Antony Rosen
Antony Rosen
Mary Betty Stevens Professor of Medicine, Johns Hopkins
Verified email at jhmi.edu
Title
Cited by
Cited by
Year
Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes.
LA Casciola-Rosen, G Anhalt, A Rosen
Journal of Experimental Medicine 179 (4), 1317-1330, 1994
18691994
Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death.
L Casciola-Rosen, DW Nicholson, T Chong, KR Rowan, NA Thornberry, ...
The Journal of experimental medicine 183 (5), 1957-1964, 1996
7211996
Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity
L Casciola-Rosen, F Andrade, D Ulanet, WB Wong, A Rosen
The Journal of experimental medicine 190 (6), 815-826, 1999
5621999
Autoantibodies against 3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase in patients with statin‐associated autoimmune myopathy
AL Mammen, T Chung, L Christopher‐Stine, P Rosen, A Rosen, ...
Arthritis & Rheumatism 63 (3), 713-721, 2011
5172011
Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus
L Casciola-Rosen, A Rosen, M Petri, M Schlissel
Proceedings of the National Academy of Sciences 93 (4), 1624-1629, 1996
5161996
Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset
R Goldbach-Mansky, J Lee, A McCoy, J Hoxworth, C Yarboro, JS Smolen, ...
Arthritis Research & Therapy 2 (3), 236, 2000
5052000
Specific cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death.
LA Casciola-Rosen, DK Miller, GJ Anhalt, A Rosen
Journal of Biological Chemistry 269 (49), 30757-30760, 1994
5031994
DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis.
LA Casciola-Rosen, GJ Anhalt, A Rosen
The Journal of experimental medicine 182 (6), 1625-1634, 1995
5011995
The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling
M Mancini, DW Nicholson, S Roy, NA Thornberry, EP Peterson, ...
The Journal of cell biology 140 (6), 1485-1495, 1998
4891998
Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis
M Mancini, CE Machamer, S Roy, DW Nicholson, NA Thornberry, ...
The Journal of cell biology 149 (3), 603-612, 2000
4462000
Autoantigens as substrates for apoptotic proteases: implications for the pathogenesis of systemic autoimmune disease
A Rosen, L Casciola-Rosen
Cell Death & Differentiation 6 (1), 6-12, 1999
4141999
Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane
M Thelen, A Rosen, AC Nairn, A Aderem
Nature 351 (6324), 320-322, 1991
3911991
Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis
F Andrade, S Roy, D Nicholson, N Thornberry, A Rosen, ...
Immunity 8 (4), 451-460, 1998
3881998
The mucocutaneous and systemic phenotype of dermatomyositis patients with antibodies to MDA5 (CADM-140): a retrospective study
D Fiorentino, L Chung, J Zwerner, A Rosen, L Casciola-Rosen
Journal of the American Academy of Dermatology 65 (1), 25-34, 2011
3502011
Enhanced autoantigen expression in regenerating muscle cells in idiopathic inflammatory myopathy
L Casciola-Rosen, K Nagaraju, P Plotz, K Wang, S Levine, E Gabrielson, ...
Journal of Experimental Medicine 201 (4), 591-601, 2005
3392005
Hsp60 accelerates the maturation of pro‐caspase‐3 by upstream activator proteases during apoptosis
S Xanthoudakis, S Roy, D Rasper, T Hennessey, Y Aubin, R Cassady, ...
The EMBO journal 18 (8), 2049-2056, 1999
3351999
Histidyl–tRNA synthetase and asparaginyl–tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells
OMZ Howard, HF Dong, D Yang, N Raben, K Nagaraju, A Rosen, ...
The Journal of experimental medicine 196 (6), 781-791, 2002
2972002
Association of the autoimmune disease scleroderma with an immunologic response to cancer
CG Joseph, E Darrah, AA Shah, AD Skora, LA Casciola-Rosen, ...
Science 343 (6167), 152-157, 2014
2882014
Activation of the endoplasmic reticulum stress response in autoimmune myositis: potential role in muscle fiber damage and dysfunction
K Nagaraju, L Casciola‐Rosen, I Lundberg, R Rawat, S Cutting, ...
Arthritis & Rheumatism 52 (6), 1824-1835, 2005
2862005
Novel packages of viral and self-antigens are generated during apoptosis.
A Rosen, L Casciola-Rosen, J Ahearn
The Journal of experimental medicine 181 (4), 1557-1561, 1995
2781995
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