Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics Y Yang, J Kitagaki, RM Dai, YC Tsai, KL Lorick, RL Ludwig, SA Pierre, ... Cancer research 67 (19), 9472-9481, 2007 | 518 | 2007 |
The review of natural products: the most complete source of natural product information. A DerMarderosian, JA Beutler | 398 | 2002 |
Natural products as a foundation for drug discovery JA Beutler Current protocols in pharmacology 46 (1), 9.11. 1-9.11. 21, 2009 | 337 | 2009 |
Salicylihalamides A and B, Novel Cytotoxic Macrolides from the Marine Sponge Haliclona sp. KL Erickson, JA Beutler, JH Cardellina, MR Boyd The Journal of organic chemistry 62 (23), 8188-8192, 1997 | 282 | 1997 |
Englerin A, a Selective Inhibitor of Renal Cancer Cell Growth, from Phyllanthus engleri R Ratnayake, D Covell, TT Ransom, KR Gustafson, JA Beutler Organic letters 11 (1), 57-60, 2009 | 279 | 2009 |
Discovery of a novel antitumor benzolactone enamide class that selectively inhibits mammalian vacuolar-type (H+)-atpases MR Boyd, C Farina, P Belfiore, S Gagliardi, JW Kim, Y Hayakawa, ... Journal of pharmacology and experimental therapeutics 297 (1), 114-120, 2001 | 234 | 2001 |
Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones SR Budihas, I Gorshkova, S Gaidamakov, A Wamiru, MK Bona, ... Nucleic acids research 33 (4), 1249-1256, 2005 | 231 | 2005 |
Cholestane glycosides with potent cytostatic activities on various tumor cells from Ornithogalum saundersiae bulbs Y Mimaki, M Kuroda, A Kameyama, Y Sashida, T Hirano, K Oka, ... Bioorganic & Medicinal Chemistry Letters 7 (5), 633-636, 1997 | 225 | 1997 |
The large-scale isolation of bryostatin 1 from Bugula neritina following current good manufacturing practices DE Schaufelberger, MP Koleck, JA Beutler, AM Vatakis, AB Alvarado, ... Journal of natural products 54 (5), 1265-1270, 1991 | 203 | 1991 |
Cytotoxic Geranyl Stilbenes from Macaranga schweinfurthii JA Beutler, RH Shoemaker, T Johnson, MR Boyd Journal of natural products 61 (12), 1509-1512, 1998 | 177 | 1998 |
Structure− activity requirements for flavone cytotoxicity and binding to tubulin JA Beutler, E Hamel, AJ Vlietinck, A Haemers, P Rajan, JN Roitman, ... Journal of medicinal chemistry 41 (13), 2333-2338, 1998 | 173 | 1998 |
Securinine alkaloids: a new class of GABA receptor antagonist JA Beutler, EW Karbon, AN Brubaker, R Malik, DR Curtis, SJ Enna Brain Research 330 (1), 135-140, 1985 | 152 | 1985 |
1H- and 13C-nmr Assignments for Taxol, 7-epi-Taxol, and Cephalomannine GN Chmurny, BD Hilton, S Brobst, SA Look, KM Witherup, JA Beutler Journal of natural products 55 (4), 414-423, 1992 | 146 | 1992 |
A fluorescence-based high-throughput screening assay for inhibitors of human immunodeficiency virus-1 reverse transcriptase-associated ribonuclease H activity MA Parniak, KL Min, SR Budihas, SFJ Le Grice, JA Beutler Analytical biochemistry 322 (1), 33-39, 2003 | 138 | 2003 |
Matching the power of high throughput screening to the chemical diversity of natural products CJ Henrich, JA Beutler Natural product reports 30 (10), 1284-1298, 2013 | 132 | 2013 |
Tannic acid is an inhibitor of CXCL12 (SDF-1α)/CXCR4 with antiangiogenic activity X Chen, JA Beutler, TG McCloud, A Loehfelm, L Yang, HF Dong, ... Clinical Cancer Research 9 (8), 3115-3123, 2003 | 131 | 2003 |
A chemical screening strategy for the dereplication and prioritization of HIV-inhibitory aqueous natural products extracts JH Cardellina, MHG Munro, RW Fuller, KP Manfredi, TC McKee, ... Journal of natural products 56 (7), 1123-1129, 1993 | 130 | 1993 |
Novel marine and microbial natural product inhibitors of vacuolar ATPase JA Beutler, TC McKee Current medicinal chemistry 10 (9), 787-796, 2003 | 109 | 2003 |
Inhibition of transcription factor NF-κB signaling proteins IKKβ and p65 through specific cysteine residues by epoxyquinone A monomer: correlation with its anti-cancer cell … MC Liang, S Bardhan, EA Pace, D Rosman, JA Beutler, JA Porco Jr, ... Biochemical pharmacology 71 (5), 634-645, 2006 | 104 | 2006 |
Review of natural products A DerMarderosian, JA Beutler Facts and Comparisons, 2010 | 103 | 2010 |