| ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules A Leaver-Fay, M Tyka, SM Lewis, OF Lange, J Thompson, R Jacak, ... Methods in enzymology 487, 545-574, 2011 | 1628 | 2011 |
| Sub-angstrom accuracy in protein loop reconstruction by robotics-inspired conformational sampling DJ Mandell, EA Coutsias, T Kortemme Nature methods 6 (8), 551-552, 2009 | 448 | 2009 |
| Biocontainment of genetically modified organisms by synthetic protein design DJ Mandell, MJ Lajoie, MT Mee, R Takeuchi, G Kuznetsov, JE Norville, ... Nature 518 (7537), 55-60, 2015 | 374 | 2015 |
| A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin-dependent kinase II holoenzyme LH Chao, MM Stratton, IH Lee, OS Rosenberg, J Levitz, DJ Mandell, ... Cell 146 (5), 732-745, 2011 | 231 | 2011 |
| Computer-aided design of functional protein interactions DJ Mandell, T Kortemme Nature chemical biology 5 (11), 797-807, 2009 | 191 | 2009 |
| A general strategy to construct small molecule biosensors in eukaryotes J Feng, BW Jester, CE Tinberg, DJ Mandell, MS Antunes, R Chari, ... Elife 4, e10606, 2015 | 133 | 2015 |
| Strengths of hydrogen bonds involving phosphorylated amino acid side chains DJ Mandell, I Chorny, ES Groban, SE Wong, E Levine, CS Rapp, ... Journal of the American Chemical Society 129 (4), 820-827, 2007 | 117 | 2007 |
| Backbone flexibility in computational protein design DJ Mandell, T Kortemme Current opinion in biotechnology 20 (4), 420-428, 2009 | 110 | 2009 |
| Genome-wide analysis of p53 under hypoxic conditions EM Hammond, DJ Mandell, A Salim, AJ Krieg, TM Johnson, HA Shirazi, ... Molecular and cellular biology 26 (9), 3492-3504, 2006 | 110 | 2006 |
| Computational design of a modular protein sense-response system AA Glasgow, YM Huang, DJ Mandell, M Thompson, R Ritterson, ... Science 366 (6468), 1024-1028, 2019 | 50 | 2019 |
| Assessment of flexible backbone protein design methods for sequence library prediction in the therapeutic antibody herceptin–HER2 interface M Babor, DJ Mandell, T Kortemme Protein Science 20 (6), 1082-1089, 2011 | 35 | 2011 |
| EGFR-binding peptides: From computational design towards tumor-targeting of adeno-associated virus capsids RC Feiner, I Kemker, L Krutzke, E Allmendinger, DJ Mandell, N Sewald, ... International journal of molecular sciences 21 (24), 9535, 2020 | 8 | 2020 |
| Synthetic auxotrophy remains stable after continuous evolution and in coculture with mammalian cells AM Kunjapur, MG Napolitano, E Hysolli, K Noguera, EM Appleton, ... Science Advances 7 (27), eabf5851, 2021 | 6 | 2021 |
| Production of seleno-biologics in genomically recoded organisms DJ Mandell, CJ Gregg, R Thyer, AD Ellington, PB Stranges US Patent App. 16/329,761, 2019 | 4 | 2019 |
| Biosensors engineered from conditionally stable ligand-binding domains GM Church, J Feng, DJ Mandell, D Baker, S Fields, BW Jester, ... US Patent 9,766,255, 2017 | 2 | 2017 |
| Human dnase for lung disease DJ Mandell US Patent App. 17/323,383, 2021 | | 2021 |
| Non-standard amino acid containing compositions and uses thereof DJ Mandell, CJ Gregg, PB Stranges US Patent App. 17/144,946, 2021 | | 2021 |
| Methods of making polypeptides with non-standard amino acids using genomically recoded organisms GM Church, CJ Gregg, MJ Lajoie, DJ Mandell US Patent 10,910,085, 2021 | | 2021 |
| Protein Stability-based Small Molecule Biosensors and Methods GM Church, DJ Mandell, J Feng US Patent App. 16/083,935, 2020 | | 2020 |
| Continuous Evolution of Engineered Synthetic Auxotrophs for Industrial Application A Kunjapur, MG Napolitano, M Schubert, E Appleton, K Noguera, ... 2018 AIChE Annual Meeting, 2018 | | 2018 |
