|Microglia development and function|
D Nayak, TL Roth, DB McGavern
Annual review of immunology 32, 367-402, 2014
|Inflammation and neuroprotection in traumatic brain injury|
KN Corps, TL Roth, DB McGavern
JAMA neurology 72 (3), 355-362, 2015
|Transcranial amelioration of inflammation and cell death after brain injury|
TL Roth, D Nayak, T Atanasijevic, AP Koretsky, LL Latour, DB McGavern
Nature 505 (7482), 223-228, 2014
|Reprogramming human T cell function and specificity with non-viral genome targeting|
TL Roth, C Puig-Saus, R Yu, E Shifrut, J Carnevale, PJ Li, J Hiatt, J Saco, ...
Nature 559 (7714), 405-409, 2018
|Discovery of stimulation-responsive immune enhancers with CRISPR activation|
DR Simeonov, BG Gowen, M Boontanrart, TL Roth, JD Gagnon, ...
Nature 549 (7670), 111-115, 2017
|Genome-wide CRISPR screens in primary human T cells reveal key regulators of immune function|
E Shifrut, J Carnevale, V Tobin, TL Roth, JM Woo, CT Bui, PJ Li, ...
Cell 175 (7), 1958-1971. e15, 2018
|Single-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1|
L Milenkovic, LE Weiss, J Yoon, TL Roth, YRS Su, SJ Sahl, MP Scott, ...
Proceedings of the National Academy of Sciences 112 (27), 8320-8325, 2015
|A SARS-CoV-2 protein interaction map reveals targets for drug repurposing|
DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ...
Nature, 1-13, 2020
|Type I interferon programs innate myeloid dynamics and gene expression in the virally infected nervous system|
D Nayak, KR Johnson, S Heydari, TL Roth, BH Zinselmeyer, ...
PLoS pathogens 9 (5), 2013
|Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node|
Y Zhang, TL Roth, EE Gray, H Chen, LB Rodda, Y Liang, P Ventura, ...
Elife 5, e18156, 2016
|Enhanced genome editing with Cas9 ribonucleoprotein in diverse cells and organisms|
B Farboud, E Jarvis, TL Roth, J Shin, JE Corn, A Marson, BJ Meyer, ...
JoVE (Journal of Visualized Experiments), e57350, 2018
|CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions|
JF Hultquist, J Hiatt, K Schumann, MJ McGregor, TL Roth, P Haas, ...
Nature protocols 14 (1), 1-27, 2019
|A rapid and simple method for DNA engineering using cycled ligation assembly|
TL Roth, L Milenkovic, MP Scott
PloS one 9 (9), 2014
|Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins|
CAM Wu, TL Roth, Y Baglaenko, DM Ferri, P Brauer, JC Zuniga-Pflucker, ...
Journal of immunological methods 457, 33-40, 2018
|Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency|
DN Nguyen, TL Roth, PJ Li, PA Chen, R Apathy, MR Mamedov, LT Vo, ...
Nature Biotechnology 38 (1), 44-49, 2020
|Light-activated cell identification and sorting (LACIS) for selection of edited clones on a nanofluidic device|
A Mocciaro, TL Roth, HM Bennett, M Soumillon, A Shah, J Hiatt, ...
Communications biology 1 (1), 1-8, 2018
|Large dataset enables prediction of repair after CRISPR–Cas9 editing in primary T cells|
RT Leenay, A Aghazadeh, J Hiatt, D Tse, TL Roth, R Apathy, E Shifrut, ...
Nature biotechnology 37 (9), 1034-1037, 2019
|A large CRISPR-induced bystander mutation causes immune dysregulation|
DR Simeonov, AJ Brandt, AY Chan, JT Cortez, Z Li, JM Woo, Y Lee, ...
Communications biology 2 (1), 1-6, 2019
|Orthotopic replacement of T-cell receptor α-and β-chains with preservation of near-physiological T-cell function|
K Schober, TR Müller, F Gökmen, S Grassmann, M Effenberger, ...
Nature biomedical engineering 3 (12), 974-984, 2019
|Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells|
MSF Ng, TL Roth, VF Mendoza, A Marson, TD Burt
Science immunology 4 (41), 2019