Alimentary Pharmabiotic Centre, University College Cork, Ireland
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Acute colitis induced by dextran sulfate sodium progresses to chronicity in C57BL/6 but not in BALB/c mice: correlation between symptoms and inflammation
S Melgar, A Karlsson, E Michaëlsson
American Journal of Physiology-Gastrointestinal and Liver Physiology 288 (6 …, 2005
Paradoxical coexpression of proinflammatory and down-regulatory cytokines in intestinal T cells in childhood celiac disease
G Forsberg, O Hernell, S Melgar, A Israelsson, S Hammarström, ...
Gastroenterology 123 (3), 667-678, 2002
Validation of murine dextran sulfate sodium-induced colitis using four therapeutic agents for human inflammatory bowel disease
S Melgar, L Karlsson, E Rehnström, A Karlsson, H Utkovic, L Jansson, ...
International immunopharmacology 8 (6), 836-844, 2008
Over‐expression of interleukin 10 in mucosal T cells of patients with active ulcerative colitis
S Melgar, MMW Yeung, A Bas, G Forsberg, O Suhr, Å Öberg, ...
Clinical & Experimental Immunology 134 (1), 127-137, 2003
Intraepithelial lymphocytes in human gut have lytic potential and a cytokine profile that suggest T helper 1 and cytotoxic functions.
C Lundqvist, S Melgar, MM Yeung, S Hammarström, ML Hammarström
The Journal of Immunology 157 (5), 1926-1934, 1996
Characterisation of mucosal lymphoid aggregates in ulcerative colitis: immune cell phenotype and TcR-γδ expression
MMW Yeung, S Melgar, V Baranov, Å Öberg, Å Danielsson, ...
Gut 47 (2), 215-227, 2000
The impact of western diet and nutrients on the microbiota and immune response at mucosal interfaces
D Statovci, M Aguilera, J MacSharry, S Melgar
Frontiers in immunology 8, 838, 2017
Induction and activation of adaptive immune populations during acute and chronic phases of a murine model of experimental colitis
LJ Hall, E Faivre, A Quinlan, F Shanahan, K Nally, S Melgar
Digestive diseases and sciences 56 (1), 79-89, 2011
Pattern recognition receptors—molecular orchestrators of inflammation in inflammatory bowel disease
D Walsh, J McCarthy, C O’Driscoll, S Melgar
Cytokine & growth factor reviews 24 (2), 91-104, 2013
Intestinal delivery of non-viral gene therapeutics: physiological barriers and preclinical models
MJ O’Neill, L Bourre, S Melgar, CM O’Driscoll
Drug discovery today 16 (5-6), 203-218, 2011
Mechanism of protection of transepithelial barrier function by Lactobacillus salivarius: strain dependence and attenuation by bacteriocin production
E Miyauchi, J O'Callaghan, LF Buttó, G Hurley, S Melgar, S Tanabe, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 303 (9 …, 2012
Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis
S Yang, B Wang, F Humphries, R Jackson, ME Healy, R Bergin, G Aviello, ...
Nature immunology 14 (9), 927-936, 2013
Magnetic resonance imaging of experimental mouse colitis and association with inflammatory activity
AE Larsson, S Melgar, E Rehnström, E Michaëlsson, L Svensson, ...
Inflammatory bowel diseases 12 (6), 478-485, 2006
Psychological stress reactivates dextran sulfate sodium-induced chronic colitis in mice
S Melgar, K Engström, Å Jägervall, V Martinez
Stress 11 (5), 348-362, 2008
A novel effect of DMOG on cell metabolism: direct inhibition of mitochondrial function precedes HIF target gene expression
AV Zhdanov, IA Okkelman, FWJ Collins, S Melgar, DB Papkovsky
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1847 (10), 1254-1266, 2015
Local production of chemokines and prostaglandin E2 in the acute, chronic and recovery phase of murine experimental colitis
S Melgar, M Drmotova, E Rehnström, L Jansson, E Michaëlsson
Cytokine 35 (5-6), 275-283, 2006
IL-36α expression is elevated in ulcerative colitis and promotes colonic inflammation
SE Russell, RM Horan, AM Stefanska, A Carey, G Leon, M Aguilera, ...
Mucosal immunology 9 (5), 1193-1204, 2016
Gene silencing of TNF-alpha in a murine model of acute colitis using a modified cyclodextrin delivery system
J McCarthy, MJ O'neill, L Bourre, D Walsh, A Quinlan, G Hurley, J Ogier, ...
Journal of controlled release 168 (1), 28-34, 2013
Mice with experimental colitis show an altered metabolism with decreased metabolic rate
S Melgar, M Bjursell, AK Gerdin, L Svensson, E Michaëlsson, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 292 (1 …, 2007
Natural killer cells protect mice from DSS-induced colitis by regulating neutrophil function via the NKG2A receptor
LJ Hall, CT Murphy, A Quinlan, G Hurley, F Shanahan, K Nally, S Melgar
Mucosal immunology 6 (5), 1016-1026, 2013
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