Yu Wai Chen
Prediction of the SARS-CoV-2 (2019-nCoV) 3C-like protease (3CLpro) structure: virtual screening reveals velpatasvir, ledipasvir, and other drug repurposing candidates [version …
YW Chen, CPB Yiu, KY Wong
F1000Research 9, 129, 2020
Structure of UreG/UreF/UreH complex reveals how urease accessory proteins facilitate maturation of Helicobacter pylori urease
YH Fong, HC Wong, MH Yuen, PH Lau, YW Chen, KB Wong
PLoS biology 11 (10), e1001678, 2013
Rational design of a novel fluorescent biosensor for β-lactam antibiotics from a class A β-lactamase
PH Chan, HB Liu, YW Chen, KC Chan, CW Tsang, YC Leung, KY Wong
Journal of the American Chemical Society 126 (13), 4074-4075, 2004
Contribution of Buried Hydrogen Bonds to Protein Stability The Crystal Structures of Two Barnase Mutants
YW Chen, AR Fersht, K Henrick
Journal of molecular biology 234 (4), 1158-1170, 1993
Simeprevir potently suppresses SARS-CoV-2 replication and synergizes with remdesivir
HS Lo, KPY Hui, HM Lai, X He, KS Khan, S Kaur, J Huang, Z Li, ...
ACS central science 7 (5), 792-802, 2021
Crystal structure of a dimeric chymotrypsin inhibitor 2 mutant containing an inserted glutamine repeat
YW Chen, K Stott, MF Perutz
Proceedings of the National Academy of Sciences 96 (4), 1257-1261, 1999
The structure of the AXH domain of spinocerebellar ataxin-1
YW Chen, MD Allen, DB Veprintsev, J Löwe, M Bycroft
Journal of Biological Chemistry 279 (5), 3758-3765, 2004
Assembly of Preactivation Complex for Urease Maturation in Helicobacter pylori CRYSTAL STRUCTURE OF UreF-UreH PROTEIN COMPLEX
YH Fong, HC Wong, CP Chuck, YW Chen, H Sun, KB Wong
Journal of Biological Chemistry 286 (50), 43241-43249, 2011
Does NMR mean “not for molecular replacement”? Using NMR-based search models to solve protein crystal structures
YW Chen, EJ Dodson, GJ Kleywegt
Structure 8 (11), R213-R220, 2000
Structure of the C-terminal sterile α-motif (SAM) domain of human p73α
WK Wang, M Bycroft, NW Foster, AM Buckle, AR Fersht, YW Chen
Acta Crystallographica Section D: Biological Crystallography 57 (4), 545-551, 2001
First glimpse of the peptide presentation by rhesus macaque MHC class I: crystal structures of Mamu-A* 01 complexed with two immunogenic SIV epitopes and insights into CTL escape
F Chu, Z Lou, YW Chen, Y Liu, B Gao, L Zong, AH Khan, JI Bell, Z Rao, ...
The Journal of Immunology 178 (2), 944-952, 2007
Phosphorylation of FE65 Ser610 by serum- and glucocorticoid-induced kinase 1 modulates Alzheimer's disease amyloid precursor protein processing
WNV Chow, JCK Ngo, W Li, YW Chen, KMV Tam, HYE Chan, CCJ Miller, ...
Biochemical Journal 470 (3), 303-317, 2015
Crystal structures of influenza nucleoprotein complexed with nucleic acid provide insights into the mechanism of RNA interaction
YS Tang, S Xu, YW Chen, JH Wang, PC Shaw
Nucleic Acids Research 49 (7), 4144-4154, 2021
Self-Assembly and Conformational Heterogeneity of the AXH Domain of Ataxin-1: An Unusual Example of a Chameleon Fold
C de Chiara, M Rees, RP Menon, K Pauwels, C Lawrence, PV Konarev, ...
Biophysical journal 104 (6), 1304-1313, 2013
Solution solution: using NMR models for molecular replacement
YW Chen
Acta Crystallographica Section D: Biological Crystallography 57 (10), 1457-1461, 2001
Crystal structure of ribosomal protein L30e from the extreme thermophile Thermococcus celer: thermal stability and RNA binding
YW Chen, M Bycroft, KB Wong
Biochemistry 42 (10), 2857-2865, 2003
Conformational dynamics of the helix 10 region as an allosteric site in class A β-lactamase inhibitory binding
L Huang, PK So, YW Chen, YC Leung, ZP Yao
Journal of the American Chemical Society 142 (32), 13756-13767, 2020
Solution Model of the Intrinsically Disordered Polyglutamine Tract-Binding Protein-1
M Rees, C Gorba, C de Chiara, TTT Bui, M Garcia-Maya, AF Drake, ...
Biophysical journal 102 (7), 1608-1616, 2012
Solution structure and thermal stability of ribosomal protein L30e from hyperthermophilic archaeon Thermococcus celer
KB Wong, CF Lee, SH Chan, TY Leung, YW Chen, M Bycroft
Protein science 12 (7), 1483-1495, 2003
A systematic case study on using NMR models for molecular replacement: p53 tetramerization domain revisited
YW Chen, GM Clore
Acta Crystallographica Section D: Biological Crystallography 56 (12), 1535-1540, 2000
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