CD133+ brain tumor-initiating cells are dependent on STAT3 signaling to drive medulloblastoma recurrence N Garg, D Bakhshinyan, C Venugopal, S Mahendram, DA Rosa, ... Oncogene 36 (5), 606-617, 2017 | 67 | 2017 |
STAT3 pathway regulates lung-derived brain metastasis initiating cell capacity through miR-21 activation M Singh, N Garg, C Venugopal, R Hallett, T Tokar, N McFarlane, ... Oncotarget 6 (29), 27461, 2015 | 65 | 2015 |
Carbon–carbon bond-forming reactions of α-carbonyl carbocations: exploration of a reversed-polarity equivalent of enolate chemistry PS Lai, JA Dubland, MG Sarwar, MG Chudzinski, MS Taylor Tetrahedron 67 (39), 7586-7592, 2011 | 65 | 2011 |
A STAT inhibitor patent review: progress since 2011 PS Lai, DA Rosa, A Magdy Ali, RF Gómez-Biagi, DP Ball, AE Shouksmith, ... Expert opinion on therapeutic patents 25 (12), 1397-1421, 2015 | 61 | 2015 |
Applying small molecule signal transducer and activator of transcription-3 (STAT3) protein inhibitors as pancreatic cancer therapeutics CC Arpin, S Mac, Y Jiang, H Cheng, M Grimard, BDG Page, MM Kamocka, ... Molecular cancer therapeutics 15 (5), 794-805, 2016 | 39 | 2016 |
Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)‐Resistant CML Lines While Circumventing Pharmacokinetic Liabilities AM Ali, RF Gómez‐Biagi, DA Rosa, PS Lai, WL Heaton, JS Park, ... ChemMedChem 11 (8), 850-861, 2016 | 37 | 2016 |
Preparation of substituted oxazoles by Ritter reactions of α-oxo tosylates PS Lai, MS Taylor Synthesis 2010 (09), 1449-1452, 2010 | 28 | 2010 |
Directed ortho metalation-boronation Suzuki-Miyaura cross coupling leading to synthesis of azafluorenol core liquid crystals PS Lai | 2 | 2007 |
A STAT inhibitor patent review: progress since 2011 (vol 25, pg 1397, 2015) PS Lai, DA Rosa, MA Ali, RF Gomez-Biagi, DP Ball, AE Shouksmith, ... EXPERT OPINION ON THERAPEUTIC PATENTS 25 (12), 1495-1495, 2015 | | 2015 |
Developing Inhibitors of STAT3: Targeting Downstream of the Kinases for Treating Disease AM Lewis, DP Ball, R Rana, JS Park, D Rosa, PS Lai, RF Gómez-Biagi, ... Kinomics: Approaches and Applications, 2015 | | 2015 |
a-keto Carbocations-Umpolung of enolate reactivity for the construction of CC and CN bonds PS Lai, J Dubland, MG Sarwar, MS Taylor ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 242, 2011 | | 2011 |
Department of Chemistry, University of Toronto, 80 St. George St., Toronto, ON M5S 3H6 Canada PS Lai, JA Dubland, MG Sarwar, MG Chudzinski, MS Taylor | | 2011 |
Applications of α-Keto Carbocations in Carbon-Carbon and Carbon-Nitrogen Bond Formation PS Lai | | 2011 |
In-Situ Directed Ortho Metalation (DoM)-Boronation Suzuki-Miyaura Cross Coupling of Pyridine Derivatives M Alessi, A Larkin, L Green, K Ogilvie, S Lai, S Lopez, V Snieckus Journal of Organic Chemistry 72, 3199, 2007 | | 2007 |