Daniela Schuster
Daniela Schuster
Professor and Head of the Department of Pharmaceutical and Medicinal Chemistry at the Paracelsus
Potvrđena adresa e-pošte na - Početna stranica
Discovery and resupply of pharmacologically active plant-derived natural products: A review
AG Atanasov, B Waltenberger, EM Pferschy-Wenzig, T Linder, ...
Biotechnology advances 33 (8), 1582-1614, 2015
Natural products in drug discovery: Advances and opportunities
AG Atanasov, SB Zotchev, VM Dirsch, CT Supuran
Nature reviews Drug discovery 20 (3), 200-216, 2021
Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review
L Wang, B Waltenberger, EM Pferschy-Wenzig, M Blunder, X Liu, ...
Biochemical pharmacology 92 (1), 73-89, 2014
Why drugs fail-a study on side effects in new chemical entities
D Schuster, C Laggner, T Langer
Current pharmaceutical design 11 (27), 3545-3559, 2005
How to optimize shape-based virtual screening: choosing the right query and including chemical information
J Kirchmair, S Distinto, P Markt, D Schuster, GM Spitzer, KR Liedl, ...
Journal of chemical information and modeling 49 (3), 678-692, 2009
Pharmacophore models and pharmacophore-based virtual screening: concepts and applications exemplified on hydroxysteroid dehydrogenases
T Kaserer, KR Beck, M Akram, A Odermatt, D Schuster
Molecules 20 (12), 22799-22832, 2015
The discovery of new 11β-hydroxysteroid dehydrogenase type 1 inhibitors by common feature pharmacophore modeling and virtual screening
D Schuster, EM Maurer, C Laggner, LG Nashev, T Wilckens, T Langer, ...
Journal of medicinal chemistry 49 (12), 3454-3466, 2006
Honokiol: a non-adipogenic PPARγ agonist from nature
AG Atanasov, JN Wang, SP Gu, J Bu, MP Kramer, L Baumgartner, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1830 (10), 4813-4819, 2013
In silico target fishing for rationalized ligand discovery exemplified on constituents of Ruta graveolens
JM Rollinger, D Schuster, B Danzl, S Schwaiger, P Markt, M Schmidtke, ...
Planta medica 75 (03), 195-204, 2009
Parallel screening: a novel concept in pharmacophore modeling and virtual screening
TM Steindl, D Schuster, C Laggner, T Langer
Journal of chemical information and modeling 46 (5), 2146-2157, 2006
The Protein Data Bank (PDB), its related services and software tools as key components for in silico guided drug discovery
J Kirchmair, P Markt, S Distinto, D Schuster, GM Spitzer, KR Liedl, ...
Journal of medicinal chemistry 51 (22), 7021-7040, 2008
Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase
H Pein, A Ville, S Pace, V Temml, U Garscha, M Raasch, K Alsabil, ...
Nature communications 9 (1), 3834, 2018
Pharmacophore modeling and in silico screening for new P450 19 (aromatase) inhibitors
D Schuster, C Laggner, TM Steindl, A Palusczak, RW Hartmann, T Langer
Journal of chemical information and modeling 46 (3), 1301-1311, 2006
Methods for generating and applying pharmacophore models as virtual screening filters and for bioactivity profiling
A Vuorinen, D Schuster
Methods 71, 113-134, 2015
Enhancing drug discovery through in silico screening: strategies to increase true positives retrieval rates
J Kirchmair, S Distinto, D Schuster, G Spitzer, T Langer, G Wolber
Current medicinal chemistry 15 (20), 2040-2053, 2008
Structure-based virtual screening for the discovery of natural inhibitors for human rhinovirus coat protein
JM Rollinger, TM Steindl, D Schuster, J Kirchmair, K Anrain, EP Ellmerer, ...
Journal of medicinal chemistry 51 (4), 842-851, 2008
Why is 11β-hydroxysteroid dehydrogenase type 1 facing the endoplasmic reticulum lumen?: Physiological relevance of the membrane topology of 11β-HSD1
A Odermatt, AG Atanasov, Z Balazs, RAS Schweizer, LG Nashev, ...
Molecular and cellular endocrinology 248 (1-2), 15-23, 2006
Potent inhibition of human 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 by the anti-carcinogenic and anti-inflammatory agent embelin
AM Schaible, H Traber, V Temml, SM Noha, R Filosa, A Peduto, ...
Biochemical pharmacology 86 (4), 476-486, 2013
The identification of ligand features essential for PXR activation by pharmacophore modeling
D Schuster, T Langer
Journal of chemical information and modeling 45 (2), 431-439, 2005
The UV-filter benzophenone-1 inhibits 17β-hydroxysteroid dehydrogenase type 3: virtual screening as a strategy to identify potential endocrine disrupting chemicals
LG Nashev, D Schuster, C Laggner, S Sodha, T Langer, G Wolber, ...
Biochemical pharmacology 79 (8), 1189-1199, 2010
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