Trevor M Darby
Trevor M Darby
Associate Academic Research Scientist - Emory University
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Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics
JY Li, B Chassaing, AM Tyagi, C Vaccaro, T Luo, J Adams, TM Darby, ...
The Journal of clinical investigation 126 (6), 2049-2063, 2016
Lactobacilli modulate epithelial cytoprotection through the Nrf2 pathway
RM Jones, C Desai, TM Darby, L Luo, AA Wolfarth, CD Scharer, CS Ardita, ...
Cell reports 12 (8), 1217-1225, 2015
Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis
S Yang, B Wang, F Humphries, R Jackson, ME Healy, R Bergin, G Aviello, ...
Nature immunology 14 (9), 927, 2013
Characterization of pro-inflammatory flagellin proteins produced by Lactobacillus ruminis and related motile lactobacilli
BA Neville, BM Forde, MJ Claesson, T Darby, A Coghlan, K Nally, ...
PLoS One 7 (7), 2012
The microbial metabolite butyrate stimulates bone formation via T regulatory cell-mediated regulation of WNT10B expression
AM Tyagi, M Yu, TM Darby, C Vaccaro, JY Li, JA Owens, E Hsu, J Adams, ...
Immunity 49 (6), 1116-1131. e7, 2018
Differential expression of key regulators of Toll‐like receptors in ulcerative colitis and Crohn's disease: a role for Tollip and peroxisome proliferator‐activated receptor gamma?
P Fernandes, J MacSharry, T Darby, A Fanning, F Shanahan, A Houston, ...
Clinical & Experimental Immunology 183 (3), 358-368, 2016
The complex role of inflammasomes in the pathogenesis of inflammatory bowel diseases–lessons learned from experimental models
M Aguilera, T Darby, S Melgar
Cytokine & growth factor reviews 25 (6), 715-730, 2014
A putative P-type ATPase required for virulence and resistance to haem toxicity in Listeria monocytogenes
HP McLaughlin, Q Xiao, RB Rea, H Pi, PG Casey, T Darby, A Charbit, ...
PloS one 7 (2), 2012
Cosmc is an X-linked inflammatory bowel disease risk gene that spatially regulates gut microbiota and contributes to sex-specific risk
MR Kudelka, BH Hinrichs, T Darby, CS Moreno, H Nishio, CE Cutler, ...
Proceedings of the National Academy of Sciences 113 (51), 14787-14792, 2016
Activation of liver X receptor suppresses the production of the IL-12 family of cytokines by blocking nuclear translocation of NF-κBp50
M Canavan, C McCarthy, NB Larbi, JK Dowling, L Collins, F O’Sullivan, ...
Innate immunity 20 (7), 675-687, 2014
Effects of anti-inflammatory therapy on bursting pressure of colonic anastomosis in murine dextran sulfate sodium induced colitis
P Myrelid, SY Salim, T Darby, S Almer, S Melgar, P Andersson, ...
Scandinavian journal of gastroenterology 50 (8), 991-1001, 2015
Lactobacilli modulate epithelial cytoprotection through the Nrf2 pathway. Cell Rep 12: 1217–1225
RM Jones, C Desai, TM Darby, L Luo, AA Wolfarth, CD Scharer, CS Ardita, ...
Proteomic analysis of microbial induced redox-dependent intestinal signaling
JD Matthews, AR Reedy, H Wu, BH Hinrichs, TM Darby, C Addis, ...
Redox biology 20, 526-532, 2019
Beneficial influences of Lactobacillus plantarum on human health and disease
TM Darby, RM Jones
The microbiota in gastrointestinal pathophysiology, 109-117, 2017
Lactococcus Lactis Subsp. cremoris Is an Efficacious Beneficial Bacterium that Limits Tissue Injury in the Intestine
TM Darby, JA Owens, BJ Saeedi, L Luo, JD Matthews, BS Robinson, ...
iScience 12, 356-367, 2019
Lactococcus Lactis subsp. cremoris Elicits Protection Against Metabolic Changes Induced by a Western-style Diet
CR Naudin, K Maner-Smith, JA Owens, GM Wynn, BS Robinson, ...
Gastroenterology, 2020
Regulation of oxidative liver injury by the probiotic Lactobacillus rhamnosus GG
BJ Saeedi, B Robinson, J Owens, K Liu, L Luo, T Darby, D Jones, ...
The FASEB Journal 32 (1_supplement), 150.4-150.4, 2018
Cell differentiation in the murine intestine requires NADPH oxidase 1
T Darby, R Jones
The FASEB Journal 30 (1_supplement), 57.3-57.3, 2016
Gut-Resident Lactobacilli Activate Hepatic Nrf2 and Protect Against Oxidative Liver Injury
BJ Saeedi, KH Liu, JA Owens, S Hunter-Chang, MC Camacho, RU Eboka, ...
Cell Metabolism, 2020
Lactobacillus rhamnosus GG-induced expression of Leptin in the intestine orchestrates epithelial cell proliferation
TM Darby, CR Naudin, L Luo, RM Jones
Cellular and Molecular Gastroenterology and Hepatology, 2019
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