Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2, 3-dioxygenase inhibitory compound D-1-methyl-tryptophan R Metz, JB DuHadaway, U Kamasani, L Laury-Kleintop, AJ Muller, ... Cancer research 67 (15), 7082-7087, 2007 | 602 | 2007 |
Indoleamine 2, 3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer GC Prendergast, C Smith, S Thomas, L Mandik-Nayak, L Laury-Kleintop, ... Cancer immunology, immunotherapy 63, 721-735, 2014 | 519 | 2014 |
IDO is a nodal pathogenic driver of lung cancer and metastasis development C Smith, MY Chang, KH Parker, DW Beury, JB DuHadaway, HE Flick, ... Cancer discovery 2 (8), 722-735, 2012 | 342 | 2012 |
Inflammatory reprogramming with IDO1 inhibitors: turning immunologically unresponsive ‘cold’tumors ‘hot’ GC Prendergast, A Mondal, S Dey, LD Laury-Kleintop, AJ Muller Trends in cancer 4 (1), 38-58, 2018 | 155 | 2018 |
RhoB regulates PDGFR-β trafficking and signaling in vascular smooth muscle cells M Huang, JB DuHadaway, GC Prendergast, LD Laury-Kleintop Arteriosclerosis, thrombosis, and vascular biology 27 (12), 2597-2605, 2007 | 84 | 2007 |
Cholesterol, calcium and atherosclerosis: is there a role for calcium channel blockers in atheroprotection? TN Tulenko, L Laury-Kleintop, MF Walter, RP Mason International journal of cardiology 62, S55-S66, 1997 | 79 | 1997 |
The SOCS3-independent expression of IDO2 supports the homeostatic generation of T regulatory cells by human dendritic cells S Trabanelli, D Očadlíková, M Ciciarello, V Salvestrini, M Lecciso, ... The Journal of Immunology 192 (3), 1231-1240, 2014 | 75 | 2014 |
The exon-intron organization of the human erythrocyte α-spectrin gene L Kotula, LD Laury-Kleintop, L Showe, K Sahr, AJ Linnenbach, B Forget, ... Genomics 9 (1), 131-140, 1991 | 57 | 1991 |
Cardiac and gastrointestinal liabilities caused by deficiency in the immune modulatory enzyme indoleamine 2, 3-dioxygenase MY Chang, C Smith, JB DuHadaway, JR Pyle, J Boulden, AP Soler, ... Cancer biology & therapy 12 (12), 1050-1058, 2011 | 56 | 2011 |
IDO is a nodal pathogenic driver of lung cancer and metastasis development. Cancer Discov. 2012; 2: 722–735. doi: 10.1158/2159-8290 C Smith, MY Chang, KH Parker, DW Beury, JB DuHadaway, HE Flick, ... CD-12-0014.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 50 | |
RhoB links PDGF signaling to cell migration by coordinating activation and localization of Cdc42 and Rac M Huang, L Satchell, JB DuHadaway, GC Prendergast, ... Journal of cellular biochemistry 112 (6), 1572-1584, 2011 | 48 | 2011 |
Reduction of the expression of the late-onset Alzheimer’s disease (AD) risk-factor BIN1 does not affect amyloid pathology in an AD mouse model RJ Andrew, P De Rossi, P Nguyen, HR Kowalski, AJ Recupero, ... Journal of Biological Chemistry 294 (12), 4477-4487, 2019 | 47 | 2019 |
The smooth muscle cell membrane during atherogenesis: a potential target for amlodipine in atheroprotection TN Tulenko, AE Sumner, M Chen, Y Huang, L Laury-Kleintop, ... American Heart Journal 141 (2), S1-S11, 2001 | 47 | 2001 |
Therapeutic antibody targeting of indoleamine-2, 3-dioxygenase (IDO2) inhibits autoimmune arthritis LMF Merlo, S Grabler, JB DuHadaway, E Pigott, K Manley, ... Clinical Immunology 179, 8-16, 2017 | 46 | 2017 |
The select cyclooxygenase-2 inhibitor celecoxib reduced the extent of atherosclerosis in apo E-/-mice S Jacob, L Laury-Kleintop, S Lanza-Jacoby Journal of Surgical Research 146 (1), 135-142, 2008 | 46 | 2008 |
Discovery of a human peptide sequence signaling islet neogenesis CS Levetan, LV Upham, S Deng, L Laury-Kleintop, V Kery, R Nolan, ... Endocrine Practice 14 (9), 1075-1083, 2008 | 41 | 2008 |
Stromal cyclin D1 promotes heterotypic immune signaling and breast cancer growth TG Pestell, X Jiao, M Kumar, AR Peck, M Prisco, S Deng, Z Li, A Ertel, ... Oncotarget 8 (47), 81754, 2017 | 38 | 2017 |
Compartmentalization of hnRNP‐K during cell cycle progression and its interaction with calponin in the cytoplasm LD Laury‐Kleintop, M Tresini, O Hammond Journal of cellular biochemistry 95 (5), 1042-1056, 2005 | 37 | 2005 |
Celecoxib combined with atorvastatin prevents progression of atherosclerosis M Raval, PG Frank, L Laury-Kleintop, G Yan, S Lanza-Jacoby Journal of Surgical Research 163 (2), e113-e122, 2010 | 34 | 2010 |
Suprabasal induction of ornithine decarboxylase in adult mouse skin is sufficient to activate keratinocytes L Lan, CS Hayes, L Laury-Kleintop, SK Gilmour Journal of investigative dermatology 124 (3), 602-614, 2005 | 34 | 2005 |