| mTOR inhibitors in cancer therapy YY Zaytseva, JD Valentino, P Gulhati, BM Evers Cancer letters 319 (1), 1-7, 2012 | 364 | 2012 |
| An obligatory role for neurotensin in high-fat-diet-induced obesity J Li, J Song, YY Zaytseva, Y Liu, P Rychahou, K Jiang, ME Starr, JT Kim, ... Nature 533 (7603), 411-415, 2016 | 244 | 2016 |
| Adipocytes activate mitochondrial fatty acid oxidation and autophagy to promote tumor growth in colon cancer YA Wen, X Xing, JW Harris, YY Zaytseva, MI Mitov, DL Napier, HL Weiss, ... Cell death & disease 8 (2), e2593-e2593, 2017 | 219 | 2017 |
| Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer YY Zaytseva, PG Rychahou, P Gulhati, VA Elliott, WC Mustain, ... Cancer research 72 (6), 1504-1517, 2012 | 193 | 2012 |
| Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer YA Wen, X Xiong, YY Zaytseva, DL Napier, E Vallee, AT Li, C Wang, ... Cell death & disease 9 (3), 265, 2018 | 172 | 2018 |
| Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration YY Zaytseva, JW Harris, MI Mitov, JT Kim, DA Butterfield, EY Lee, ... Oncotarget 6 (22), 18891, 2015 | 128 | 2015 |
| Delivery of RNA nanoparticles into colorectal cancer metastases following systemic administration P Rychahou, F Haque, Y Shu, Y Zaytseva, HL Weiss, EY Lee, W Mustain, ... ACS nano 9 (2), 1108-1116, 2015 | 103 | 2015 |
| Cancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer YY Zaytseva, VA Elliott, P Rychahou, WC Mustain, JT Kim, J Valentino, ... Carcinogenesis 35 (6), 1341-1351, 2014 | 100 | 2014 |
| Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer YY Zaytseva, PG Rychahou, AT Le, TL Scott, RM Flight, JT Kim, J Harris, ... Oncotarget 9 (37), 24787, 2018 | 96 | 2018 |
| The PPARγ antagonist T0070907 suppresses breast cancer cell proliferation and motility via both PPARγ-dependent and-independent mechanisms YY Zaytseva, NK Wallis, RC Southard, MW Kilgore Anticancer research 31 (3), 813-823, 2011 | 80 | 2011 |
| Deptor is a novel target of Wnt/β-catenin/c-Myc and contributes to colorectal cancer cell growth Q Wang, Y Zhou, P Rychahou, JW Harris, YY Zaytseva, J Liu, C Wang, ... Cancer research 78 (12), 3163-3175, 2018 | 68 | 2018 |
| Inhibition of fatty acid synthase upregulates expression of CD36 to sustain proliferation of colorectal cancer cells J Drury, PG Rychahou, D He, N Jafari, C Wang, EY Lee, HL Weiss, ... Frontiers in Oncology 10, 1185, 2020 | 67 | 2020 |
| Cotargeting the PI3K and RAS pathways for the treatment of neuroendocrine tumors JD Valentino, J Li, YY Zaytseva, WC Mustain, VA Elliott, JT Kim, JW Harris, ... Clinical Cancer Research 20 (5), 1212-1222, 2014 | 66 | 2014 |
| Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression Y Guo, Q Ye, P Deng, Y Cao, D He, Z Zhou, C Wang, YY Zaytseva, ... Nature communications 11 (1), 3243, 2020 | 63 | 2020 |
| Colorectal cancer lung metastasis treatment with polymer–drug nanoparticles P Rychahou, Y Bae, D Reichel, YY Zaytseva, EY Lee, D Napier, HL Weiss, ... Journal of controlled release 275, 85-91, 2018 | 62 | 2018 |
| De Novo Fatty Acid Synthesis-Driven Sphingolipid Metabolism Promotes Metastatic Potential of Colorectal Cancer N Jafari, J Drury, AJ Morris, FO Onono, PD Stevens, T Gao, J Liu, C Wang, ... Molecular Cancer Research 17 (1), 140-152, 2019 | 59 | 2019 |
| Down-regulation of PPARgamma1 suppresses cell growth and induces apoptosis in MCF-7 breast cancer cells YY Zaytseva, X Wang, RC Southard, NK Wallis, MW Kilgore Molecular Cancer 7, 1-13, 2008 | 56 | 2008 |
| Upregulation of CPT1A is essential for the tumor-promoting effect of adipocytes in colon cancer X Xiong, YA Wen, R Fairchild, YY Zaytseva, HL Weiss, BM Evers, T Gao Cell death & disease 11 (9), 736, 2020 | 47 | 2020 |
| N-glycosylation-defective splice variants of neuropilin-1 promote metastasis by activating endosomal signals X Huang, Q Ye, M Chen, A Li, W Mi, Y Fang, YY Zaytseva, KL O’Connor, ... Nature communications 10 (1), 3708, 2019 | 41 | 2019 |
| Activation of c-Met and upregulation of CD44 expression are associated with the metastatic phenotype in the colorectal cancer liver metastasis model VA Elliott, P Rychahou, YY Zaytseva, BM Evers PLoS One 9 (5), e97432, 2014 | 40 | 2014 |
