Prati
Brent Dorr
Brent Dorr
Investigator at GlaxoSmithKline R&D, Synthetic Biochemistry
Potvrđena adresa e-pošte na gsk.com
Naslov
Citirano
Citirano
Godina
A general strategy for the evolution of bond-forming enzymes using yeast display
I Chen, BM Dorr, DR Liu
Proceedings of the National Academy of Sciences 108 (28), 11399-11404, 2011
5992011
Solvent accessible surface area approximations for rapid and accurate protein structure prediction
E Durham, B Dorr, N Woetzel, R Staritzbichler, J Meiler
Journal of molecular modeling 15, 1093-1108, 2009
2942009
Reprogramming the specificity of sortase enzymes
BM Dorr, HO Ham, C An, EL Chaikof, DR Liu
Proceedings of the National Academy of Sciences 111 (37), 13343-13348, 2014
2002014
Cellular uptake mechanisms and endosomal trafficking of supercharged proteins
DB Thompson, R Villaseñor, BM Dorr, M Zerial, DR Liu
Chemistry & biology 19 (7), 831-843, 2012
1552012
Evolution of bond-forming enzymes
DR Liu, I Chen, BM Dorr
US Patent 9,267,127, 2016
562016
Enzymatic amidation for industrial applications
BM Dorr, DE Fuerst
Current Opinion in Chemical Biology 43, 127-133, 2018
502018
Exploring symmetry as an avenue to the computational design of large protein domains
C Fortenberry, EA Bowman, W Proffitt, B Dorr, S Combs, J Harp, L Mizoue, ...
Journal of the American Chemical Society 133 (45), 18026-18029, 2011
422011
Laboratory evolution of a sortase enzyme that modifies amyloid-β protein
CJ Podracky, C An, A DeSousa, BM Dorr, DM Walsh, DR Liu
Nature chemical biology 17 (3), 317-325, 2021
412021
In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A
HO Ham, Z Qu, CA Haller, BM Dorr, E Dai, W Kim, DR Liu, EL Chaikof
Nature Communications 7 (1), 11140, 2016
352016
Octarellin VI: Using Rosetta to Design a Putative Artificial (β/α)8 Protein
M Figueroa, N Oliveira, A Lejeune, KW Kaufmann, BM Dorr, A Matagne, ...
PLoS One 8 (8), e71858, 2013
322013
Immobilization of actively thromboresistant assemblies on sterile blood contacting surfaces
Z Qu, V Krishnamurthy, CA Haller, MBM Dorr, MUM Marzec, MS Hurst, ...
Advanced healthcare materials 3 (1), 30, 2014
292014
Design of native-like proteins through an exposure-dependent environment potential
S DeLuca, B Dorr, J Meiler
Biochemistry 50 (40), 8521-8528, 2011
182011
Evolved sortases and uses thereof
DR Liu, BM Dorr
US Patent 10,202,593, 2019
142019
PROLink Single Step Circularization and Purification Procedure for the Generation of an Improved Variant of Human Growth Hormone
N Rasche, J Tonillo, M Rieker, S Becker, B Dorr, D Ter-Ovanesyan, ...
Bioconjugate Chemistry 27 (5), 1341-1347, 2016
132016
Carboxyesterase polypeptides for amide coupling
R Voladri, D Entwistle, CM Micklitsch, V Mitchell, N Dellas, X Zhang, ...
US Patent 11,015,180, 2021
32021
Evolution of bond-forming enzymes
DR Liu, I Chen, BM Dorr
US Patent App. 15/049,465, 2016
22016
Sortase-catalyzed immobilization, release, and replacement of functional molecules on solid surfaces
E Chaikof, Z Qu, C Haller, DR Liu, BM Dorr
US Patent App. 14/439,787, 2015
22015
Carboxyesterase biocatalysts
KK Brown, BM Dorr, DE Fuerst, KJ Honicker, LS Jordan, JP Morrison, ...
US Patent 11,535,833, 2022
12022
Carboxyesterase biocatalysts
KK Brown, BM Dorr, DE Fuerst, KJ Honicker, LS Jordan, JP Morrison, ...
US Patent App. 18/046,295, 2023
2023
Method for screening libraries
B Dorr, G Scavello
US Patent App. 17/640,630, 2022
2022
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