RNA degradation by the exosome is promoted by a nuclear polyadenylation complex J LaCava, J Houseley, C Saveanu, E Petfalski, E Thompson, A Jacquier, ... Cell 121 (5), 713-724, 2005 | 1064 | 2005 |
RNA-quality control by the exosome J Houseley, J LaCava, D Tollervey Nature reviews Molecular cell biology 7 (7), 529-539, 2006 | 815 | 2006 |
Affinity proteomics reveals human host factors implicated in discrete stages of LINE-1 retrotransposition MS Taylor, J LaCava, P Mita, KR Molloy, CRL Huang, D Li, EM Adney, ... Cell 155 (5), 1034-1048, 2013 | 253 | 2013 |
The human cap-binding complex is functionally connected to the nuclear RNA exosome PR Andersen, M Domanski, MS Kristiansen, H Storvall, E Ntini, ... Nature structural & molecular biology 20 (12), 1367-1376, 2013 | 243 | 2013 |
LINE-1 protein localization and functional dynamics during the cell cycle P Mita, A Wudzinska, X Sun, J Andrade, S Nayak, DJ Kahler, S Badri, ... Elife 7, e30058, 2018 | 147 | 2018 |
Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms HL Chan, F Beckedorff, Y Zhang, J Garcia-Huidobro, H Jiang, A Colaprico, ... Nature communications 9 (1), 3377, 2018 | 129 | 2018 |
Dissection of affinity captured LINE-1 macromolecular complexes MS Taylor, I Altukhov, KR Molloy, P Mita, H Jiang, EM Adney, ... elife 7, e30094, 2018 | 87 | 2018 |
Rapid, optimized interactomic screening Z Hakhverdyan, M Domanski, LE Hough, AA Oroskar, AR Oroskar, ... Nature methods 12 (6), 553-560, 2015 | 76 | 2015 |
Improved methodology for the affinity isolation of human protein complexes expressed at near endogenous levels M Domanski, K Molloy, H Jiang, BT Chait, MP Rout, TH Jensen, J LaCava Biotechniques, 1, 2012 | 74 | 2012 |
LINE-1 expression in cancer correlates with p53 mutation, copy number alteration, and S phase checkpoint W McKerrow, X Wang, C Mendez-Dorantes, P Mita, S Cao, M Grivainis, ... Proceedings of the National Academy of Sciences 119 (8), e2115999119, 2022 | 68 | 2022 |
Targeting the CALR interactome in myeloproliferative neoplasms E Pronier, P Cifani, TR Merlinsky, KB Berman, AVH Somasundara, ... JCI insight 3 (22), e122703, 2018 | 63 | 2018 |
Affinity proteomics to study endogenous protein complexes: pointers, pitfalls, preferences and perspectives J LaCava, KR Molloy, MS Taylor, M Domanski, BT Chait, MP Rout Biotechniques 58 (3), 103-119, 2015 | 63 | 2015 |
LINE-1 ORF2p expression is nearly imperceptible in human cancers D Ardeljan, X Wang, M Oghbaie, MS Taylor, D Husband, V Deshpande, ... Mobile dna 11, 1-19, 2020 | 62 | 2020 |
Expression and detection of LINE-1 ORF-encoded proteins L Dai, J LaCava, MS Taylor, JD Boeke Mobile genetic elements 4 (3), 1034-48, 2014 | 56 | 2014 |
Characterizing ZC3H18, a multi-domain protein at the interface of RNA production and destruction decisions K Winczura, M Schmid, C Iasillo, KR Molloy, LM Harder, JS Andersen, ... Cell reports 22 (1), 44-58, 2018 | 52 | 2018 |
Structures, functions and adaptations of the human LINE-1 ORF2 protein ET Baldwin, T van Eeuwen, D Hoyos, A Zalevsky, EP Tchesnokov, ... Nature 626 (7997), 194-206, 2024 | 47 | 2024 |
Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multicancer biomarker MS Taylor, C Wu, PC Fridy, SJ Zhang, Y Senussi, JC Wolters, T Cajuso, ... Cancer discovery 13 (12), 2532-2547, 2023 | 42 | 2023 |
The Polycomb group protein CBX6 is an essential regulator of embryonic stem cell identity A Santanach, E Blanco, H Jiang, KR Molloy, M Sansó, J LaCava, L Morey, ... Nature communications 8 (1), 1235, 2017 | 42 | 2017 |
High prevalence and disease correlation of autoantibodies against p40 encoded by long interspersed nuclear elements in systemic lupus erythematosus V Carter, J LaCava, MS Taylor, SY Liang, C Mustelin, KC Ukadike, ... Arthritis & rheumatology 72 (1), 89-99, 2020 | 40 | 2020 |
Protein complex affinity capture from cryomilled mammalian cells J LaCava, H Jiang, MP Rout Journal of visualized experiments: JoVE, 54518, 2016 | 39 | 2016 |