Systems biotechnology for strain improvement SY Lee, DY Lee, TY Kim Trends in biotechnology 23 (7), 349-358, 2005 | 432 | 2005 |
MEMOTE for standardized genome-scale metabolic model testing C Lieven, ME Beber, BG Olivier, FT Bergmann, M Ataman, P Babaei, ... Nature biotechnology 38 (3), 272-276, 2020 | 403 | 2020 |
Metabolic engineering of Escherichia coli for enhanced production of succinic acid, based on genome comparison and in silico gene knockout simulation SJ Lee, DY Lee, TY Kim, BH Kim, J Lee, SY Lee Appl. Environ. Microbiol. 71 (12), 7880-7887, 2005 | 380 | 2005 |
Recon 2.2: from reconstruction to model of human metabolism N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ... Metabolomics 12 (7), 109, 2016 | 330 | 2016 |
Synthetic fusion protein design and applications K Yu, C Liu, BG Kim, DY Lee Biotechnology advances 33 (1), 155-164, 2015 | 258 | 2015 |
A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ... Cell Systems 3 (5), 434-443. e8, 2016 | 253 | 2016 |
Combined in silico modeling and metabolomics analysis to characterize fed‐batch CHO cell culture S Selvarasu, YS Ho, WPK Chong, NSC Wong, FNK Yusufi, YY Lee, ... Biotechnology and bioengineering 109 (6), 1415-1429, 2012 | 246 | 2012 |
N-Glycosylation design and control of therapeutic monoclonal antibodies S Sha, C Agarabi, K Brorson, DY Lee, S Yoon Trends in biotechnology 34 (10), 835-846, 2016 | 171 | 2016 |
Metabolite essentiality elucidates robustness of Escherichia coli metabolism PJ Kim, DY Lee, TY Kim, KH Lee, H Jeong, SY Lee, S Park Proceedings of the National Academy of Sciences 104 (34), 13638-13642, 2007 | 171 | 2007 |
MetaFluxNet: the management of metabolic reaction information and quantitative metabolic flux analysis DY Lee, H Yun, S Park, SY Lee Bioinformatics 19 (16), 2144-2146, 2003 | 171 | 2003 |
Genome and evolution of the shade‐requiring medicinal herb Panax ginseng NH Kim, M Jayakodi, SC Lee, BS Choi, W Jang, J Lee, HH Kim, ... Plant biotechnology journal 16 (11), 1904-1917, 2018 | 162 | 2018 |
Codon Optimization OnLine (COOL): a web-based multi-objective optimization platform for synthetic gene design JX Chin, BKS Chung, DY Lee Bioinformatics 30 (15), 2210-2212, 2014 | 161 | 2014 |
Genome-scale metabolic reconstruction and in silico analysis of methylotrophic yeast Pichia pastoris for strain improvement BKS Chung, S Selvarasu, A Camattari, J Ryu, H Lee, J Ahn, H Lee, ... Microbial cell factories 9 (1), 50, 2010 | 157 | 2010 |
Metabolomics-driven approach for the improvement of Chinese hamster ovary cell growth: overexpression of malate dehydrogenase II WPK Chong, SG Reddy, FNK Yusufi, DY Lee, NSC Wong, CK Heng, ... Journal of biotechnology 147 (2), 116-121, 2010 | 125 | 2010 |
Software applications for flux balance analysis M Lakshmanan, G Koh, BKS Chung, DY Lee Briefings in bioinformatics 15 (1), 108-122, 2014 | 118 | 2014 |
LC‐MS‐based metabolic characterization of high monoclonal antibody‐producing Chinese hamster ovary cells WPK Chong, SH Thng, AP Hiu, DY Lee, ECY Chan, YS Ho Biotechnology and bioengineering 109 (12), 3103-3111, 2012 | 109 | 2012 |
Computational codon optimization of synthetic gene for protein expression BKS Chung, DY Lee BMC systems biology 6 (1), 134, 2012 | 107 | 2012 |
Mammalian Systems Biotechnology Reveals Global Cellular Adaptations in a Recombinant CHO Cell Line FNK Yusufi, M Lakshmanan, YS Ho, BLW Loo, P Ariyaratne, Y Yang, ... Cell Systems 4 (5), 530-542. e6, 2017 | 105 | 2017 |
Genome‐scale modeling and in silico analysis of ethanologenic bacteria Zymomonas mobilis H Widiastuti, JY Kim, S Selvarasu, IA Karimi, H Kim, JS Seo, DY Lee Biotechnology and bioengineering 108 (3), 655-665, 2011 | 103 | 2011 |
Ginseng Genome Database: an open-access platform for genomics of Panax ginseng M Jayakodi, BS Choi, SC Lee, NH Kim, JY Park, W Jang, M Lakshmanan, ... BMC plant biology 18 (1), 62, 2018 | 95 | 2018 |