Alberto Inga
Alberto Inga
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The expanding universe of p53 targets
D Menendez, A Inga, MA Resnick
Nature reviews Cancer 9 (10), 724-737, 2009
A highly specific SpCas9 variant is identified by in vivo screening in yeast
A Casini, M Olivieri, G Petris, C Montagna, G Reginato, G Maule, ...
Nature biotechnology 36 (3), 265, 2018
Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence
A Inga, F Storici, TA Darden, MA Resnick
Molecular and cellular biology 22 (24), 8612-8625, 2002
Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity
MA Resnick, A Inga
Proceedings of the National Academy of Sciences 100 (17), 9934-9939, 2003
p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements
P Campomenosi, P Monti, A Aprile, A Abbondandolo, T Frebourg, B Gold, ...
Oncogene 20 (27), 3573-3579, 2001
The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis
B Leroy, JL Fournier, C Ishioka, P Monti, A Inga, G Fronza, T Soussi
Nucleic acids research 41 (D1), D962-D969, 2013
Noncanonical DNA motifs as transactivation targets by wild type and mutant p53
JJ Jordan, D Menendez, A Inga, M Nourredine, D Bell, MA Resnick
PLoS genetics 4 (6), e1000104, 2008
A loss-of-function mutation in the binding domain of HAND1 predicts hypoplasia of the human hearts
SM Reamon-Buettner, Y Ciribilli, A Inga, J Borlak
Human molecular genetics 17 (10), 1397-1405, 2008
The biological impact of the human master regulator p53 can be altered by mutations that change the spectrum and expression of its target genes
D Menendez, A Inga, MA Resnick
Molecular and cellular biology 26 (6), 2297-2308, 2006
The ribonucleic complex HuR-MALAT1 represses CD133 expression and suppresses epithelial–mesenchymal transition in breast cancer
E Latorre, S Carelli, I Raimondi, V D'Agostino, I Castiglioni, C Zucal, ...
Cancer research 76 (9), 2626-2636, 2016
A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network
D Menendez, O Krysiak, A Inga, B Krysiak, MA Resnick, G Schönfelder
Proceedings of the National Academy of Sciences 103 (5), 1406-1411, 2006
Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation
DJ Tomso, A Inga, D Menendez, GS Pittman, MR Campbell, F Storici, ...
Proceedings of the National Academy of Sciences 102 (18), 6431-6436, 2005
More targets, more pathways and more clues for mutant p53
S Garritano, A Inga, F Gemignani, S Landi
Oncogenesis 2 (7), e54-e54, 2013
Functional evolution of the p53 regulatory network through its target response elements
AG Jegga, A Inga, D Menendez, BJ Aronow, MA Resnick
Proceedings of the National Academy of Sciences 105 (3), 944-949, 2008
Tumour p53 mutations exhibit promoter selective dominance over wild type p53
P Monti, P Campomenosi, Y Ciribilli, R Iannone, A Inga, A Abbondandolo, ...
Oncogene 21 (11), 1641-1648, 2002
A functional genetic study identifies HAND1 mutations in septation defects of the human heart
SM Reamon-Buettner, Y Ciribilli, I Traverso, B Kuhls, A Inga, J Borlak
Human molecular genetics 18 (19), 3567-3578, 2009
A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1
D Menendez, A Inga, J Snipe, O Krysiak, G Schönfelder, MA Resnick
Molecular and cellular biology 27 (7), 2590-2600, 2007
Identification of new p53 target microRNAs by bioinformatics and functional analysis
A Bisio, V De Sanctis, V Del Vescovo, MA Denti, AG Jegga, A Inga, ...
BMC cancer 13 (1), 1-13, 2013
Discovery of a new small-molecule inhibitor of p53–MDM2 interaction using a yeast-based approach
M Leao, C Pereira, A Bisio, Y Ciribilli, AM Paiva, N Machado, A Palmeira, ...
Biochemical pharmacology 85 (9), 1234-1245, 2013
Altered-function p53 missense mutations identified in breast cancers can have subtle effects on transactivation
JJ Jordan, A Inga, K Conway, S Edmiston, LA Carey, L Wu, MA Resnick
Molecular cancer research 8 (5), 701-716, 2010
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