Prati
Brooke Bullock Lao
Brooke Bullock Lao
Pfizer
Potvrđena adresa e-pošte na nyu.edu
Naslov
Citirano
Citirano
Godina
Assessing helical protein interfaces for inhibitor design
BN Bullock, AL Jochim, PS Arora
Journal of the American Chemical Society 133 (36), 14220-14223, 2011
3412011
Rational design of topographical helix mimics as potent inhibitors of protein–protein interactions
BB Lao, K Drew, DA Guarracino, TF Brewer, DW Heindel, R Bonneau, ...
Journal of the American Chemical Society 136 (22), 7877-7888, 2014
1392014
In vivo modulation of hypoxia-inducible signaling by topographical helix mimetics
BB Lao, I Grishagin, H Mesallati, TF Brewer, BZ Olenyuk, PS Arora
Proceedings of the National Academy of Sciences 111 (21), 7531-7536, 2014
1192014
Protein domain mimetics as in vivo modulators of hypoxia-inducible factor signaling
S Kushal, BB Lao, LK Henchey, R Dubey, H Mesallati, NJ Traaseth, ...
Proceedings of the National Academy of Sciences 110 (39), 15602-15607, 2013
1112013
Historical changes in the distributions of invasive and endemic marine invertebrates are contrary to global warming predictions: the effects of decadal climate oscillations
TJ Hilbish, PM Brannock, KR Jones, AB Smith, BN Bullock, DS Wethey
Journal of Biogeography 37 (3), 423-431, 2010
962010
Targeting HPV16 E6-p300 interaction reactivates p53 and inhibits the tumorigenicity of HPV-positive head and neck squamous cell carcinoma
X Xie, L Piao, BN Bullock, A Smith, T Su, M Zhang, TN Teknos, PS Arora, ...
Oncogene 33 (8), 1037-1046, 2014
922014
Plucking the high hanging fruit: A systematic approach for targeting protein–protein interactions
M Raj, BN Bullock, PS Arora
Bioorganic & medicinal chemistry 21 (14), 4051-4057, 2013
832013
Adding diverse noncanonical backbones to rosetta: enabling peptidomimetic design
K Drew, PD Renfrew, TW Craven, GL Butterfoss, FC Chou, S Lyskov, ...
PLoS One 8 (7), e67051, 2013
732013
Guest-accelerated molecular rotor
BE Dial, RD Rasberry, BN Bullock, MD Smith, PJ Pellechia, S Profeta Jr, ...
Organic Letters 13 (2), 244-247, 2011
412011
Protein–protein interactions in transcription: A fertile ground for helix mimetics
DA Guarracino, BN Bullock, PS Arora
Biopolymers 95 (1), 1-7, 2011
402011
A small molecule diacid with long-term chiral memory
RD Rasberry, X Wu, BN Bullock, MD Smith, KD Shimizu
Organic letters 11 (12), 2599-2602, 2009
322009
Oligooxopiperazines and methods of making and using them
PS Arora, P Tosovska, D Guarracino, B Bullock
US Patent 8,791,121, 2014
92014
Oligooxopiperazines and methods of making and using them
PS Arora, P To, D Guarracino, BB Lao
US Patent 9,309,230, 2016
72016
Oxopiperazine helix mimetics as inhibitors of the p53-MDM2 interaction
PS Arora, BB Lao, D Guarracino, R Bonneau, K Drew
US Patent 11,180,481, 2021
52021
Oligooxopiperazines and methods of making and using them
PS Arora, P To, D Guarracino, BB Lao
US Patent 9,624,203, 2017
42017
Control of hypoxia-inducible gene expression with oligooxopiperazine nonpeptidic helix mimetics
PS Arora, BB Lao
US Patent 9,783,526, 2017
32017
Oxopiperazine helix mimetics for control of Hypoxia-Inducible gene expression
PS Arora, BB Lao, R Bonneau, K Drew
US Patent 10,787,424, 2020
12020
Oligooxopiperazines as topographical helix mimetics
BB Lao, PS Arora
Peptidomimetics II, 1-24, 2017
12017
Hydrogen bond surrogate (HBS) helices as orthosteric regulator of hypoxia inducible transcription
S Kushal, B Bullock, L Henchey, P Arora, B Olenyuk
Cancer Research 72 (8_Supplement), 289-289, 2012
12012
Oxopiperazine helix mimetics for control of hypoxia-inducible gene expression
PS Arora, BB Lao, R Bonneau, K Drew
US Patent 11,560,359, 2023
2023
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