S. Hong Chan
mRNA capping: biological functions and applications
A Ramanathan, GB Robb, SH Chan
Nucleic acids research 44 (16), 7511-7526, 2016
Structural basis of RNA cap modification by SARS-CoV-2
T Viswanathan, S Arya, SH Chan, S Qi, N Dai, A Misra, JG Park, ...
Nature communications 11 (1), 3718, 2020
Natural and engineered nicking endonucleases—from cleavage mechanism to engineering of strand-specificity
SH Chan, BL Stoddard, S Xu
Nucleic acids research 39 (1), 1-18, 2011
A type IV modification-dependent restriction enzyme SauUSI from Staphylococcus aureus subsp. aureus USA300
S Xu, AR Corvaglia, SH Chan, Y Zheng, P Linder
Nucleic acids research 39 (13), 5597-5610, 2011
Trichosanthin interacts with acidic ribosomal proteins P0 and P1 and mitotic checkpoint protein MAD2B
SH Chan, FSJ Hung, DSB Chan, PC Shaw
European Journal of Biochemistry 268 (7), 2107-2112, 2001
Discovery of natural nicking endonucleases Nb. BsrDI and Nb. BtsI and engineering of top-strand nicking variants from BsrDI and BtsI
SY Xu, Z Zhu, P Zhang, SH Chan, JC Samuelson, J Xiao, D Ingalls, ...
Nucleic acids research 35 (14), 4608-4618, 2007
Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15I
YK Gupta, SH Chan, S Xu, AK Aggarwal
Nature Communications 6 (1), 7363, 2015
Cloning of CviPII nicking and modification system from chlorella virus NYs-1 and application of Nt. CviPII in random DNA amplification
S Chan, Z Zhu, JL Van Etten, S Xu
Nucleic acids research 32 (21), 6187-6199, 2004
Unusual target site disruption by the rare-cutting HNH restriction endonuclease PacI
BW Shen, DF Heiter, SH Chan, H Wang, SY Xu, RD Morgan, GG Wilson, ...
Structure 18 (6), 734-743, 2010
Engineering of a mini-trichosanthin that has lower antigenicity by deleting its C-terminal amino acid residues
SH Chan, PC Shaw, SFC Mulot, LH Xu, WL Chan, SC Tam, KB Wong
Biochemical and Biophysical Research Communications 270 (1), 279-285, 2000
Characterization and crystal structure of the type IIG restriction endonuclease RM. BpuSI
BW Shen, D Xu, SH Chan, Y Zheng, Z Zhu, S Xu, BL Stoddard
Nucleic acids research 39 (18), 8223-8236, 2011
Engineering BspQI nicking enzymes and application of N. BspQI in DNA labeling and production of single-strand DNA
P Zhang, PHM Too, JC Samuelson, SH Chan, T Vincze, S Doucette, ...
Protein expression and purification 69 (2), 226-234, 2010
Catalytic domain of restriction endonuclease BmrI as a cleavage module for engineering endonucleases with novel substrate specificities
S Chan, Y Bao, E Ciszak, S Laget, S Xu
Nucleic acids research 35 (18), 6238-6248, 2007
Crystal structure of the restriction-modification system control element C. BclI and mapping of its binding site
MR Sawaya, Z Zhu, F Mersha, S Chan, R Dabur, S Xu, GK Balendiran
Structure 13 (12), 1837-1847, 2005
A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2′-O methylation of its first nucleotide
T Viswanathan, A Misra, SH Chan, S Qi, N Dai, S Arya, ...
Nature communications 12 (1), 3287, 2021
Cofactor requirement of HpyAV restriction endonuclease
SH Chan, L Opitz, L Higgins, D O'loane, S Xu
PLoS One 5 (2), e9071, 2010
Cloning of Nt. CviQII nicking endonuclease and its cognate methyltransferase: M. CviQII methylates AG sequences
S Chan, Z Zhu, DD Dunigan, JL Van Etten, S Xu
Protein expression and purification 49 (1), 138-150, 2006
Expression and purification of BmrI restriction endonuclease and its N-terminal cleavage domain variants
Y Bao, L Higgins, P Zhang, S Chan, S Laget, S Sweeney, K Lunnen, S Xu
Protein expression and purification 58 (1), 42-52, 2008
Solution structure and thermal stability of ribosomal protein L30e from hyperthermophilic archaeon Thermococcus celer
KB Wong, CF Lee, SH Chan, TY Leung, YW Chen, M Bycroft
Protein science 12 (7), 1483-1495, 2003
Engineering Nt. BtsCI and Nb. BtsCI nicking enzymes and applications in generating long overhangs
PHM Too, Z Zhu, SH Chan, S Xu
Nucleic acids research 38 (4), 1294-1303, 2010
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