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Leyden Fernandez
Leyden Fernandez
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Enterotypes of the human gut microbiome
M Arumugam, J Raes, E Pelletier, D Le Paslier, T Yamada, DR Mende, ...
nature 473 (7346), 174-180, 2011
80892011
Genetic algorithm optimization in drug design QSAR: Bayesian-regularized genetic neural networks (BRGNN) and genetic algorithm-optimized support vectors machines (GA-SVM)
M Fernandez, J Caballero, L Fernandez, A Sarai
Molecular diversity 15, 269-289, 2011
1192011
Amino Acid Sequence Autocorrelation vectors and ensembles of Bayesian-Regularized Genetic Neural Networks for prediction of conformational stability of human lysozyme mutants
J Caballero, L Fernández, JI Abreu, M Fernández
Journal of chemical information and modeling 46 (3), 1255-1268, 2006
702006
Proteometric study of ghrelin receptor function variations upon mutations using amino acid sequence autocorrelation vectors and genetic algorithm-based least square support …
J Caballero, L Fernández, M Garriga, JI Abreu, S Collina, M Fernández
Journal of Molecular Graphics and Modelling 26 (1), 166-178, 2007
682007
Amino acid sequence autocorrelation vectors and Bayesian‐regularized genetic neural networks for modeling protein conformational stability: Gene V protein mutants
L Fernández, J Caballero, JI Abreu, M Fernández
Proteins: Structure, Function, and Bioinformatics 67 (4), 834-852, 2007
572007
Identification of a potent and selective σ1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells
D Rossi, A Pedrali, M Urbano, R Gaggeri, M Serra, L Fernández, ...
Bioorganic & medicinal chemistry 19 (21), 6210-6224, 2011
562011
Tuning fresh: radiation through rewiring of central metabolism in streamlined bacteria
A Eiler, R Mondav, L Sinclair, L Fernandez-Vidal, DG Scofield, ...
The ISME journal 10 (8), 1902-1914, 2016
552016
Comprehensive dataset of shotgun metagenomes from oxygen stratified freshwater lakes and ponds
M Buck, SL Garcia, L Fernandez, G Martin, GA Martinez-Rodriguez, ...
Scientific Data 8 (1), 131, 2021
492021
Thermal stabilization of trypsin with glycol chitosan
L Fernández, L Gómez, HL Ramírez, ML Villalonga, R Villalonga
Journal of Molecular Catalysis B: Enzymatic 34 (1-6), 14-17, 2005
312005
Classification of conformational stability of protein mutants from 3D pseudo‐folding graph representation of protein sequences using support vector machines
M Fernández, J Caballero, L Fernández, JI Abreu, G Acosta
Proteins: Structure, Function, and Bioinformatics 70 (1), 167-175, 2008
292008
Protein radial distribution function (P-RDF) and Bayesian-Regularized Genetic Neural Networks for modeling protein conformational stability: Chymotrypsin inhibitor 2 mutants
M Fernández, J Caballero, L Fernández, JI Abreu, M Garriga
Journal of Molecular Graphics and Modelling 26 (4), 748-759, 2007
292007
Chemical glycosidation of trypsin with O‐carboxymethyl‐poly‐β‐cyclodextrin: catalytic and stability properties
ML Villalonga, G Reyes, A Fragoso, R Cao, L Fernández, R Villalonga
Biotechnology and applied biochemistry 41 (3), 217-223, 2005
262005
Adaptation to environmental factors shapes the organization of regulatory regions in microbial communities
L Fernandez, JM Mercader, M Planas-Fèlix, D Torrents
BMC genomics 15, 1-12, 2014
192014
Non‐cyanobacterial diazotrophs dominate nitrogen‐fixing communities in permafrost thaw ponds
L Fernandez, S Bertilsson, S Peura
Limnology and Oceanography 65, S180-S193, 2020
162020
Glycosidation of trypsin with end-group activated dextran
K Hernández, L Fernández, L Gómez, R Villalonga
Process Biochemistry 41 (5), 1155-1159, 2006
112006
Diazotroph genomes and their seasonal dynamics in a stratified humic bog lake
L Fernandez, S Peura, A Eiler, AM Linz, KD McMahon, S Bertilsson
Frontiers in Microbiology 11, 505352, 2020
82020
Comparative modeling of the conformational stability of chymotrypsin inhibitor 2 protein mutants using amino acid sequence autocorrelation (AASA) and amino acid 3D …
M Fernández, JI Abreu, J Caballero, M Garriga, L Fernández
Molecular Simulation 33 (13), 1045-1056, 2007
82007
Proteometric modelling of protein conformational stability using amino acid sequence autocorrelation vectors and genetic algorithm-optimised support vector machines
M Fernandez, L Fernandez, P Sanchez, J Caballero, JI Abreu
Molecular Simulation 34 (9), 857-872, 2008
72008
Proteochemometric Modeling of the Inhibition Complexes of Matrix Metalloproteinases with N‐Hydroxy‐2‐[(Phenylsulfonyl)Amino]Acetamide Derivatives Using …
M Fernández, L Fernández, J Caballero, JI Abreu, G Reyes
Chemical biology & drug design 72 (1), 65-78, 2008
72008
Classification of voltage-gated K+ ion channels from 3D pseudo-folding graph representation of protein sequences using genetic algorithm-optimized support vector machines
M Fernández, L Fernández, JI Abreu, M Garriga
Journal of Molecular Graphics and Modelling 26 (8), 1306-1314, 2008
72008
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