| Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide ES Fischer, K Böhm, JR Lydeard, H Yang, MB Stadler, S Cavadini, ... Nature 512 (7512), 49-53, 2014 | 952 | 2014 |
| Break-induced replication and telomerase-independent telomere maintenance require Pol32 JR Lydeard, S Jain, M Yamaguchi, JE Haber Nature 448 (7155), 820-823, 2007 | 579 | 2007 |
| Building and remodelling Cullin–RING E3 ubiquitin ligases JR Lydeard, BA Schulman, JW Harper EMBO reports 14 (12), 1050-1061, 2013 | 345 | 2013 |
| Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly JR Lydeard, Z Lipkin-Moore, YJ Sheu, B Stillman, PM Burgers, JE Haber Genes & development 24 (11), 1133-1144, 2010 | 219 | 2010 |
| Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8 DC Scott, VO Sviderskiy, JK Monda, JR Lydeard, SE Cho, JW Harper, ... Cell 157 (7), 1671-1684, 2014 | 194 | 2014 |
| A recombination execution checkpoint regulates the choice of homologous recombination pathway during DNA double-strand break repair S Jain, N Sugawara, J Lydeard, M Vaze, NT Le Gac, JE Haber Genes & development 23 (3), 291-303, 2009 | 166 | 2009 |
| A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability BC O'Connell, B Adamson, JR Lydeard, ME Sowa, A Ciccia, ... Molecular cell 40 (4), 645-657, 2010 | 129 | 2010 |
| Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes JK Monda, DC Scott, DJ Miller, J Lydeard, D King, JW Harper, EJ Bennett, ... Structure 21 (1), 42-53, 2013 | 125 | 2013 |
| Sgs1 and Exo1 Redundantly Inhibit Break-Induced Replication and De Novo Telomere Addition at Broken Chromosome Ends JR Lydeard, Z Lipkin-Moore, S Jain, VV Eapen, JE Haber PLoS genetics 6 (5), e1000973, 2010 | 100 | 2010 |
| Systematic proteomics of the VCP–UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis M Raman, M Sergeev, M Garnaas, JR Lydeard, EL Huttlin, W Goessling, ... Nature cell biology 17 (10), 1356-1369, 2015 | 99 | 2015 |
| Inhibitors for E3 ubiquitin ligases JR Lydeard, JW Harper Nature biotechnology 28 (7), 682-684, 2010 | 25 | 2010 |
| MKRN3 inhibits puberty onset via interaction with IGF2BP1 and regulation of hypothalamic plasticity L Naulé, A Mancini, SA Pereira, BM Gassaway, JR Lydeard, JC Magnotto, ... JCI insight 8 (8), 2023 | 6 | 2023 |
| Correction: Corrigendum: Systematic proteomics of the VCP–UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis M Raman, M Sergeev, M Garnaas, JR Lydeard, EL Huttlin, W Goessling, ... Nature Cell Biology 18 (3), 347-347, 2016 | 1 | 2016 |
| Structure of DDB1-CRBN bound to thalidomide: insights into CRL4 inhibition by small molecules E Fischer, K Boehm, JR Lydeard, H Yang, MB Stadler, S Cavadini, ... Nature, 2014 | | 2014 |
J.Wade HarperProfessor of Cell BiologyPotvrđena adresa e-pošte na hms.harvard.edu
