| Augmented IFN-γ and TNF-α induced by probiotic bacteria in NK cells mediate differentiation of stem-like tumors leading to inhibition of tumor growth and reduction in … VT Bui, HC Tseng, A Kozlowska, PO Maung, K Kaur, P Topchyan, ... Frontiers in immunology 6, 576, 2015 | 92 | 2015 |
| Novel strategy to expand super-charged NK cells with significant potential to lyse and differentiate cancer stem cells: differences in NK expansion and function between healthy … K Kaur, J Cook, SH Park, P Topchyan, A Kozlowska, N Ohanian, C Fang, ... Frontiers in immunology 8, 297, 2017 | 73 | 2017 |
| Differentiation by NK cells is a prerequisite for effective targeting of cancer stem cells/poorly differentiated tumors by chemopreventive and chemotherapeutic drugs AK Kozlowska, P Topchyan, K Kaur, HC Tseng, A Teruel, T Hiraga, ... Journal of Cancer 8 (4), 537, 2017 | 72 | 2017 |
| Super-charged NK cells inhibit growth and progression of stem-like/poorly differentiated oral tumors in vivo in humanized BLT mice; effect on tumor differentiation … K Kaur, P Topchyan, AK Kozlowska, N Ohanian, J Chiang, PO Maung, ... OncoImmunology 7 (5), e1426518, 2018 | 68 | 2018 |
| Resistance to cytotoxicity and sustained release of interleukin-6 and interleukin-8 in the presence of decreased interferon-γ after differentiation of glioblastoma by human … AK Kozlowska, HC Tseng, K Kaur, P Topchyan, A Inagaki, VT Bui, ... Cancer Immunology, Immunotherapy 65 (9), 1085-1097, 2016 | 65 | 2016 |
| Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection R Zander, MY Kasmani, Y Chen, P Topchyan, J Shen, S Zheng, R Burns, ... Immunity 55 (3), 475-493. e5, 2022 | 58 | 2022 |
| Probiotic-treated super-charged NK cells efficiently clear poorly differentiated pancreatic tumors in Hu-BLT mice K Kaur, AK Kozlowska, P Topchyan, MW Ko, N Ohanian, J Chiang, ... Cancers 12 (1), 63, 2019 | 49 | 2019 |
| Adoptive transfer of osteoclast-expanded natural killer cells for immunotherapy targeting cancer stem-like cells in humanized mice AK Kozlowska, K Kaur, P Topchyan, A Jewett Cancer Immunology, Immunotherapy 65 (7), 835-845, 2016 | 41 | 2016 |
| Deficiencies in natural killer cell numbers, expansion, and function at the pre-neoplastic stage of pancreatic cancer by KRAS mutation in the pancreas of obese mice K Kaur, HH Chang, P Topchyan, JM Cook, A Barkhordarian, G Eibl, ... Frontiers in immunology 9, 1229, 2018 | 38 | 2018 |
| Potent inhibition of tumour cell proliferation and immunoregulatory function by mitochondria-targeted atovaquone G Cheng, M Hardy, P Topchyan, R Zander, P Volberding, W Cui, ... Scientific reports 10 (1), 1-14, 2020 | 37 | 2020 |
| Novel strategies to target cancer stem cells by NK cells; studies in humanized mice AK Kozlowska, K Kaur, P Topchyan, A Jewett Frontiers in Bioscience-Landmark 22 (2), 370-384, 2017 | 32 | 2017 |
| Differential cytotoxicity but augmented IFN-γ secretion by NK cells after interaction with monocytes from humans, and those from wild type and myeloid specific COX-2 knockout mice HC Tseng, A Arasteh, K Kaur, A Kozlowska, P Topchyan, A Jewett Frontiers in immunology 6, 259, 2015 | 30 | 2015 |
| Clonal lineage tracing reveals mechanisms skewing CD8+ T cell fate decisions in chronic infection MY Kasmani, R Zander, HK Chung, Y Chen, A Khatun, M Damo, ... Journal of Experimental Medicine 220 (1), e20220679, 2022 | 29 | 2022 |
| Tumor Derived Extracellular Vesicles Drive T Cell Exhaustion in Tumor Microenvironment through Sphingosine Mediated Signaling and Impacting Immunotherapy Outcomes in Ovarian Cancer P Gupta, IP Kadamberi, S Mittal, SW Tsaih, J George, S Kumar, ... Advanced Science, 2104452, 2022 | 26 | 2022 |
| Targeting PIM1-mediated metabolism in myeloid suppressor cells to treat cancer G Xin, Y Chen, P Topchyan, MY Kasmani, R Burns, PJ Volberding, X Wu, ... Cancer immunology research 9 (4), 454-469, 2021 | 26 | 2021 |
| Single-Cell Transcriptomics Reveals Core Regulatory Programs That Determine the Heterogeneity of Circulating and Tissue-Resident Memory CD8+ T Cells Y Chen, J Shen, MY Kasmani, P Topchyan, W Cui Cells 10 (8), 2143, 2021 | 24 | 2021 |
| Harnessing the IL-21-BATF Pathway in the CD8+ T Cell Anti-Tumor Response P Topchyan, G Xin, Y Chen, S Zheng, R Burns, J Shen, MY Kasmani, ... Cancers 13 (6), 1263, 2021 | 20 | 2021 |
| Pathogen-Boosted Adoptive Cell Transfer Therapy Induces Endogenous Antitumor Immunity through Antigen SpreadingReACT Overcomes Antigen Escape G Xin, A Khatun, P Topchyan, R Zander, PJ Volberding, Y Chen, J Shen, ... Cancer immunology research 8 (1), 7-18, 2020 | 20 | 2020 |
| Mitochondria-targeted hydroxyurea inhibits OXPHOS and induces antiproliferative and immunomodulatory effects G Cheng, M Hardy, P Topchyan, R Zander, P Volberding, W Cui, ... iScience 24 (6), 102673, 2021 | 17 | 2021 |
| Spatial transcriptomics demonstrates the role of CD4 T cells in effector CD8 T cell differentiation during chronic viral infection P Topchyan, R Zander, MY Kasmani, C Nguyen, A Brown, S Lin, R Burns, ... Cell Reports 41 (9), 111736, 2022 | 8 | 2022 |
