| A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling J Wysocka, T Swigut, H Xiao, TA Milne, SY Kwon, J Landry, M Kauer, ... Nature 442 (7098), 86-90, 2006 | 1443 | 2006 |
| MLL targets SET domain methyltransferase activity to Hox gene promoters TA Milne, SD Briggs, HW Brock, ME Martin, D Gibbs, CD Allis, JL Hess Molecular cell 10 (5), 1107-1117, 2002 | 1266 | 2002 |
| WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development J Wysocka, T Swigut, TA Milne, Y Dou, X Zhang, AL Burlingame, ... Cell 121 (6), 859-872, 2005 | 960 | 2005 |
| Regulation of MLL1 H3K4 methyltransferase activity by its core components Y Dou, TA Milne, AJ Ruthenburg, S Lee, JW Lee, GL Verdine, CD Allis, ... Nature structural & molecular biology 13 (8), 713-719, 2006 | 864 | 2006 |
| Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF Y Dou, TA Milne, AJ Tackett, ER Smith, A Fukuda, J Wysocka, CD Allis, ... Cell 121 (6), 873-885, 2005 | 788 | 2005 |
| Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus CM Hughes, O Rozenblatt-Rosen, TA Milne, TD Copeland, SS Levine, ... Molecular cell 13 (4), 587-597, 2004 | 725 | 2004 |
| RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells J Kim, M Guermah, RK McGinty, JS Lee, Z Tang, TA Milne, A Shilatifard, ... Cell 137 (3), 459-471, 2009 | 592 | 2009 |
| Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors TA Milne, CM Hughes, R Lloyd, Z Yang, O Rozenblatt-Rosen, Y Dou, ... Proceedings of the National Academy of Sciences 102 (3), 749-754, 2005 | 532 | 2005 |
| Hoxa9 and Meis1 Are Key Targets for MLL-ENL-Mediated Cellular Immortalization BB Zeisig, T Milne, MP García-Cuéllar, S Schreiner, ME Martin, U Fuchs, ... Molecular and cellular biology 24 (2), 617-628, 2004 | 398 | 2004 |
| Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions AJ Ruthenburg, H Li, TA Milne, S Dewell, RK McGinty, M Yuen, ... Cell 145 (5), 692-706, 2011 | 393 | 2011 |
| Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia A Akalin, FE Garrett-Bakelman, M Kormaksson, J Busuttil, L Zhang, ... PLoS genetics 8 (6), e1002781, 2012 | 329 | 2012 |
| Regulation of hippocampal H3 histone methylation by acute and chronic stress RG Hunter, KJ McCarthy, TA Milne, DW Pfaff, BS McEwen Proceedings of the National Academy of Sciences 106 (49), 20912-20917, 2009 | 322 | 2009 |
| Intragenic enhancers act as alternative promoters MS Kowalczyk, JR Hughes, D Garrick, MD Lynch, JA Sharpe, ... Molecular cell 45 (4), 447-458, 2012 | 313 | 2012 |
| MLL associates specifically with a subset of transcriptionally active target genes TA Milne, Y Dou, ME Martin, HW Brock, RG Roeder, JL Hess Proceedings of the National Academy of Sciences 102 (41), 14765-14770, 2005 | 277 | 2005 |
| Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis TA Milne, J Kim, GG Wang, SC Stadler, V Basrur, SJ Whitcomb, Z Wang, ... Molecular cell 38 (6), 853-863, 2010 | 246 | 2010 |
| Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression Z Wang, J Song, TA Milne, GG Wang, H Li, CD Allis, DJ Patel Cell 141 (7), 1183-1194, 2010 | 238 | 2010 |
| Leukemogenic MLL fusion proteins bind across a broad region of the Hox a9 locus, promoting transcription and multiple histone modifications TA Milne, ME Martin, HW Brock, RK Slany, JL Hess Cancer research 65 (24), 11367-11374, 2005 | 230 | 2005 |
| MLL-AF9 expression in hematopoietic stem cells drives a highly invasive AML expressing EMT-related genes linked to poor outcome V Stavropoulou, S Kaspar, L Brault, MA Sanders, S Juge, S Morettini, ... Cancer cell 30 (1), 43-58, 2016 | 215 | 2016 |
| Interaction of MLL amino terminal sequences with menin is required for transformation C Caslini, Z Yang, M El-Osta, TA Milne, RK Slany, JL Hess Cancer research 67 (15), 7275-7283, 2007 | 210 | 2007 |
| Metabolic gatekeeper function of B-lymphoid transcription factors LN Chan, Z Chen, D Braas, JW Lee, G Xiao, H Geng, KN Cosgun, C Hurtz, ... Nature 542 (7642), 479-483, 2017 | 208 | 2017 |
Robert RoederProfessor of Biochemistry and Molecular Biology, The Rockefeller UniversityVerified email at rockefeller.edu
