Mould, JA Askari, MJ Humphries Journal of Biological Chemistry 275 (27), 20324-20336, 2000 | 137 | 2000 |
Role of ADMIDAS cation-binding site in ligand recognition by integrin α5β1 AP Mould, SJ Barton, JA Askari, SE Craig, MJ Humphries Journal of Biological Chemistry 278 (51), 51622-51629, 2003 | 130 | 2003 |
Reticular adhesions are a distinct class of cell-matrix adhesions that mediate attachment during mitosis JG Lock, MC Jones, JA Askari, X Gong, A Oddone, H Olofsson, ... Nature cell biology 20 (11), 1290-1302, 2018 | 128 | 2018 |
Cell adhesion is regulated by CDK1 during the cell cycle MC Jones, JA Askari, JD Humphries, MJ Humphries Journal of Cell Biology 217 (9), 3203-3218, 2018 | 127 | 2018 |
Divalent cations regulate the folding and activation status of integrins during their intracellular trafficking S Tiwari, JA Askari, MJ Humphries, NJ Bulleid Journal of cell science 124 (10), 1672-1680, 2011 | 124 | 2011 |