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Rachael Natrajan
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Resistance to therapy caused by intragenic deletion in BRCA2
SL Edwards, R Brough, CJ Lord, R Natrajan, R Vatcheva, DA Levine, ...
Nature 451 (7182), 1111-1115, 2008
10692008
Complex landscapes of somatic rearrangement in human breast cancer genomes
PJ Stephens, DJ McBride, ML Lin, I Varela, ED Pleasance, JT Simpson, ...
Nature 462 (7276), 1005-1010, 2009
9892009
BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells
G Molyneux, FC Geyer, FA Magnay, A McCarthy, H Kendrick, R Natrajan, ...
Cell stem cell 7 (3), 403-417, 2010
8722010
FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer
N Turner, A Pearson, R Sharpe, M Lambros, F Geyer, MA Lopez-Garcia, ...
Cancer research 70 (5), 2085-2094, 2010
7912010
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
SA Eccles, EO Aboagye, S Ali, AS Anderson, J Armes, F Berditchevski, ...
Breast Cancer Research 15 (5), 1-37, 2013
4952013
Breast cancer molecular profiling with single sample predictors: a retrospective analysis
B Weigelt, A Mackay, R A'hern, R Natrajan, DSP Tan, M Dowsett, ...
The lancet oncology 11 (4), 339-349, 2010
4692010
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets
N Turner, MB Lambros, HM Horlings, A Pearson, R Sharpe, R Natrajan, ...
Oncogene 29 (14), 2013-2023, 2010
4442010
β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation
FC Geyer, M Lacroix-Triki, K Savage, M Arnedos, MB Lambros, A MacKay, ...
Modern pathology 24 (2), 209-231, 2011
4082011
PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors
KJ Dedes, D Wetterskog, AM Mendes-Pereira, R Natrajan, MB Lambros, ...
Science translational medicine 2 (53), 53ra75-53ra75, 2010
3962010
Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer
DR Robinson, S Kalyana-Sundaram, YM Wu, S Shankar, X Cao, B Ateeq, ...
Nature medicine 17 (12), 1646-1651, 2011
3912011
Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity
I Bajrami, JR Frankum, A Konde, RE Miller, FL Rehman, R Brough, ...
Cancer research 74 (1), 287-297, 2014
3542014
Identification of a disease-defining gene fusion in epithelioid hemangioendothelioma
MR Tanas, A Sboner, AM Oliveira, MR Erickson-Johnson, J Hespelt, ...
Science translational medicine 3 (98), 98ra82-98ra82, 2011
3462011
Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C
NH Dryden, LR Broome, F Dudbridge, N Johnson, N Orr, S Schoenfelder, ...
Genome research 24 (11), 1854-1868, 2014
2652014
SF3B1 mutations constitute a novel therapeutic target in breast cancer
SL Maguire, A Leonidou, P Wai, C Marchiò, CKY Ng, A Sapino, ...
The Journal of pathology 235 (4), 571-580, 2015
2292015
Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas
FC Geyer, B Weigelt, R Natrajan, MBK Lambros, D de Biase, R Vatcheva, ...
The Journal of Pathology: A Journal of the Pathological Society of Great …, 2010
2292010
Genomic and mutational profiling of ductal carcinomas in situ and matched adjacent invasive breast cancers reveals intra‐tumour genetic heterogeneity and clonal …
L Hernandez, PM Wilkerson, MB Lambros, A Campion‐Flora, ...
The Journal of pathology 227 (1), 42-52, 2012
1922012
Mucinous carcinoma of the breast is genomically distinct from invasive ductal carcinomas of no special type
M Lacroix‐Triki, PH Suarez, A MacKay, MB Lambros, R Natrajan, ...
The Journal of pathology 222 (3), 282-298, 2010
1912010
FGFR Signaling Promotes the Growth of Triple-Negative and Basal-Like Breast Cancer Cell Lines Both In Vitro and In Vivo
R Sharpe, A Pearson, MT Herrera-Abreu, D Johnson, A Mackay, JC Welti, ...
Clinical Cancer Research 17 (16), 5275-5286, 2011
1902011
Down-regulation of the miRNA master regulators Drosha and Dicer is associated with specific subgroups of breast cancer
KJ Dedes, R Natrajan, MB Lambros, FC Geyer, MA Lopez-Garcia, ...
European journal of cancer 47 (1), 138-150, 2011
1862011
Tiling path genomic profiling of grade 3 invasive ductal breast cancers
R Natrajan, MB Lambros, SM Rodríguez-Pinilla, G Moreno-Bueno, ...
Clinical cancer research 15 (8), 2711-2722, 2009
1862009
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