Professor, School of Life Sciences, The Chinese University of Hong Kong
Potvrđena adresa e-pošte na - Početna stranica
Immunomodulatory and anti-SARS activities of Houttuynia cordata
KM Lau, KM Lee, CM Koon, CSF Cheung, CP Lau, HM Ho, MYH Lee, ...
Journal of ethnopharmacology 118 (1), 79-85, 2008
Hot-spot mutants of p53 core domain evince characteristic local structural changes
KB Wong, BS DeDecker, SMV Freund, MR Proctor, M Bycroft, AR Fersht
Proceedings of the National Academy of Sciences 96 (15), 8438-8442, 1999
Protein folding from a highly disordered denatured state: the folding pathway of chymotrypsin inhibitor 2 at atomic resolution
SL Kazmirski, KB Wong, SMV Freund, YJ Tan, AR Fersht, V Daggett
Proceedings of the National Academy of Sciences 98 (8), 4349-4354, 2001
Towards a complete description of the structural and dynamic properties of the denatured state of barnase and the role of residual structure in folding
KB Wong, J Clarke, CJ Bond, JL Neira, SMV Freund, AR Fersht, ...
Journal of molecular biology 296 (5), 1257-1282, 2000
Mechanism of rescue of common p53 cancer mutations by second‐site suppressor mutations
PV Nikolova, KB Wong, B DeDecker, J Henckel, AR Fersht
The EMBO journal, 2000
Expression and functional study of estrogen receptor-related receptors in human prostatic cells and tissues
CP Cheung, S Yu, KB Wong, LW Chan, FMM Lai, X Wang, M Suetsugi, ...
The Journal of Clinical Endocrinology & Metabolism 90 (3), 1830-1844, 2005
Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis
R Pang, TKW Lee, RTP Poon, ST Fan, KB Wong, YL Kwong, E Tse
Gastroenterology 132 (3), 1088-1103, 2007
Recent advances in trichosanthin, a ribosome-inactivating protein with multiple pharmacological properties
PC Shaw, KM Lee, KB Wong
Toxicon 45 (6), 683-689, 2005
Characterization of residual structure in the thermally denatured state of barnase by simulation and experiment: description of the folding pathway
CJ Bond, KB Wong, J Clarke, AR Fersht, V Daggett
Proceedings of the National Academy of Sciences 94 (25), 13409-13413, 1997
Cold denaturation of barstar: 1H, 15N and13C NMR assignment and characterisation of residual structure
KB Wong, SMV Freund, AR Fersht
Journal of molecular biology 259 (4), 805-818, 1996
Structure of UreG/UreF/UreH Complex Reveals How Urease Accessory Proteins Facilitate Maturation of Helicobacter pylori Urease
YH Fong, HC Wong, MH Yuen, PH Lau, YW Chen, KB Wong
PLoS biology 11 (10), e1001678, 2013
Stabilizing salt-bridge enhances protein thermostability by reducing the heat capacity change of unfolding
CH Chan, TH Yu, KB Wong
PloS one 6 (6), e21624, 2011
Design, synthesis and crystallographic analysis of nitrile-based broad-spectrum peptidomimetic inhibitors for coronavirus 3C-like proteases
CP Chuck, C Chen, Z Ke, DCC Wan, HF Chow, KB Wong
European journal of medicinal chemistry 59, 1-6, 2013
Initiation sites of protein folding by NMR analysis.
SM Freund, KB Wong, AR Fersht
Proceedings of the National Academy of Sciences 93 (20), 10600-10603, 1996
A rigidifying salt-bridge favors the activity of thermophilic enzyme at high temperatures at the expense of low-temperature activity
SY Lam, RCY Yeung, TH Yu, KH Sze, KB Wong
PLoS biology 9 (3), e1001027, 2011
Profiling of substrate specificities of 3C-like proteases from group 1, 2a, 2b, and 3 coronaviruses
CP Chuck, HF Chow, DCC Wan, KB Wong
PloS one 6 (11), e27228, 2011
Profiling of substrate specificity of SARS-CoV 3CLpro
CP Chuck, LT Chong, C Chen, HF Chow, DCC Wan, KB Wong
PloS one 5 (10), e13197, 2010
Barstar has a highly dynamic hydrophobic core: evidence from molecular dynamics simulations and nuclear magnetic resonance relaxation data
KB Wong, V Daggett
Biochemistry 37 (32), 11182-11192, 1998
Simeprevir potently suppresses SARS-CoV-2 replication and synergizes with remdesivir
HS Lo, KPY Hui, HM Lai, X He, KS Khan, S Kaur, J Huang, Z Li, ...
ACS central science 7 (5), 792-802, 2021
Interaction between trichosanthin, a ribosome-inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses
DSB Chan, LO Chu, KM Lee, PHM Too, KW Ma, KH Sze, G Zhu, PC Shaw, ...
Nucleic acids research 35 (5), 1660-1672, 2007
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