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Thomas Weber
Thomas Weber
Spark Therapeutics
Verified email at sparktx.com
Title
Cited by
Cited by
Year
SNAREpins: minimal machinery for membrane fusion
T Weber, BV Zemelman, JA McNew, B Westermann, M Gmachl, F Parlati, ...
Cell 92 (6), 759-772, 1998
29601998
Cathepsin D targeted by acid sphingomyelinase‐derived ceramide
M Heinrich, M Wickel, W Schneider‐Brachert, C Sandberg, J Gahr, ...
The EMBO journal, 1999
4461999
Reconstitution of Ca2+-regulated membrane fusion by synaptotagmin and SNAREs
WC Tucker, T Weber, ER Chapman
Science 304 (5669), 435-438, 2004
4382004
Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors
JA McNew, T Weber, F Parlati, RJ Johnston, TJ Melia, TH Söllner, ...
The Journal of cell biology 150 (1), 105-118, 2000
3792000
Pre-existing anti–adeno-associated virus antibodies as a challenge in AAV gene therapy
V Louis Jeune, JA Joergensen, RJ Hajjar, T Weber
Human gene therapy methods 24 (2), 59-67, 2013
3282013
Intracellular transport of recombinant adeno-associated virus vectors
M Nonnenmacher, T Weber
Gene therapy 19 (6), 649-658, 2012
3082012
Rapid and efficient fusion of phospholipid vesicles by the α-helical core of a SNARE complex in the absence of an N-terminal regulatory domain
F Parlati, T Weber, JA McNew, B Westermann, TH Söllner, JE Rothman
Proceedings of the National Academy of Sciences 96 (22), 12565-12570, 1999
3021999
Functional architecture of an intracellular membrane t-SNARE
R Fukuda, JA McNew, T Weber, F Parlati, T Engel, W Nickel, JE Rothman, ...
Nature 407 (6801), 198-202, 2000
2912000
Regulation of membrane fusion by the membrane-proximal coil of the t-SNARE during zippering of SNAREpins
TJ Melia, T Weber, JA McNew, LE Fisher, RJ Johnston, F Parlati, ...
The Journal of cell biology 158 (5), 929-940, 2002
2462002
Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs
W Nickel, T Weber, JA McNew, F Parlati, TH Söllner, JE Rothman
Proceedings of the National Academy of Sciences 96 (22), 12571-12576, 1999
2381999
Adeno-associated virus 2 infection requires endocytosis through the CLIC/GEEC pathway
M Nonnenmacher, T Weber
Cell host & microbe 10 (6), 563-576, 2011
2372011
The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion
JA McNew, T Weber, DM Engelman, TH Söllner, JE Rothman
Molecular cell 4 (3), 415-421, 1999
2001999
Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models
K Rapti, V Louis-Jeune, E Kohlbrenner, K Ishikawa, D Ladage, ...
Molecular Therapy 20 (1), 73-83, 2012
1922012
Expressing transgenes that exceed the packaging capacity of adeno-associated virus capsids
K Chamberlain, JM Riyad, T Weber
Human gene therapy methods 27 (1), 1-12, 2016
1782016
Gene therapy for heart failure
L Tilemann, K Ishikawa, T Weber, RJ Hajjar
Circulation research 110 (5), 777-793, 2012
1572012
Ceramide as an activator lipid of cathepsin D
M Heinrich, M Wickel, S Winoto-Morbach, W Schneider-Brachert, T Weber, ...
Cellular Peptidases in Immune Functions and Diseases 2, 305-315, 2002
1552002
SNAREpins are functionally resistant to disruption by NSF and αSNAP
T Weber, F Parlati, JA McNew, RJ Johnston, B Westermann, TH Söllner, ...
The Journal of cell biology 149 (5), 1063-1072, 2000
1522000
Evidence for H (+)-induced insertion of influenza hemagglutinin HA2 N-terminal segment into viral membrane
T Weber, G Paesold, C Galli, R Mischler, G Semenza, J Brunner
Journal of Biological Chemistry 269 (28), 18353-18358, 1994
1391994
2-(Tributylstannyl)-4-[3-(trifluoromethyl)-3H-diazirin-3-yl] benzyl alcohol: a building block for photolabeling and crosslinking reagents of very high specific radioactivity
T Weber, J Brunner
Journal of the American Chemical Society 117 (11), 3084-3095, 1995
1111995
Altering AAV tropism with mosaic viral capsids
L Gigout, P Rebollo, N Clement, KH Warrington, N Muzyczka, RM Linden, ...
Molecular Therapy 11 (6), 856-865, 2005
1022005
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