|Generation of human induced pluripotent stem cells from dermal fibroblasts|
WE Lowry, L Richter, R Yachechko, AD Pyle, J Tchieu, R Sridharan, ...
Proceedings of the National Academy of Sciences 105 (8), 2883-2888, 2008
|Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures|
MH Chin, MJ Mason, W Xie, S Volinia, M Singer, C Peterson, ...
Cell stem cell 5 (1), 111-123, 2009
|Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner|
JE Le Belle, NM Orozco, AA Paucar, JP Saxe, J Mottahedeh, AD Pyle, ...
Cell stem cell 8 (1), 59-71, 2011
|Defining the role of Wnt/β‐catenin signaling in the survival, proliferation, and self‐renewal of human embryonic stem cells|
G Dravid, Z Ye, H Hammond, G Chen, A Pyle, P Donovan, X Yu, L Cheng
Stem cells 23 (10), 1489-1501, 2005
|A single CRISPR-Cas9 deletion strategy that targets the majority of DMD patients restores dystrophin function in hiPSC-derived muscle cells|
CS Young, MR Hicks, NV Ermolova, H Nakano, M Jan, S Younesi, ...
Cell stem cell 18 (4), 533-540, 2016
|Neurotrophins mediate human embryonic stem cell survival|
AD Pyle, LF Lock, PJ Donovan
Nature biotechnology 24 (3), 344-350, 2006
|Female human iPSCs retain an inactive X chromosome|
J Tchieu, E Kuoy, MH Chin, H Trinh, M Patterson, SP Sherman, ...
Cell stem cell 7 (3), 329-342, 2010
|Specific loss of histone H3 lysine 9 trimethylation and HP1γ/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD)|
W Zeng, JC De Greef, YY Chen, R Chien, X Kong, HC Gregson, ...
PLoS genetics 5 (7), e1000559, 2009
|BRCA2 deficiency in mice leads to meiotic impairment and infertility|
SK Sharan, A Pyle, V Coppola, J Babus, S Swaminathan, J Benedict, ...
Oxford University Press for The Company of Biologists Limited 131 (1), 131-142, 2004
|Evidence for meiotic spindle checkpoint from analysis of spermatocytes from Robertsonian-chromosome heterozygous mice|
S Eaker, A Pyle, J Cobb, MA Handel
Journal of Cell Science 114 (16), 2953-2965, 2001
|Increased lysis of stem cells but not their differentiated cells by natural killer cells; de-differentiation or reprogramming activates NK cells|
HC Tseng, A Arasteh, A Paranjpe, A Teruel, W Yang, A Behel, JA Alva, ...
PloS one 5 (7), e11590, 2010
|Involvement of lysosomal exocytosis in the excretion of mesoporous silica nanoparticles and enhancement of the drug delivery effect by exocytosis inhibition|
RE Yanes, D Tarn, AA Hwang, DP Ferris, SP Sherman, CR Thomas, J Lu, ...
Small 9 (5), 697-704, 2013
|ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs|
MR Hicks, J Hiserodt, K Paras, W Fujiwara, A Eskin, M Jan, H Xi, ...
Nature cell biology 20 (1), 46-57, 2018
|Meiotic prophase abnormalities and metaphase cell death in MLH1-deficient mouse spermatocytes: insights into regulation of spermatogenic progress|
S Eaker, J Cobb, A Pyle, MA Handel
Developmental biology 249 (1), 85-95, 2002
|In vivo human somitogenesis guides somite development from hPSCs|
H Xi, W Fujiwara, K Gonzalez, M Jan, S Liebscher, B Van Handel, ...
Cell reports 18 (6), 1573-1585, 2017
|Nucleofection mediates high-efficiency stable gene knockdown and transgene expression in human embryonic stem cells|
KA Hohenstein, AD Pyle, JY Chern, LF Lock, PJ Donovan
Stem cells 26 (6), 1436-1443, 2008
|Creation of a novel humanized dystrophic mouse model of duchenne muscular dystrophy and application of a CRISPR/Cas9 gene editing therapy|
CS Young, E Mokhonova, M Quinonez, AD Pyle, MJ Spencer
Journal of neuromuscular diseases 4 (2), 139-145, 2017
|Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status|
JP Awe, PC Lee, C Ramathal, A Vega-Crespo, J Durruthy-Durruthy, ...
Stem cell research & therapy 4 (4), 1-15, 2013
|A human skeletal muscle atlas identifies the trajectories of stem and progenitor cells across development and from human pluripotent stem cells|
H Xi, J Langerman, S Sabri, P Chien, CS Young, S Younesi, M Hicks, ...
Cell stem cell 27 (1), 158-176. e10, 2020
|Copy number variant analysis of human embryonic stem cells|
H Wu, KJ Kim, K Mehta, S Paxia, A Sundstrom, T Anantharaman, ...
Stem Cells 26 (6), 1484-1489, 2008