Prati
Gerald Wertheim
Gerald Wertheim
Children's Hospital of Phildelphia
Potvrđena adresa e-pošte na email.chop.edu
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Citirano
Citirano
Godina
Identification of predictive biomarkers for cytokine release syndrome after chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia
DT Teachey, SF Lacey, PA Shaw, JJ Melenhorst, SL Maude, N Frey, ...
Cancer discovery 6 (6), 664-679, 2016
9892016
A novel doxycycline‐inducible system for the transgenic analysis of mammary gland biology
EJ Gunther, GK Belka, GBW Wertheim, J Wang, JL Hartman, RB Boxer, ...
The FASEB Journal 16 (3), 283-292, 2002
2632002
Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy
VG Bhoj, D Arhontoulis, G Wertheim, J Capobianchi, CA Callahan, ...
Blood, The Journal of the American Society of Hematology 128 (3), 360-370, 2016
2252016
CAR T-cell therapy is effective for CD19-dim B-lymphoblastic leukemia but is impacted by prior blinatumomab therapy
V Pillai, K Muralidharan, W Meng, A Bagashev, DA Oldridge, J Rosenthal, ...
Blood advances 3 (22), 3539-3549, 2019
1662019
Risk-adapted preemptive tocilizumab to prevent severe cytokine release syndrome after CTL019 for pediatric B-cell acute lymphoblastic leukemia: a prospective clinical trial
S Kadauke, RM Myers, Y Li, R Aplenc, D Baniewicz, DM Barrett, ...
Journal of Clinical Oncology 39 (8), 920-930, 2021
1372021
Humanized CD19-targeted chimeric antigen receptor (CAR) T cells in CAR-naive and CAR-exposed children and young adults with relapsed or refractory acute lymphoblastic leukemia
RM Myers, Y Li, A Barz Leahy, DM Barrett, DT Teachey, C Callahan, ...
Journal of Clinical Oncology 39 (27), 3044-3055, 2021
1082021
Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6 blockade–refractory idiopathic multicentric Castleman disease
DC Fajgenbaum, RA Langan, AS Japp, HL Partridge, SK Pierson, ...
The Journal of clinical investigation 129 (10), 4451-4463, 2019
1032019
Repeated loss of target surface antigen after immunotherapy in primary mediastinal large B cell lymphoma
H Yu, E Sotillo, C Harrington, G Wertheim, M Paessler, SL Maude, ...
American journal of hematology 92 (1), E11, 2017
1032017
A PERK–miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival
Y Bu, A Yoshida, N Chitnis, BJ Altman, F Tameire, A Oran, V Gennaro, ...
Nature cell biology 20 (1), 104-115, 2018
992018
High incidence of Philadelphia chromosome-like acute lymphoblastic leukemia in older adults with B-ALL
SK Tasian, C Hurtz, GB Wertheim, NG Bailey, MS Lim, RC Harvey, ...
Leukemia 31 (4), 981-984, 2017
952017
The Notch1 transcriptional activation domain is required for development and reveals a novel role for Notch1 signaling in fetal hematopoietic stem cells
DM Gerhardt, KV Pajcini, T D’altri, LL Tu, R Jain, L Xu, MJ Chen, ...
Genes & development 28 (6), 576-593, 2014
742014
Increased mTOR activation in idiopathic multicentric Castleman disease
DJ Arenas, K Floess, D Kobrin, RAL Pai, MB Srkalovic, MA Tamakloe, ...
Blood, The Journal of the American Society of Hematology 135 (19), 1673-1684, 2020
622020
Clinical efficacy of ruxolitinib and chemotherapy in a child with Philadelphia chromosome-like acute lymphoblastic leukemia with GOLGA5-JAK2 fusion and induction failure
YY Ding, JW Stern, TF Jubelirer, GB Wertheim, F Lin, F Chang, Z Gu, ...
Haematologica 103 (9), e427, 2018
582018
NTRK fusions identified in pediatric tumors: the frequency, fusion partners, and clinical outcome
X Zhao, C Kotch, E Fox, LF Surrey, GB Wertheim, ZW Baloch, F Lin, ...
JCO precision oncology 1, 204-214, 2021
572021
Ikaros imposes a barrier to CD8+ T cell differentiation by restricting autocrine IL-2 production
S O’Brien, RM Thomas, GB Wertheim, F Zhang, H Shen, AD Wells
The Journal of Immunology 192 (11), 5118-5129, 2014
572014
Cytosine deaminase APOBEC3A sensitizes leukemia cells to inhibition of the DNA replication checkpoint
AM Green, K Budagyan, KE Hayer, MA Reed, MR Savani, GB Wertheim, ...
Cancer research 77 (17), 4579-4588, 2017
552017
Heterogeneity of surface CD19 and CD22 expression in B lymphoblastic leukemia
J Rosenthal, AS Naqvi, M Luo, G Wertheim, M Paessler, ...
American Journal of Hematology 93 (11), E352-E355, 2018
502018
Cloning and Characterization of Hunk, a Novel Mammalian SNF1-Related Protein Kinase
HP Gardner, GBW Wertheim, SI Ha, NG Copeland, DJ Gilbert, NA Jenkins, ...
Genomics 63 (1), 46-59, 2000
502000
Developmental role of the SNF1-related kinase Hunk in pregnancy-induced changes in the mammary gland
HP Gardner, GK Belka, GBW Wertheim, JL Hartman, SI Ha, PA Gimotty, ...
Development 127 (20), 4493-4509, 2000
482000
Runx1 negatively regulates inflammatory cytokine production by neutrophils in response to Toll-like receptor signaling
DC Bellissimo, C Chen, Q Zhu, S Bagga, CT Lee, B He, GB Wertheim, ...
Blood advances 4 (6), 1145-1158, 2020
472020
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