WNT and β-catenin signalling: diseases and therapies RT Moon, AD Kohn, GVD Ferrari, A Kaykas Nature reviews genetics 5 (9), 691-701, 2004 | 2301 | 2004 |
Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements MT Veeman, DC Slusarski, A Kaykas, SH Louie, RT Moon Current biology 13 (8), 680-685, 2003 | 1094 | 2003 |
p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells RJ Ihry, KA Worringer, MR Salick, E Frias, D Ho, K Theriault, S Kommineni, ... Nature medicine 24 (7), 939-946, 2018 | 1052 | 2018 |
Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning CM Sellgren, J Gracias, B Watmuff, JD Biag, JM Thanos, PB Whittredge, ... Nature neuroscience 22 (3), 374-385, 2019 | 727 | 2019 |
Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy J Robitaille, MLE MacDonald, A Kaykas, LC Sheldahl, J Zeisler, MP Dubé, ... Nature genetics 32 (2), 326-330, 2002 | 556 | 2002 |
A viral strategy for targeting and manipulating interneurons across vertebrate species J Dimidschstein, Q Chen, R Tremblay, SL Rogers, GA Saldi, L Guo, Q Xu, ... Nature neuroscience 19 (12), 1743-1749, 2016 | 540 | 2016 |
Functional genomic analysis of the Wnt-wingless signaling pathway R DasGupta, A Kaykas, RT Moon, N Perrimon Science 308 (5723), 826-833, 2005 | 422 | 2005 |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain CL Thompson, L Ng, V Menon, S Martinez, CK Lee, K Glattfelder, ... Neuron 83 (2), 309-323, 2014 | 310 | 2014 |
Genetic ablation of AXL does not protect human neural progenitor cells and cerebral organoids from Zika virus infection MF Wells, MR Salick, O Wiskow, DJ Ho, KA Worringer, RJ Ihry, ... Cell stem cell 19 (6), 703-708, 2016 | 303 | 2016 |
CORTECON: a temporal transcriptome analysis of in vitro human cerebral cortex development from human embryonic stem cells J Van De Leemput, NC Boles, TR Kiehl, B Corneo, P Lederman, V Menon, ... Neuron 83 (1), 51-68, 2014 | 223 | 2014 |
Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization A Kaykas, J Yang-Snyder, M Héroux, KV Shah, M Bouvier, RT Moon Nature cell biology 6 (1), 52-58, 2004 | 200 | 2004 |
DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery C Ye, DJ Ho, M Neri, C Yang, T Kulkarni, R Randhawa, M Henault, ... Nature communications 9 (1), 4307, 2018 | 195 | 2018 |
A single-cell roadmap of lineage bifurcation in human ESC models of embryonic brain development Z Yao, JK Mich, S Ku, V Menon, AR Krostag, RA Martinez, L Furchtgott, ... Cell stem cell 20 (1), 120-134, 2017 | 158 | 2017 |
ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157 D Feuerbach, P Schindler, C Barske, S Joller, E Beng-Louka, ... Neuroscience letters 660, 109-114, 2017 | 135 | 2017 |
CD40 and LMP-1 both signal from lipid rafts but LMP-1 assembles a distinct, more efficient signaling complex A Kaykas, K Worringer, B Sugden The EMBO journal 20 (11), 2641-2654, 2001 | 132 | 2001 |
A plasmid-based system for expressing small interfering RNA libraries in mammalian cells A Kaykas, RT Moon BMC Cell Biology 5, 1-11, 2004 | 115 | 2004 |
The amino-terminus and membrane-spanning domains of LMP-1 inhibit cell proliferation A Kaykas, B Sugden Oncogene 19 (11), 1400-1410, 2000 | 98 | 2000 |
Creating patient-specific neural cells for the in vitro study of brain disorders KJ Brennand, MC Marchetto, N Benvenisty, O Brüstle, A Ebert, ... Stem cell reports 5 (6), 933-945, 2015 | 88 | 2015 |
Genome-scale CRISPR screens identify human pluripotency-specific genes RJ Ihry, MR Salick, DJ Ho, M Sondey, S Kommineni, S Paula, J Raymond, ... Cell reports 27 (2), 616-630. e6, 2019 | 82 | 2019 |
P53 toxicity is a hurdle to CRISPR/CAS9 screening and engineering in human pluripotent stem cells RJ Ihry, KA Worringer, MR Salick, E Frias, D Ho, K Theriault, S Kommineni, ... bioRxiv, 168443, 2017 | 58 | 2017 |