Gregory J. Cost
Gregory J. Cost
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Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR‐mediated gene disruption and other …
C Baker Brachmann, A Davies, GJ Cost, E Caputo, J Li, P Hieter, ...
Yeast 14 (2), 115-132, 1998
A TALE nuclease architecture for efficient genome editing
JC Miller, S Tan, G Qiao, KA Barlow, J Wang, DF Xia, X Meng, ...
Nature biotechnology 29 (2), 143-148, 2011
Genetic engineering of human ES and iPS cells using TALE nucleases
D Hockemeyer, H Wang, S Kiani, CS Lai, Q Gao, JP Cassady, GJ Cost, ...
Nature biotechnology 29 (8), 731, 0
Knockout rats via embryo microinjection of zinc-finger nucleases
AM Geurts, GJ Cost, Y Freyvert, B Zeitler, JC Miller, VM Choi, SS Jenkins, ...
Science 325 (5939), 433, 2009
Knockout rats generated by embryo microinjection of TALENs
L Tesson, C Usal, S Ménoret, E Leung, BJ Niles, S Remy, Y Santiago, ...
Nature biotechnology 29 (8), 695-696, 2011
Human L1 element target‐primed reverse transcription in vitro
GJ Cost, Q Feng, A Jacquier, JD Boeke
The EMBO journal, 2002
Human l1 retrotransposition is associated with genetic instability in vivo
DE Symer, C Connelly, ST Szak, EM Caputo, GJ Cost, G Parmigiani, ...
Cell 110 (3), 327-338, 2002
Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases
J Hauschild, B Petersen, Y Santiago, AL Queisser, JW Carnwath, ...
Proceedings of the National Academy of Sciences 108 (29), 12013-12017, 2011
Translating dosage compensation to trisomy 21
J Jiang, Y Jing, GJ Cost, JC Chiang, HJ Kolpa, AM Cotton, DM Carone, ...
Nature 500 (7462), 296-300, 2013
Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells
MD Hoban, GJ Cost, MC Mendel, Z Romero, ML Kaufman, AV Joglekar, ...
Blood, The Journal of the American Society of Hematology 125 (17), 2597-2604, 2015
Targeting of human retrotransposon integration is directed by the specificity of the L1 endonuclease for regions of unusual DNA structure
GJ Cost, JD Boeke
Biochemistry 37 (51), 18081-18093, 1998
Targeted genomic modification with partially single-stranded donor molecules
GJ Cost, DM Guschin, F Urnov
US Patent 9,255,259, 2016
Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology
SJ Orlando, Y Santiago, RC DeKelver, Y Freyvert, EA Boydston, ...
Nucleic acids research 38 (15), e152-e152, 2010
In vivo cleavage of transgene donors promotes nuclease‐mediated targeted integration
S Cristea, Y Freyvert, Y Santiago, MC Holmes, FD Urnov, PD Gregory, ...
Biotechnology and bioengineering 110 (3), 871-880, 2013
Sequence-directed DNA translocation by purified FtsK
PJ Pease, O Levy, GJ Cost, J Gore, JL Ptacin, D Sherratt, C Bustamante, ...
Science 307 (5709), 586-590, 2005
Highly efficient deletion of FUT8 in CHO cell lines using zinc‐finger nucleases yields cells that produce completely nonfucosylated antibodies
L Malphettes, Y Freyvert, J Chang, PQ Liu, E Chan, JC Miller, Z Zhou, ...
Biotechnology and bioengineering 106 (5), 774-783, 2010
Targeted genomic modification with partially single-stranded donor molecules
GJ Cost, DM Guschin, F Urnov
US Patent 9,005,973, 2015
Methods and compositions for treatment of a genetic condition
A Conway, GJ Cost, R DeKelver, EJ Rebar, A Reik, F Urnov, J Wang, ...
US Patent 9,873,894, 2018
Methods and compositions for nuclease-mediated targeted integration of transgenes
GJ Cost, F Urnov, WM AINLEY, JF Petolino, JP Samuel, SR Webb, ...
US Patent 10,174,331, 2019
BAK and BAX deletion using zinc‐finger nucleases yields apoptosis‐resistant CHO cells
GJ Cost, Y Freyvert, A Vafiadis, Y Santiago, JC Miller, E Rebar, ...
Biotechnology and bioengineering 105 (2), 330-340, 2010
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