| Identification of a unique TGF-β–dependent molecular and functional signature in microglia O Butovsky, MP Jedrychowski, CS Moore, R Cialic, AJ Lanser, G Gabriely, ... Nature neuroscience 17 (1), 131-143, 2014 | 2487 | 2014 |
| The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases S Krasemann, C Madore, R Cialic, C Baufeld, N Calcagno, R El Fatimy, ... Immunity 47 (3), 566-581. e9, 2017 | 1985 | 2017 |
| Microglia function in the central nervous system during health and neurodegeneration M Colonna, O Butovsky Annual review of immunology 35, 441-468, 2017 | 1865 | 2017 |
| Depletion of microglia and inhibition of exosome synthesis halt tau propagation H Asai, S Ikezu, S Tsunoda, M Medalla, J Luebke, T Haydar, B Wolozin, ... Nature neuroscience 18 (11), 1584-1593, 2015 | 1413 | 2015 |
| Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood Y Ziv, N Ron, O Butovsky, G Landa, E Sudai, N Greenberg, H Cohen, ... Nature neuroscience 9 (2), 268-275, 2006 | 1369 | 2006 |
| Microglia activated by IL-4 or IFN-γ differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells O Butovsky, Y Ziv, A Schwartz, G Landa, AE Talpalar, S Pluchino, ... Molecular and Cellular Neuroscience 31 (1), 149-160, 2006 | 1057 | 2006 |
| ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy Y Shi, K Yamada, SA Liddelow, ST Smith, L Zhao, W Luo, RM Tsai, ... Nature 549 (7673), 523-527, 2017 | 978 | 2017 |
| Differential roles of microglia and monocytes in the inflamed central nervous system R Yamasaki, H Lu, O Butovsky, N Ohno, AM Rietsch, R Cialic, PM Wu, ... Journal of Experimental Medicine 211 (8), 1533-1549, 2014 | 878 | 2014 |
| TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models TR Jay, CM Miller, PJ Cheng, LC Graham, S Bemiller, ML Broihier, G Xu, ... Journal of Experimental Medicine 212 (3), 287-295, 2015 | 688 | 2015 |
| Microglial signatures and their role in health and disease O Butovsky, HL Weiner Nature Reviews Neuroscience 19 (10), 622-635, 2018 | 673 | 2018 |
| Loss of ‘homeostatic’microglia and patterns of their activation in active multiple sclerosis T Zrzavy, S Hametner, I Wimmer, O Butovsky, HL Weiner, H Lassmann Brain 140 (7), 1900-1913, 2017 | 579 | 2017 |
| Microglia states and nomenclature: A field at its crossroads RC Paolicelli, A Sierra, B Stevens, ME Tremblay, A Aguzzi, B Ajami, I Amit, ... Neuron 110 (21), 3458-3483, 2022 | 526 | 2022 |
| Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS O Butovsky, S Siddiqui, G Gabriely, AJ Lanser, B Dake, G Murugaiyan, ... The Journal of clinical investigation 122 (9), 3063-3087, 2012 | 506 | 2012 |
| Microglial phenotype: is the commitment reversible? M Schwartz, O Butovsky, W Brück, UK Hanisch Trends in neurosciences 29 (2), 68-74, 2006 | 504 | 2006 |
| Passive or active immunization with myelin basic protein promotes recovery from spinal cord contusion E Hauben, O Butovsky, U Nevo, E Yoles, G Moalem, E Agranov, F Mor, ... Journal of Neuroscience 20 (17), 6421-6430, 2000 | 494 | 2000 |
| Activation of microglia by aggregated β-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-γ and IL-4 render them protective O Butovsky, AE Talpalar, K Ben-Yaakov, M Schwartz Molecular and Cellular Neuroscience 29 (3), 381-393, 2005 | 482 | 2005 |
| Glatiramer acetate fights against Alzheimer’s disease by inducing dendritic-like microglia expressing insulin-like growth factor 1 O Butovsky, M Koronyo-Hamaoui, G Kunis, E Ophir, G Landa, H Cohen, ... Proceedings of the National Academy of Sciences 103 (31), 11784-11789, 2006 | 468 | 2006 |
| Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE S Parhizkar, T Arzberger, M Brendel, G Kleinberger, M Deussing, C Focke, ... Nature neuroscience 22 (2), 191-204, 2019 | 438 | 2019 |
| Dark microglia: a new phenotype predominantly associated with pathological states K Bisht, KP Sharma, C Lecours, M Gabriela Sánchez, H El Hajj, G Milior, ... Glia 64 (5), 826-839, 2016 | 372 | 2016 |
| Targeting mi R‐155 restores abnormal microglia and attenuates disease in SOD 1 mice O Butovsky, MP Jedrychowski, R Cialic, S Krasemann, G Murugaiyan, ... Annals of neurology 77 (1), 75-99, 2015 | 356 | 2015 |
michal schwartzprofessorVerified email at weizmann.ac.il
