Histone deacetylase 6 structure and molecular basis of catalysis and inhibition Y Hai, D Christianson Nature Chemical Biology 12 (September), 741-747, 2016 | 427 | 2016 |
ARID1A-mutated ovarian cancers depend on HDAC6 activity W Bitler, B.G., Wu, S., Park, P.H., Hai, Y., Aird, K.M., Wang, Y., Zhai, Y ... Nature Cell Biology, 2017 | 213 | 2017 |
Histone deacetylase 10 structure and molecular function as a polyamine deacetylase Y Hai, SA Shinsky, NJ Porter, DW Christianson Nature Communications 8, 15368, 2017 | 175 | 2017 |
SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis. TY Ohashi M, Liu F, Hai Y, Chen M, Tang MC, Yang Z, Sato M, Watanabe K, Houk KN Nature 549 (7673), 502-506, 2017 | 165 | 2017 |
Luminescent zinc salen complexes as single and two-photon fluorescence subcellular imaging probes Y Hai, J-J Chen, P Zhao, H Lv, Y Yu, P Xu, and J-L Zhang Chemical Communications 47, 2435-2437, 2011 | 122 | 2011 |
Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections EL D'Antonio, B Ullman, SC Roberts, UG Dixit, ME Wilson, ... Arch. Biochem. Biophys 535 (2), 163-176, 2013 | 86 | 2013 |
Rational design of ZnSalen as a single and two photon activatable fluorophore in living cells J Jing, JJ Chen, Y Hai, J Zhan, P Xu, JL Zhang Chemical Science 3, 3313-3320, 2012 | 62 | 2012 |
Genome mining of alkaloidal terpenoids from a hybrid terpene and nonribosomal peptide biosynthetic pathway DA Yee, TB Kakule, W Cheng, M Chen, CTY Chong, Y Hai, LF Hang, ... Journal of the American Chemical Society 142 (2), 710-714, 2019 | 47 | 2019 |
Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI Y Cai, Y Hai, M Ohashi, CS Jamieson, M Garcia-Borras, KN Houk, J Zhou, ... Nature chemistry 11 (9), 812-820, 2019 | 42 | 2019 |
Biosynthesis of Mycotoxin Fusaric Acid and Application of a PLP-Dependent Enzyme for Chemoenzymatic Synthesis of Substituted l-Pipecolic Acids Y Hai, M Chen, A Huang, Y Tang J. Am. Chem. Soc., 2020 | 38 | 2020 |
Structural Basis for Aza-Glycine Stabilization of Collagen AJ Kasznel, Y Zhang, Y Hai, D Chenoweth Journal of the American Chemical Society, 2017 | 37 | 2017 |
Structure-guided function discovery of an NRPS-like glycine betaine reductase for choline biosynthesis in fungi Y Hai, AM Huang, Y Tang Proceedings of the National Academy of Science, 2019 | 33 | 2019 |
A sensitive and quantitative autolysosome probe for detecting autophagic activity in live and prestained fixed cells JJ Chen, J Jing, H Chang, Y Rong, Y Hai, J Tang, JL Zhang, P Xu Autophagy 9, 894-904, 2013 | 32 | 2013 |
Molecular assembly directed by metal–aromatic interactions: control of the aggregation and photophysical properties of Zn–Salen complexes by aromatic mercuration YB Cai, J Zhan, Y Hai, JL Zhang Chem. Eur. J. 18, 4242-4249, 2012 | 28 | 2012 |
Biosynthesis of Long-Chain N-Acyl Amide by a Truncated Polyketide Synthase–Nonribosomal Peptide Synthetase Hybrid Megasynthase in Fungi Y Hai, Y Tang Journal of the American Chemical Society, 2018 | 26 | 2018 |
Crystal structure of an arginase-like protein from Trypanosoma brucei that evolved without a binuclear manganese cluster Y Hai, EJ Kerkhoven, MP Barrett, DW Christianson Biochemistry 54 (2), 458-471, 2015 | 25 | 2015 |
Structure and function of non-native metal clusters in human arginase I. ED D'Antonio, Y Hai, DW Christianson Biochemistry 51 (42), 8399-8409, 2012 | 25 | 2012 |
Enzyme-Catalyzed Intramolecular Enantioselective Hydroalkoxylation SS Gao, M Garcia-Borràs, JS Barber, Y Hai, A Duan, NK Garg, KN Houk, ... Journal of the American Chemical Society, 2017 | 23 | 2017 |
Fungal siderophore biosynthesis catalysed by an iterative nonribosomal peptide synthetase YT Y Hai, M Jenner Chemical Science, 2020 | 22 | 2020 |
Biosynthesis of Amino Acid Derived α-Pyrones by an NRPS–NRPKS Hybrid Megasynthetase in Fungi Y Hai, A Huang, Y Tang Journal of Natural Products, 2020 | 22 | 2020 |