| Induction and repair of zinc-finger nuclease-targeted double-strand breaks in Caenorhabditis elegans somatic cells J Morton, MW Davis, EM Jorgensen, D Carroll Proceedings of the National Academy of Sciences 103 (44), 16370-16375, 2006 | 251 | 2006 |
| Design, construction and in vitro testing of zinc finger nucleases D Carroll, JJ Morton, KJ Beumer, DJ Segal Nature protocols 1 (3), 1329-1341, 2006 | 251 | 2006 |
| Humanized mouse xenograft models: narrowing the tumor–microenvironment gap JJ Morton, G Bird, Y Refaeli, A Jimeno Cancer research 76 (21), 6153-6158, 2016 | 250 | 2016 |
| A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins SB Keysar, DP Astling, RT Anderson, BW Vogler, DW Bowles, JJ Morton, ... Molecular oncology 7 (4), 776-790, 2013 | 171 | 2013 |
| Gene Activation Using FLP Recombinase in C. elegans MW Davis, JJ Morton, D Carroll, EM Jorgensen PLoS genetics 4 (3), e1000028, 2008 | 150 | 2008 |
| XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer JJ Morton, G Bird, SB Keysar, DP Astling, TR Lyons, RT Anderson, ... Oncogene 35 (3), 290-300, 2016 | 133 | 2016 |
| Cancer cell CD44 mediates macrophage/monocyte-driven regulation of head and neck cancer stem cells KE Gomez, FL Wu, SB Keysar, JJ Morton, B Miller, TS Chimed, PN Le, ... Cancer research 80 (19), 4185-4198, 2020 | 121 | 2020 |
| Regulation of head and neck squamous cancer stem cells by PI3K and SOX2 SB Keysar, PN Le, B Miller, BC Jackson, JR Eagles, C Nieto, J Kim, ... Journal of the National Cancer Institute 109 (1), djw189, 2017 | 121 | 2017 |
| Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer SB Keysar, PN Le, RT Anderson, JJ Morton, DW Bowles, JJ Paylor, ... Cancer research 73 (11), 3381-3392, 2013 | 104 | 2013 |
| Zinc-finger directed double-strand breaks within CAG repeat tracts promote repeat instability in human cells D Mittelman, C Moye, J Morton, K Sykoudis, Y Lin, D Carroll, JH Wilson Proceedings of the National Academy of Sciences 106 (24), 9607-9612, 2009 | 103 | 2009 |
| Hedgehog signaling drives radioresistance and stroma-driven tumor repopulation in head and neck squamous cancers GN Gan, J Eagles, SB Keysar, G Wang, MJ Glogowska, C Altunbas, ... Cancer research 74 (23), 7024-7036, 2014 | 72 | 2014 |
| Gene Targeting in Drosophila and Caenorhabditis elegans With Zinc-Finger Nucleases D Carroll, KJ Beumer, JJ Morton, A Bozas, JK Trautman Chromosomal Mutagenesis, 63-77, 2008 | 67 | 2008 |
| The transcription start site landscape of C. elegans TL Saito, S Hashimoto, SG Gu, JJ Morton, M Stadler, T Blumenthal, A Fire, ... Genome research 23 (8), 1348-1361, 2013 | 63 | 2013 |
| Wnt signaling dynamics in head and neck squamous cell cancer tumor‐stroma interactions PN Le, SB Keysar, B Miller, JR Eagles, TS Chimed, J Reisinger, ... Molecular carcinogenesis 58 (3), 398-410, 2019 | 56 | 2019 |
| The dual pathway inhibitor rigosertib is effective in direct patient tumor xenografts of head and neck squamous cell carcinomas RT Anderson, SB Keysar, DW Bowles, MJ Glogowska, DP Astling, ... Molecular cancer therapeutics 12 (10), 1994-2005, 2013 | 36 | 2013 |
| Salivary gland cancer patient-derived xenografts enable characterization of cancer stem cells and new gene events associated with tumor progression SB Keysar, JR Eagles, B Miller, BC Jackson, FN Chowdhury, J Reisinger, ... Clinical Cancer Research 24 (12), 2935-2943, 2018 | 30 | 2018 |
| Generation of functional human thymic cells from induced pluripotent stem cells HA Ramos, S.A., Morton, J.J., Yadav, P., Reed, B., Alizadeh, S.I., Shilleh ... J Allergy Clin Immunol, 2021 | 24* | 2021 |
| Dual use of hematopoietic and mesenchymal stem cells enhances engraftment and immune cell trafficking in an allogeneic humanized mouse model of head and neck cancer JJ Morton, SB Keysar, L Perrenoud, TS Chimed, J Reisinger, B Jackson, ... Molecular carcinogenesis 57 (11), 1651-1663, 2018 | 22 | 2018 |
| Expansion of Human and Murine Hematopoietic Stem and Progenitor Cells Ex Vivo without Genetic Modification Using MYC and Bcl-2 Fusion Proteins GA Bird, A Polsky, P Estes, T Hanlon, H Hamilton, JJ Morton, J Gutman, ... PloS one 9 (8), e105525, 2014 | 22 | 2014 |
| The humanized mouse: Emerging translational potential JJ Morton, N Alzofon, A Jimeno Molecular Carcinogenesis 59 (7), 830-838, 2020 | 21 | 2020 |
