Swee Hoe Ong
Swee Hoe Ong
Wellcome Sanger Institute
Potvrđena adresa e-pošte na - Početna stranica
LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets
A Wilm, PPK Aw, D Bertrand, GHT Yeo, SH Ong, CH Wong, CC Khor, ...
Nucleic Acids Research, 2012
Spread, Circulation, and Evolution of the Middle East Respiratory Syndrome Coronavirus
M Cotten, SJ Watson, AI Zumla, HQ Makhdoom, AL Palser, SH Ong, ...
mBio 5 (1), e01062-13, 2014
IVA: accurate de novo assembly of RNA virus genomes
M Hunt, A Gall, SH Ong, J Brener, B Ferns, P Goulder, E Nastouli, ...
Bioinformatics 31 (14), 2374-2376, 2015
Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium
B Colom, MP Alcolea, G Piedrafita, MWJ Hall, A Wabik, SC Dentro, ...
Nature Genetics, 1-11, 2020
Mutant clones in normal epithelium outcompete and eliminate emerging tumours
B Colom, A Herms, MWJ Hall, SC Dentro, C King, RK Sood, MP Alcolea, ...
Nature 598 (7881), 510-514, 2021
Species Identification and Profiling of Complex Microbial Communities Using Shotgun Illumina Sequencing of 16S rRNA Amplicon Sequences
SH Ong, VU Kukkillaya, A Wilm, C Lay, EXP Ho, L Low, ML Hibberd, ...
PLOS ONE 8 (4), e60811, 2013
Genomic epidemiology of a dengue virus epidemic in urban Singapore
MJ Schreiber, EC Holmes, SH Ong, HSH Soh, W Liu, L Tanner, PPK Aw, ...
Journal of Virology 83 (9), 4163-4173, 2009
Outcompeting p53-mutant cells in the normal esophagus by redox manipulation
D Fernandez-Antoran, G Piedrafita, K Murai, SH Ong, A Herms, C Frezza, ...
Cell stem cell 25 (3), 329-341. e6, 2019
Deep sequencing of norovirus genomes defines evolutionary patterns in an urban tropical setting
M Cotten, V Petrova, MVT Phan, MA Rabaa, SJ Watson, SH Ong, ...
Journal of Virology 88 (19), 11056-11069, 2014
A method for full genome sequencing of all four serotypes of the dengue virus
JG Christenbury, PPK Aw, SH Ong, MJ Schreiber, A Chow, DJ Gubler, ...
Journal of Virological Methods 169 (1), 202-206, 2010
Epidermal tissue adapts to restrain progenitors carrying clonal p53 mutations
K Murai, G Skrupskelyte, G Piedrafita, M Hall, V Kostiou, SH Ong, T Nagy, ...
Cell stem cell 23 (5), 687-699. e8, 2018
Genome-wide CRISPR-KO Screen Uncovers mTORC1-Mediated Gsk3 Regulation in Naive Pluripotency Maintenance and Dissolution
M Li, SL Jason, K Tilgner, SH Ong, H Koike-Yusa, K Yusa
Cell Reports 24 (2), 489-502, 2018
Plasmablasts Generated during Repeated Dengue Infection Are Virus Glycoprotein–Specific and Bind to Multiple Virus Serotypes
MH Xu, V Hadinoto, R Appanna, K Joensson, YX Toh, T Balakrishnan, ...
The Journal of Immunology 189 (12), 5877-5885, 2012
Selection of oncogenic mutant clones in normal human skin varies with body site
JC Fowler, C King, C Bryant, MWJ Hall, R Sood, SH Ong, E Earp, ...
Cancer discovery 11 (2), 340-361, 2021
Easy and accurate reconstruction of whole HIV genomes from short-read sequence data with shiver
C Wymant, F Blanquart, T Golubchik, A Gall, M Bakker, D Bezemer, ...
Virus Evolution 4 (1), vey007, 2018
Periodic re-emergence of endemic strains with strong epidemic potential—A proposed explanation for the 2004 Indonesian dengue epidemic
SH Ong, JT Yip, YL Chen, W Liu, S Harun, E Lystiyaningsih, B Heriyanto, ...
Infection, Genetics and Evolution 8 (2), 191-204, 2008
Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe
F Blanquart, C Wymant, M Cornelissen, A Gall, M Bakker, D Bezemer, ...
PLoS biology 15 (6), e2001855, 2017
A highly virulent variant of HIV-1 circulating in the Netherlands
C Wymant, D Bezemer, F Blanquart, L Ferretti, A Gall, M Hall, T Golubchik, ...
Science 375 (6580), 540-545, 2022
Optimised metrics for CRISPR-KO screens with second-generation gRNA libraries
SH Ong, Y Li, H Koike-Yusa, K Yusa
Scientific Reports 7 (1), 7384, 2017
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth
E Abby, SC Dentro, MWJ Hall, JC Fowler, SH Ong, R Sood, A Herms, ...
Nature Genetics 55 (2), 232-245, 2023
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