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Zhu Dan
Zhu Dan
Verified email at utoronto.ca
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PKA activation bypasses the requirement for UNC-31 in the docking of dense core vesicles from C. elegans neurons
Zhou KM, Dong YM, Ge Q, Zhu D, Zhou W, Lin XG, Liang T, Wu ZX, Xu T
Neuron Nov 21 56 (4), 657-69, 2007
1032007
Dual role of VAMP8 in regulating insulin exocytosis and islet β cell growth
D Zhu, Y Zhang, PPL Lam, S Dolai, Y Liu, EP Cai, D Choi, SA Schroer, ...
Cell metabolism 16 (2), 238-249, 2012
922012
Characterization of zinc influx transporters (ZIPs) in pancreatic β cells: roles in regulating cytosolic zinc homeostasis and insulin secretion
Y Liu, B Batchuluun, L Ho, D Zhu, KJ Prentice, A Bhattacharjee, M Zhang, ...
Journal of Biological Chemistry 290 (30), 18757-18769, 2015
852015
In vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule trafficking
EP Cai, M Casimir, SA Schroer, CT Luk, SY Shi, D Choi, XQ Dai, ...
Diabetes 61 (7), 1708-1718, 2012
812012
Syntaxin-3 regulates newcomer insulin granule exocytosis and compound fusion in pancreatic beta cells
D Zhu, E Koo, E Kwan, Y Kang, S Park, H Xie, S Sugita, HY Gaisano
Diabetologia 56, 359-369, 2013
782013
Synaptotagmin-7 functions to replenish insulin granules for exocytosis in human islet β-cells
S Dolai, L Xie, D Zhu, T Liang, T Qin, H Xie, Y Kang, ER Chapman, ...
Diabetes 65 (7), 1962-1976, 2016
642016
Munc18b is a major mediator of insulin exocytosis in rat pancreatic β-cells
PPL Lam, M Ohno, S Dolai, Y He, T Qin, T Liang, D Zhu, Y Kang, Y Liu, ...
Diabetes 62 (7), 2416-2428, 2013
602013
Synaptotagmin I and IX function redundantly in controlling fusion pore of large dense core vesicles
D Zhu, W Zhou, T Liang, F Yang, RY Zhang, ZX Wu, T Xu
Biochemical and biophysical research communications 361 (4), 922-927, 2007
472007
New roles of syntaxin-1A in insulin granule exocytosis and replenishment
T Liang, T Qin, L Xie, S Dolai, D Zhu, KJ Prentice, M Wheeler, Y Kang, ...
Journal of biological chemistry 292 (6), 2203-2216, 2017
442017
Munc18c mediates exocytosis of pre-docked and newcomer insulin granules underlying biphasic glucose stimulated insulin secretion in human pancreatic beta-cells
D Zhu, L Xie, N Karimian, T Liang, Y Kang, YC Huang, HY Gaisano
Molecular metabolism 4 (5), 418-426, 2015
412015
Syntaxin-4 mediates exocytosis of pre-docked and newcomer insulin granules underlying biphasic glucose-stimulated insulin secretion in human pancreatic beta cells
L Xie, D Zhu, S Dolai, T Liang, T Qin, Y Kang, H Xie, YC Huang, ...
Diabetologia 58, 1250-1259, 2015
402015
Role of vesicle-associated membrane protein 2 in exocytosis of glucagon-like peptide-1 from the murine intestinal L cell
SK Li, D Zhu, HY Gaisano, PL Brubaker
Diabetologia 57, 809-818, 2014
392014
Differential Properties of GTP‐and Ca2+‐Stimulated Exocytosis from Large Dense Core Vesicles
Li Bai, Dan Zhu, Keming Zhou, Wei Zhou, Dongdong Li, Yan Wang, Rongying ...
Traffic 7 (4), 416–428, 2006
322006
A novel GLP1 receptor interacting protein ATP6ap2 regulates insulin secretion in pancreatic beta cells
FF Dai, A Bhattacharjee, Y Liu, B Batchuluun, M Zhang, XS Wang, ...
Journal of Biological Chemistry 290 (41), 25045-25061, 2015
312015
Role of mammalian homologue of Caenorhabditis elegans unc-13-1 (Munc13-1) in the recruitment of newcomer insulin granules in both first and second phases of …
L Xie, D Zhu, HY Gaisano
Diabetologia 55, 2693-2702, 2012
252012
Kv2. 1 clusters on β-cell plasma membrane act as reservoirs that replenish pools of newcomer insulin granule through their interaction with syntaxin-3
D Greitzer-Antes, L Xie, T Qin, H Xie, D Zhu, S Dolai, T Liang, F Kang, ...
Journal of Biological Chemistry 293 (18), 6893-6904, 2018
242018
Syntaxin 2 acts as inhibitory SNARE for insulin granule exocytosis
D Zhu, L Xie, Y Kang, S Dolai, J Bondo Hansen, T Qin, H Xie, T Liang, ...
Diabetes 66 (4), 948-959, 2017
242017
C2 domains of Munc13-4 are crucial for Ca2+-dependent degranulation and cytotoxicity in NK cells
NR Bin, K Ma, CW Tien, S Wang, D Zhu, S Park, E Turlova, K Sugita, ...
The Journal of Immunology 201 (2), 700-713, 2018
212018
Munc18b increases insulin granule fusion, restoring deficient insulin secretion in type-2 diabetes human and Goto-Kakizaki rat islets with improvement in glucose homeostasis
T Qin, T Liang, D Zhu, Y Kang, L Xie, S Dolai, S Sugita, N Takahashi, ...
EBioMedicine 16, 262-274, 2017
192017
SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes
T Liang, T Qin, F Kang, Y Kang, L Xie, D Zhu, S Dolai, D Greitzer-Antes, ...
JCI insight 5 (3), 2020
172020
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