Martin R Sprick

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Andreas TrumppHI-STEM & DKFZ, Heidelberg, GermanyPotvrđena adresa e-pošte na hi-stem.de
jan paul medemaHoogleraar Exp Oncology and RadiobiologyPotvrđena adresa e-pošte na amc.nl
Wilko WeichertInstitute of Pathology, Technical University Munich (TUM)Potvrđena adresa e-pošte na tum.de
Giorgio StassiFull Professor in Medical Laboratory Science and Technology. University of PalermoPotvrđena adresa e-pošte na unipa.it
Louis Vermeulen MD PhDProfessor Molecular Oncology - Amsterdam University Medical Centers, University of AmsterdamPotvrđena adresa e-pošte na amsterdamumc.nl
Irene BaccelliPotvrđena adresa e-pošte na umontreal.ca
Albrecht Stenzinger, MDInstitute of Pathology, University Hospital Heidelberg, GermanyPotvrđena adresa e-pošte na med.uni-heidelberg.de
Matilde TodaroUniversity Researcher, University of PalermoPotvrđena adresa e-pošte na unipa.it
Anne Grosse-WildeSeattle GeneticsPotvrđena adresa e-pošte na seagen.com
Felipe de Sousa e MeloGenentechPotvrđena adresa e-pošte na gene.com
Massimo SainiUniversity of BaselPotvrđena adresa e-pošte na unibas.ch
Roland EilsProfessor for Digital Health, Charité-Universitätsmedizin Berlin and Berlin Institute of HealthPotvrđena adresa e-pošte na charite.de
JB TuynmanColorectal surgeon, MD, PhD, colorectal surgery, amsterdam UMC, surgical trainingPotvrđena adresa e-pošte na amsterdamumc.nl
Matthias SchlesnerBiomedical Informatics, Data Mining and Data Analytics, Augsburg UniversityPotvrđena adresa e-pošte na informatik.uni-augsburg.de
John BlenisProfessor of Pharmacology, Weill Cornell MedicinePotvrđena adresa e-pošte na med.cornell.edu
Peter JuoAssociate Professor, Tufts UniversityPotvrđena adresa e-pošte na tufts.edu
Sascha PahernikProfessor für UrologiePotvrđena adresa e-pošte na klinikum-nuernberg.de
Matthias GoebelerUniversity of Würzburg, University of Heidelberg, University of Giessen, University of MünsterPotvrđena adresa e-pošte na klinik.uni-wuerzburg.de
Joost Verhoeff MD PhDassociate professor of radiation oncology, UMC UtrechtPotvrđena adresa e-pošte na drverhoeff.nl
Strobel ODept of General Surgery, Medical University of ViennaPotvrđena adresa e-pošte na meduniwien.ac.at

Prati

Martin R Sprick

HI-STEM gGmbH, DKFZ-Heidelberg

Potvrđena adresa e-pošte na dkfz.de - Početna stranica

Cancer Stem Cells Pancreatic Cancer Renal Cancer Ovarian Cancer Caspases


Naslov Poredaj po navodima Poredaj po godini Poredaj po naslovu	Citirano Citirano	Godina
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment L Vermeulen, F De Sousa E Melo, M Van Der Heijden, K Cameron, ... Nature cell biology 12 (5), 468-476, 2010	1936	2010
Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay I Baccelli, A Schneeweiss, S Riethdorf, A Stenzinger, A Schillert, V Vogel, ... Nature biotechnology 31 (6), 539-544, 2013	1062	2013
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2 MR Sprick, MA Weigand, E Rieser, CT Rauch, P Juo, J Blenis, ... Immunity 12 (6), 599-609, 2000	997	2000
Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity L Vermeulen, M Todaro, F de Sousa Mello, MR Sprick, K Kemper, ... Proceedings of the National Academy of Sciences 105 (36), 13427-13432, 2008	857	2008
Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8 MR Sprick, E Rieser, H Stahl, A Grosse-Wilde, MA Weigand, H Walczak The EMBO journal 21 (17), 4520-4530, 2002	504	2002
Cancer stem cells–old concepts, new insights L Vermeulen, MR Sprick, K Kemper, G Stassi, JP Medema Cell death & differentiation 15 (6), 947-958, 2008	430	2008
The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation K Kemper, MR Sprick, M de Bree, A Scopelliti, L Vermeulen, M Hoek, ... Cancer research 70 (2), 719-729, 2010	423	2010
The interplay between the Bcl-2 family and death receptor-mediated apoptosis MR Sprick, H Walczak Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1644 (2-3), 125-132, 2004	333	2004
Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by … TM Ganten, TL Haas, J Sykora, H Stahl, MR Sprick, SC Fas, A Krueger, ... Cell Death & Differentiation 11 (1), S86-S96, 2004	255	2004
CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma EM Noll, C Eisen, A Stenzinger, E Espinet, A Muckenhuber, C Klein, ... Nature medicine 22 (3), 278-287, 2016	185	2016
Screening drug effects in patient‐derived cancer cells links organoid responses to genome alterations J Jabs, FM Zickgraf, J Park, S Wagner, X Jiang, K Jechow, K Kleinheinz, ... Molecular systems biology 13 (11), 955, 2017	169	2017
Oncogenic K-Ras turns death receptors into metastasis-promoting receptors in human and mouse colorectal cancer cells FJH Hoogwater, MW Nijkamp, N Smakman, EJA Steller, BL Emmink, ... Gastroenterology 138 (7), 2357-2367, 2010	154	2010
Proteasome Inhibition Results in TRAIL Sensitization of Primary Keratinocytes by Removing the Resistance-Mediating Block of Effector Caspase Maturation M Leverkus, MR Sprick, T Wachter, T Mengling, B Baumann, E Serfling, ... Molecular and Cellular Biology 23 (3), 777-790, 2003	149	2003
TNF-related apoptosis-inducing ligand mediates tumoricidal activity of human monocytes stimulated by Newcastle disease virus B Washburn, MA Weigand, A Grosse-Wilde, M Janke, H Stahl, E Rieser, ... The Journal of Immunology 170 (4), 1814-1821, 2003	147	2003
Suppression of cFLIP is sufficient to sensitize human melanoma cells to TRAIL-and CD95L-mediated apoptosis P Geserick, C Drewniok, M Hupe, TL Haas, P Diessenbacher, MR Sprick, ... Oncogene 27 (22), 3211-3220, 2008	143	2008
TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer‐specific apoptosis within a therapeutic window R Koschny, TM Ganten, J Sykora, TL Haas, MR Sprick, A Kolb, ... Hepatology 45 (3), 649-658, 2007	140	2007
Survival of pancreatic cancer cells lacking KRAS function MD Muzumdar, PY Chen, KJ Dorans, KM Chung, A Bhutkar, E Hong, ... Nature communications 8 (1), 1090, 2017	138	2017
Bortezomib Sensitizes Primary Human Astrocytoma Cells of WHO Grades I to IV for Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Induced Apoptosis R Koschny, H Holland, J Sykora, TL Haas, MR Sprick, TM Ganten, ... Clinical Cancer Research 13 (11), 3403-3412, 2007	133	2007
Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors M Djurec, O Graña, A Lee, K Troulé, E Espinet, L Cabras, C Navas, ... Proceedings of the National Academy of Sciences 115 (6), E1147-E1156, 2018	121	2018
A synergistic interaction between Chk1-and MK2 inhibitors in KRAS-mutant cancer F Dietlein, B Kalb, M Jokic, EM Noll, A Strong, L Tharun, L Ozretić, ... Cell 162 (1), 146-159, 2015	120	2015

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