Prati
Nicholas J. Bradshaw
Nicholas J. Bradshaw
Department of Biotechnology, University of Rijeka, Croatia
Potvrđena adresa e-pošte na biotech.uniri.hr
Naslov
Citirano
Citirano
Godina
The DISC locus in psychiatric illness
JE Chubb, NJ Bradshaw, DC Soares, DJ Porteous, JK Millar
Molecular psychiatry 13 (1), 36-64, 2008
7112008
DISC1-binding proteins in neural development, signalling and schizophrenia
NJ Bradshaw, DJ Porteous
Neuropharmacology 62 (3), 1230-1241, 2012
2422012
DISC1: structure, function, and therapeutic potential for major mental illness
DC Soares, BC Carlyle, NJ Bradshaw, DJ Porteous
ACS chemical neuroscience 2 (11), 609-632, 2011
1582011
DISC1, PDE4B, and NDE1 at the centrosome and synapse
NJ Bradshaw, F Ogawa, B Antolin-Fontes, JE Chubb, BC Carlyle, ...
Biochemical and biophysical research communications 377 (4), 1091-1096, 2008
1082008
PKA phosphorylation of NDE1 is DISC1/PDE4 dependent and modulates its interaction with LIS1 and NDEL1
NJ Bradshaw, DC Soares, BC Carlyle, F Ogawa, H Davidson-Smith, ...
Journal of Neuroscience 31 (24), 9043-9054, 2011
912011
A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious …
JE Eykelenboom, GJ Briggs, NJ Bradshaw, DC Soares, F Ogawa, ...
Human molecular genetics 21 (15), 3374-3386, 2012
842012
Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits
V Bader, L Tomppo, SV Trossbach, NJ Bradshaw, I Prikulis, SR Leliveld, ...
Human molecular genetics 21 (20), 4406-4418, 2012
822012
Recent and Recurrent Selective Sweeps of the Antiviral RNAi Gene Argonaute-2 in Three Species of Drosophila
DJ Obbard, FM Jiggins, NJ Bradshaw, TJ Little
Molecular biology and evolution 28 (2), 1043-1056, 2011
682011
NDE1 and NDEL1 from genes to (mal) functions: parallel but distinct roles impacting on neurodevelopmental disorders and psychiatric illness
NJ Bradshaw, MAF Hayashi
Cellular and molecular life sciences 74, 1191-1210, 2017
592017
NDE1 and NDEL1: twin neurodevelopmental proteins with similar ‘nature’but different ‘nurture’
NJ Bradshaw, W Hennah, DC Soares
Biomolecular concepts 4 (5), 447-464, 2013
582013
Protein misassembly and aggregation as potential convergence points for non-genetic causes of chronic mental illness
NJ Bradshaw, C Korth
Molecular psychiatry 24 (7), 936-951, 2019
572019
NDE1 and NDEL1: multimerisation, alternate splicing and DISC1 interaction
NJ Bradshaw, S Christie, DC Soares, BC Carlyle, DJ Porteous, JK Millar
Neuroscience letters 449 (3), 228-233, 2009
552009
Revisiting disrupted-in-schizophrenia 1 as a scaffold protein
ASK Yerabham, OH Weiergräber, NJ Bradshaw, C Korth
Biological chemistry 394 (11), 1425-1437, 2013
442013
The mitosis and neurodevelopment proteins NDE1 and NDEL1 form dimers, tetramers, and polymers with a folded back structure in solution
DC Soares, NJ Bradshaw, J Zou, CK Kennaway, RS Hamilton, ZA Chen, ...
Journal of Biological Chemistry 287 (39), 32381-32393, 2012
432012
Aggregation of the protein TRIOBP-1 and its potential relevance to schizophrenia
NJ Bradshaw, V Bader, I Prikulis, A Lueking, S Müllner, C Korth
PloS one 9 (10), e111196, 2014
372014
A structural organization for the Disrupted in Schizophrenia 1 protein, identified by high-throughput screening, reveals distinctly folded regions, which are bisected by mental …
ASK Yerabham, PJ Mas, C Decker, DC Soares, OH Weiergräber, ...
Journal of Biological Chemistry 292 (16), 6468-6477, 2017
242017
An unpredicted aggregation-critical region of the actin-polymerizing protein TRIOBP-1/Tara, determined by elucidation of its domain structure
NJ Bradshaw, ASK Yerabham, R Marreiros, T Zhang, L Nagel-Steger, ...
Journal of Biological Chemistry 292 (23), 9583-9598, 2017
232017
Loss of Reelin protects mice against arterial thrombosis by impairing integrin activation and thrombus formation under high shear conditions
NS Gowert, I Krüger, M Klier, L Donner, F Kipkeew, M Gliem, ...
Cellular Signalling 40, 210-221, 2017
192017
The TRIOBP isoforms and their distinct roles in actin stabilization, deafness, mental illness, and cancer
B Zaharija, B Samardžija, NJ Bradshaw
Molecules 25 (21), 4967, 2020
172020
The NDE1 genomic locus can affect treatment of psychiatric illness through gene expression changes related to microRNA-484
NJ Bradshaw, L Ukkola-Vuoti, M Pankakoski, AB Zheutlin, ...
Open biology 7 (11), 170153, 2017
172017
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