A. Sloan Devlin
A. Sloan Devlin
Associate Professor, Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Potvrđena adresa e-pošte na - Početna stranica
Diet rapidly and reproducibly alters the human gut microbiome
LA David, CF Maurice, RN Carmody, DB Gootenberg, JE Button, ...
Nature 505 (7484), 559-563, 2014
Bile acid metabolites control TH17 and Treg cell differentiation
S Hang, D Paik, L Yao, E Kim, J Trinath, J Lu, S Ha, BN Nelson, SP Kelly, ...
Nature 576 (7785), 143-148, 2019
A biosynthetic pathway for a prominent class of microbiota-derived bile acids
AS Devlin, MA Fischbach
Nature chemical biology 11 (9), 685-690, 2015
Modulation of a circulating uremic solute via rational genetic manipulation of the gut microbiota
AS Devlin, A Marcobal, D Dodd, S Nayfach, N Plummer, T Meyer, ...
Cell host & microbe 20 (6), 709-715, 2016
A selective gut bacterial bile salt hydrolase alters host metabolism
L Yao, SC Seaton, S Ndousse-Fetter, AA Adhikari, N DiBenedetto, ...
Elife 7, 2018
δ-Sultone Formation Through Rh-Catalyzed C− H Insertion
SA Wolckenhauer, AS Devlin, J Du Bois
Organic Letters 9 (21), 4363-4366, 2007
Human gut bacteria produce ΤΗ17-modulating bile acid metabolites
D Paik, L Yao, Y Zhang, S Bae, GD D’Agostino, M Zhang, E Kim, ...
Nature 603 (7903), 907-912, 2022
Bariatric surgery reveals a gut-restricted TGR5 agonist with anti-diabetic effects
SN Chaudhari, DA Harris, H Aliakbarian, JN Luo, MT Henke, ...
Nature chemical biology 17 (1), 20-29, 2021
A bacterial bile acid metabolite modulates Treg activity through the nuclear hormone receptor NR4A1
W Li, S Hang, Y Fang, S Bae, Y Zhang, M Zhang, G Wang, MD McCurry, ...
Cell Host & Microbe 29 (9), 1366-1377. e9, 2021
Development of a covalent inhibitor of gut bacterial bile salt hydrolases
AA Adhikari, T Seegar, SB Ficarro, MD McCurry, D Ramachandran, L Yao, ...
Nature chemical biology 16 (3), 318-326, 2020
A microbial metabolite remodels the gut-liver axis following bariatric surgery
SN Chaudhari, JN Luo, DA Harris, H Aliakbarian, L Yao, D Paik, ...
Cell host & microbe 29 (3), 408-424. e7, 2021
Modular synthesis of the pentacyclic core of batrachotoxin and select batrachotoxin analogue designs
AS Devlin, J Du Bois
Chemical science 4 (3), 1059-1063, 2013
Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling
KM Schneider, LS Candels, JR Hov, M Myllys, R Hassan, CV Schneider, ...
Nature Metabolism 3 (9), 1228-1241, 2021
Inhibition of sodium ion channel function with truncated forms of batrachotoxin
T Toma, MM Logan, F Menard, AS Devlin, J Du Bois
ACS chemical neuroscience 7 (10), 1463-1468, 2016
Chains of evidence from correlations to causal molecules in microbiome-linked diseases
SN Chaudhari, MD McCurry, AS Devlin
Nature Chemical Biology 17 (10), 1046-1056, 2021
A gut-restricted lithocholic acid analog as an inhibitor of gut bacterial bile salt hydrolases
AA Adhikari, D Ramachandran, SN Chaudhari, CE Powell, W Li, ...
ACS Chemical Biology 16 (8), 1401-1412, 2021
Author Correction: Bile acid metabolites control TH 17 and T reg cell differentiation
S Hang, D Paik, L Yao, E Kim, J Trinath, J Lu, S Ha, BN Nelson, SP Kelly, ...
Nature 579 (7798), E7, 2020
Intestinal Co-culture System to Study TGR5 Agonism and Gut Restriction
SN Chaudhari, AS Devlin
Bio-protocol 11 (6), e3948-e3948, 2021
Bile acid metabolites control Th17 and Treg cell differentiation
S Hang, D Paik, L Yao, T Jamma, J Lu, S Ha, BN Nelson, SP Kelly, L Wu, ...
The Journal of Immunology 204 (1 Supplement), 230.6-230.6, 2020
Batrachotoxin analogues, compositions, uses, and preparation thereof
J Du Bois, AS Devlin, MM Logan, F Menard, T Toma
US Patent 9,090,627, 2015
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