Prati
Brandon B. Holmes
Brandon B. Holmes
Research and Clinical Fellow, UCSF
Potvrđena adresa e-pošte na ucsf.edu
Naslov
Citirano
Citirano
Godina
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
BB Holmes, SL DeVos, N Kfoury, M Li, R Jacks, K Yanamandra, ...
Proceedings of the National Academy of Sciences 110 (33), E3138-E3147, 2013
8642013
Trans-cellular propagation of Tau aggregation by fibrillar species
N Kfoury, BB Holmes, H Jiang, DM Holtzman, MI Diamond
Journal of Biological Chemistry 287 (23), 19440-19451, 2012
6442012
Proteopathic tau seeding predicts tauopathy in vivo
BB Holmes, JL Furman, TE Mahan, TR Yamasaki, H Mirbaha, WC Eades, ...
Proceedings of the National Academy of sciences 111 (41), E4376-E4385, 2014
5852014
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy
SL DeVos, RL Miller, KM Schoch, BB Holmes, CS Kebodeaux, ...
Science translational medicine 9 (374), eaag0481, 2017
4382017
In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice
K Yamada, JR Cirrito, FR Stewart, H Jiang, MB Finn, BB Holmes, ...
Journal of Neuroscience 31 (37), 13110-13117, 2011
3912011
Tau trimers are the minimal propagation unit spontaneously internalized to seed intracellular aggregation
H Mirbaha, BB Holmes, DW Sanders, J Bieschke, MI Diamond
Journal of biological chemistry 290 (24), 14893-14903, 2015
2392015
Prion-like Properties of Tau Protein: The Importance of Extracellular Tau as a Therapeutic Target
BB Holmes, MI Diamond
The Journal of Biological Chemistry 289 (29), 19855-19861, 2014
2212014
Parkinson’s disease and multiple system atrophy have distinct α-synuclein seed characteristics
TR Yamasaki, BB Holmes, JL Furman, DD Dhavale, BW Su, ES Song, ...
Journal of Biological Chemistry 294 (3), 1045-1058, 2019
1712019
Specific glycosaminoglycan chain length and sulfation patterns are required for cell uptake of tau versus α-synuclein and β-amyloid aggregates
BE Stopschinski, BB Holmes, GM Miller, VA Manon, J Vaquer-Alicea, ...
Journal of Biological Chemistry 293 (27), 10826-10840, 2018
1622018
An N-terminal nuclear export signal regulates trafficking and aggregation of Huntingtin (Htt) protein exon 1
Z Zheng, A Li, BB Holmes, JC Marasa, MI Diamond
Journal of Biological Chemistry 288 (9), 6063-6071, 2013
1002013
Prions and protein assemblies that convey biological information in health and disease
DW Sanders, SK Kaufman, BB Holmes, MI Diamond
Neuron 89 (3), 433-448, 2016
892016
Cellular mechanisms of protein aggregate propagation
BB Holmes, MI Diamond
Current opinion in neurology 25 (6), 721-726, 2012
842012
Sensitive detection of proteopathic seeding activity with FRET flow cytometry
JL Furman, BB Holmes, MI Diamond
JoVE (Journal of Visualized Experiments), e53205, 2015
822015
Macrophage migration inhibitory factor acts as a neurotrophin in the developing inner ear
LM Bank, LM Bianchi, F Ebisu, D Lerman-Sinkoff, EC Smiley, Y Shen, ...
Development 139 (24), 4666-4674, 2012
452012
Antibodies to tau
D Holtzman, H Jiang, M Diamond, N Kfoury, B Holmes
US Patent 9,834,596, 2017
282017
A synthetic heparinoid blocks Tau aggregate cell uptake and amplification
BE Stopschinski, TL Thomas, S Nadji, E Darvish, L Fan, BB Holmes, ...
Journal of Biological Chemistry 295 (10), 2974-2983, 2020
272020
Heparan sulfate proteoglycans mediate Aβ-induced oxidative stress and hypercontractility in cultured vascular smooth muscle cells
MR Reynolds, I Singh, TD Azad, BB Holmes, PB Verghese, HH Dietrich, ...
Molecular neurodegeneration 11, 1-15, 2016
272016
Cellular models for the study of prions
BB Holmes, MI Diamond
Cold Spring Harbor Perspectives in Medicine 7 (2), a024026, 2017
252017
Amyotrophic lateral sclerosis and organ donation: is there risk of disease transmission?
BB Holmes, MI Diamond
Annals of neurology 72 (6), 832-836, 2012
202012
Vertebrobasilar Dolichoectasia Causing An Optic Tract Syndrome
Holmes BB, Green WC, Kung NH, Goebel JA, Van Stavern GP
J Neuroophthalmol 37 (2), 179-181, 2017
13*2017
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