m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways HB Li, J Tong, S Zhu, PJ Batista, EE Duffy, J Zhao, W Bailis, G Cao, ... Nature 548 (7667), 338-342, 2017 | 753 | 2017 |
KLRG1+ effector CD8+ T cells lose KLRG1, differentiate into all memory T cell lineages, and convey enhanced protective immunity D Herndler-Brandstetter, H Ishigame, R Shinnakasu, V Plajer, C Stecher, ... Immunity 48 (4), 716-729. e8, 2018 | 376 | 2018 |
Inflammasome activation in infected macrophages drives COVID-19 pathology E Sefik, R Qu, C Junqueira, E Kaffe, H Mirza, J Zhao, JR Brewer, A Han, ... Nature 606 (7914), 585-593, 2022 | 347 | 2022 |
Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells S Zhu, S Ding, P Wang, Z Wei, W Pan, NW Palm, Y Yang, H Yu, HB Li, ... Nature 546 (7660), 667-670, 2017 | 314 | 2017 |
Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche M Roulis, A Kaklamanos, M Schernthanner, P Bielecki, J Zhao, E Kaffe, ... Nature 580 (7804), 524-529, 2020 | 226 | 2020 |
Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function W Bailis, JA Shyer, J Zhao, JCG Canaveras, FJ Al Khazal, R Qu, ... Nature 571 (7765), 403-407, 2019 | 189 | 2019 |
Enteric nervous system-derived IL-18 orchestrates mucosal barrier immunity A Jarret, R Jackson, C Duizer, ME Healy, J Zhao, JM Rone, P Bielecki, ... Cell 180 (1), 50-63. e12, 2020 | 164 | 2020 |
Removal of batch effects using distribution-matching residual networks U Shaham, KP Stanton, J Zhao, H Li, K Raddassi, R Montgomery, ... Bioinformatics 33 (16), 2539-2546, 2017 | 164 | 2017 |
The DNA methylcytosine dioxygenase Tet2 sustains immunosuppressive function of tumor-infiltrating myeloid cells to promote melanoma progression W Pan, S Zhu, K Qu, K Meeth, J Cheng, K He, H Ma, Y Liao, X Wen, ... Immunity 47 (2), 284-297. e5, 2017 | 141 | 2017 |
Effector TH17 cells give rise to long-lived TRM cells that are essential for an immediate response against bacterial infection MCA Vesely, P Pallis, P Bielecki, JS Low, J Zhao, CCD Harman, ... Cell 178 (5), 1176-1188. e15, 2019 | 134 | 2019 |
Zero-preserving imputation of single-cell RNA-seq data GC Linderman, J Zhao, M Roulis, P Bielecki, RA Flavell, B Nadler, ... Nature communications 13 (1), 192, 2022 | 128 | 2022 |
Zero-preserving imputation of scRNA-seq data using low-rank approximation GC Linderman, J Zhao, Y Kluger BioRxiv, 397588, 2018 | 108 | 2018 |
Detection of differentially abundant cell subpopulations in scRNA-seq data J Zhao, A Jaffe, H Li, O Lindenbaum, E Sefik, R Jackson, X Cheng, ... Proceedings of the National Academy of Sciences 118 (22), e2100293118, 2021 | 90 | 2021 |
A humanized mouse model of chronic COVID-19 E Sefik, B Israelow, H Mirza, J Zhao, R Qu, E Kaffe, E Song, S Halene, ... Nature biotechnology 40 (6), 906-920, 2022 | 82 | 2022 |
A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies Y Song, A Rongvaux, A Taylor, T Jiang, T Tebaldi, K Balasubramanian, ... Nature communications 10 (1), 366, 2019 | 78 | 2019 |
m6A mRNA modification maintains colonic epithelial cell homeostasis via NF-κB–mediated antiapoptotic pathway T Zhang, C Ding, H Chen, J Zhao, Z Chen, B Chen, K Mao, Y Hao, ... Science Advances 8 (12), eabl5723, 2022 | 41 | 2022 |
The induction and function of the anti-inflammatory fate of TH17 cells H Xu, T Agalioti, J Zhao, B Steglich, R Wahib, MCA Vesely, P Bielecki, ... Nature Communications 11 (1), 3334, 2020 | 32 | 2020 |
Cyclin-dependent kinase 1 activity is a driver of cyst growth in polycystic kidney disease C Zhang, B Balbo, M Ma, J Zhao, X Tian, Y Kluger, S Somlo Journal of the American Society of Nephrology 32 (1), 41-51, 2021 | 30 | 2021 |
HIV viral transcription and immune perturbations in the CNS of people with HIV despite ART SF Farhadian, O Lindenbaum, J Zhao, MJ Corley, Y Im, H Walsh, ... JCI insight 7 (13), 2022 | 19 | 2022 |
A humanized mouse model of chronic COVID-19 to evaluate disease mechanisms and treatment options E Sefik, B Israelow, J Zhao, R Qu, E Song, H Mirza, E Kaffe, S Halene, ... Research Square, 2021 | 15 | 2021 |