Prati
Prof. Assaf Friedler
Naslov
Citirano
Citirano
Godina
Molecular mechanism of the interaction between MDM2 and p53
O Schon, A Friedler, M Bycroft, SMV Freund, AR Fersht
Journal of molecular biology 323 (3), 491-501, 2002
4512002
A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants
A Friedler, LO Hansson, DB Veprintsev, SMV Freund, TM Rippin, ...
Proceedings of the National Academy of Sciences 99 (2), 937-942, 2002
3462002
Studying protein–protein interactions using peptide arrays
C Katz, L Levy-Beladev, S Rotem-Bamberger, T Rito, SGD Rüdiger, ...
Chemical Society Reviews 40 (5), 2131-2145, 2011
2332011
Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium
Z Hayouka, J Rosenbluh, A Levin, S Loya, M Lebendiker, D Veprintsev, ...
Proceedings of the National Academy of Sciences 104 (20), 8316-8321, 2007
2332007
Butyrylcholinesterase attenuates amyloid fibril formation in vitro
S Diamant, E Podoly, A Friedler, H Ligumsky, O Livnah, H Soreq
Proceedings of the National Academy of Sciences 103 (23), 8628-8633, 2006
2032006
Rescue of mutants of the tumor suppressor p53 in cancer cells by a designed peptide
N Issaeva, A Friedler, P Bozko, KG Wiman, AR Fersht, G Selivanova
Proceedings of the National Academy of Sciences 100 (23), 13303-13307, 2003
1952003
The C terminus of p53 binds the N-terminal domain of MDM2
MV Poyurovsky, C Katz, O Laptenko, R Beckerman, M Lokshin, J Ahn, ...
Nature structural & molecular biology 17 (8), 982-989, 2010
1732010
Kinetic instability of p53 core domain mutants: implications for rescue by small molecules
A Friedler, DB Veprintsev, LO Hansson, AR Fersht
Journal of Biological Chemistry 278 (26), 24108-24112, 2003
1692003
Two sequence motifs from HIF-1α bind to the DNA-binding site of p53
LO Hansson, A Friedler, S Freund, S Rüdiger, AR Fersht
Proceedings of the National Academy of Sciences 99 (16), 10305-10309, 2002
1692002
Modulation of binding of DNA to the C-terminal domain of p53 by acetylation
A Friedler, DB Veprintsev, SMV Freund, KI von Glos, AR Fersht
Structure 13 (4), 629-636, 2005
1132005
Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation
D Mayer, FF Damberger, M Samarasimhareddy, M Feldmueller, ...
Nature communications 10 (1), 1261, 2019
1112019
The structure of an FF domain from human HYPA/FBP11
M Allen, A Friedler, O Schon, M Bycroft
Journal of molecular biology 323 (3), 411-416, 2002
1072002
Structural distortion of p53 by the mutation R249S and its rescue by a designed peptide: implications for “mutant conformation”
A Friedler, BS DeDecker, SMV Freund, C Blair, S Rüdiger, AR Fersht
Journal of molecular biology 336 (1), 187-196, 2004
862004
Cyclic peptide inhibitors of HIV-1 integrase derived from the LEDGF/p75 protein
Z Hayouka, M Hurevich, A Levin, H Benyamini, A Iosub, M Maes, ...
Bioorganic & medicinal chemistry 18 (23), 8388-8395, 2010
812010
Chemical synthesis and expression of the HIV‐1 Rev protein
P Siman, O Blatt, T Moyal, T Danieli, M Lebendiker, HA Lashuel, ...
ChemBioChem 12 (7), 1097-1104, 2011
802011
Agonist-induced dimer dissociation as a macromolecular step in G protein-coupled receptor signaling
J Petersen, SC Wright, D Rodríguez, P Matricon, N Lahav, A Vromen, ...
Nature communications 8 (1), 226, 2017
792017
Development of a functional backbone cyclic mimetic of the HIV-1 Tat arginine-rich motif
A Friedler, D Friedler, NW Luedtke, Y Tor, A Loyter, C Gilon
Journal of biological chemistry 275 (31), 23783-23789, 2000
792000
Backbone cyclic peptide, which mimics the nuclear localization signal of human immunodeficiency virus type 1 matrix protein, inhibits nuclear import and virus production in …
A Friedler, N Zakai, O Karni, YC Broder, L Baraz, M Kotler, A Loyter, ...
Biochemistry 37 (16), 5616-5622, 1998
791998
Binding of p53-derived ligands to MDM2 induces a variety of long range conformational changes
O Schon, A Friedler, S Freund, AR Fersht
Journal of molecular biology 336 (1), 197-202, 2004
782004
Observation of signal transduction in three-dimensional domain swapping
JWH Schymkowitz, F Rousseau, HR Wilkinson, A Friedler, LS Itzhaki
nature structural biology 8 (10), 888-892, 2001
762001
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Članci 1–20