Francois Vigneault
Francois Vigneault
CSO founder AbVitro, VP Research Juno, research fellow harvard University George Church lab
Potvrđena adresa e-pošte na
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes
JNH Stern, G Yaari, JA Vander Heiden, G Church, WF Donahue, ...
Science translational medicine 6 (248), 248ra107-248ra107, 2014
Reprogramming of T cells from human peripheral blood
YH Loh, O Hartung, H Li, C Guo, JM Sahalie, PD Manos, A Urbach, ...
Cell stem cell 7 (1), 15-19, 2010
pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires
JA Vander Heiden, G Yaari, M Uduman, JNH Stern, KC O’connor, ...
Bioinformatics 30 (13), 1930-1932, 2014
High-throughput single cell barcoding
GM Church, F Vigneault
US Patent 9,902,950, 2018
The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies
D Sok, U Laserson, J Laserson, Y Liu, F Vigneault, JP Julien, B Briney, ...
PLoS pathogens 9 (11), e1003754, 2013
Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data
G Yaari, JA Vander Heiden, M Uduman, D Gadala-Maria, N Gupta, ...
Frontiers in immunology 4, 358, 2013
Massively parallel sequencing of single cells by epicPCR links functional genes with phylogenetic markers
SJ Spencer, MV Tamminen, SP Preheim, MT Guo, AW Briggs, IL Brito, ...
The ISME journal 10 (2), 427-436, 2016
High-resolution antibody dynamics of vaccine-induced immune responses
U Laserson, F Vigneault, D Gadala-Maria, G Yaari, M Uduman, ...
Proceedings of the National Academy of Sciences 111 (13), 4928-4933, 2014
Single cell bar-coding for antibody discovery
F Vigneault, AW BRIGGS
US Patent 9,816,088, 2017
Salmonella infection drives promiscuous B cell activation followed by extrafollicular affinity maturation
R Di Niro, SJ Lee, JA Vander Heiden, RA Elsner, N Trivedi, JM Bannock, ...
Immunity 43 (1), 120-131, 2015
Systematic identification of edited microRNAs in the human brain
S Alon, E Mor, F Vigneault, GM Church, F Locatelli, F Galeano, A Gallo, ...
Genome research 22 (8), 1533-1540, 2012
Enzymatic oligonucleotide pre-adenylation
GM Church, F Vigneault, M Sismour
US Patent App. 12/533,304, 2010
Barcoding bias in high-throughput multiplex sequencing of miRNA
S Alon, F Vigneault, S Eminaga, DC Christodoulou, JG Seidman, ...
Genome research 21 (9), 1506-1511, 2011
Hierarchical clustering can identify B cell clones with high confidence in Ig repertoire sequencing data
NT Gupta, KD Adams, AW Briggs, SC Timberlake, F Vigneault, ...
The Journal of Immunology 198 (6), 2489-2499, 2017
Dysregulation of B cell repertoire formation in myasthenia gravis patients revealed through deep sequencing
JA Vander Heiden, P Stathopoulos, JQ Zhou, L Chen, TJ Gilbert, ...
The Journal of Immunology 198 (4), 1460-1473, 2017
High-throughput nucleotide library sequencing
F Vigneault, AW Briggs, CR Clouser, SJ Goldfless, S Timberlake
US Patent 10,590,483, 2020
Efficient microRNA capture and bar-coding via enzymatic oligonucleotide adenylation
F Vigneault, AM Sismour, GM Church
Nature methods 5 (9), 777-779, 2008
Methods of selecting T cell receptors using affinity oligonucleotide conjugates
F Vigneault, AW Briggs, SJ Goldfless, BJ Belmont
US Patent 10,393,743, 2019
Quantification of microRNA expression with next‐generation sequencing
S Eminaga, DC Christodoulou, F Vigneault, GM Church, JG Seidman
Current protocols in molecular biology 103 (1), 4.17. 1-4.17. 14, 2013
Transcriptional profiling of CD4 T cells identifies distinct subgroups of HIV-1 elite controllers
F Vigneault, M Woods, MJ Buzon, C Li, F Pereyra, SD Crosby, J Rychert, ...
Journal of virology 85 (6), 3015-3019, 2011
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