| The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome with 16,000 Tiny Chromosomes EC Swart, JR Bracht, V Magrini, P Minx, X Chen, Y Zhou, JS Khurana, ... PLoS biology 11 (1), e1001473, 2013 | 247 | 2013 |
| The architecture of a scrambled genome reveals massive levels of genomic rearrangement during development X Chen, JR Bracht, AD Goldman, E Dolzhenko, DM Clay, EC Swart, ... Cell 158 (5), 1187-1198, 2014 | 202 | 2014 |
| Spinal muscular atrophy diagnosis and carrier screening from genome sequencing data X Chen, A Sanchis-Juan, CE French, AJ Connell, I Delon, Z Kingsbury, ... Genetics in Medicine 22 (5), 945-953, 2020 | 123 | 2020 |
| The Physarum polycephalum Genome Reveals Extensive Use of Prokaryotic Two-Component and Metazoan-Type Tyrosine Kinase Signaling P Schaap, I Barrantes, P Minx, N Sasaki, RW Anderson, M Bénard, ... Genome biology and evolution 8 (1), 109-125, 2016 | 101 | 2016 |
| Cyrius: accurate CYP2D6 genotyping using whole genome sequencing data X Chen, F Shen, N Gonzaludo, A Malhotra, C Rogert, RJ Taft, DR Bentley, ... The Pharmacogenomics Journal, 1-11, 2021 | 71 | 2021 |
| Comprehensive SMN1 and SMN2 profiling for spinal muscular atrophy analysis using long-read PacBio HiFi sequencing X Chen, J Harting, E Farrow, I Thiffault, D Kasperaviciute, A Hoischen, ... The American Journal of Human Genetics 110 (2), 240-250, 2023 | 44 | 2023 |
| Depletion of p31comet protein promotes sensitivity to antimitotic drugs HT Ma, YY Chan, X Chen, KF On, RYC Poon Journal of Biological Chemistry 287 (25), 21561-21569, 2012 | 40 | 2012 |
| Comprehensive short and long read sequencing analysis for the Gaucher and Parkinson’s disease-associated GBA gene M Toffoli, X Chen, FJ Sedlazeck, CY Lee, S Mullin, A Higgins, S Koletsi, ... Communications Biology 5 (1), 670, 2022 | 35 | 2022 |
| Combinatorial DNA rearrangement facilitates the origin of new genes in ciliates X Chen, S Jung, LY Beh, SR Eddy, LF Landweber Genome biology and evolution 7 (10), 2859-2870, 2015 | 29 | 2015 |
| Transcription-independent functions of an RNA polymerase II subunit, Rpb2, during genome rearrangement in the ciliate, Oxytricha trifallax JS Khurana, X Wang, X Chen, DH Perlman, LF Landweber Genetics 197 (3), 839-849, 2014 | 28 | 2014 |
| Recurring patterns among scrambled genes in the encrypted genome of the ciliate Oxytricha trifallax J Burns, D Kukushkin, X Chen, LF Landweber, M Saito, N Jonoska Journal of Theoretical Biology 410, 171-180, 2016 | 26 | 2016 |
| Phylogenomic analysis reveals genome-wide purifying selection on TBE transposons in the ciliate Oxytricha X Chen, LF Landweber Mobile DNA 7, 1-10, 2016 | 18 | 2016 |
| The effect of SMN gene dosage on ALS risk and disease severity M Moisse, RAJ Zwamborn, J van Vugt, R van der Spek, W van Rheenen, ... Annals of Neurology, 2021 | 16 | 2021 |
| Comparative genomics reveals insight into the evolutionary origin of massively scrambled genomes Y Feng, R Neme, LY Beh, X Chen, J Braun, MW Lu, LF Landweber Elife 11, e82979, 2022 | 11 | 2022 |
| Chromosome fusions triggered by noncoding RNA JR Bracht, X Wang, K Shetty, X Chen, GJ Uttarotai, EC Callihan, ... RNA biology 14 (5), 620-631, 2017 | 10 | 2017 |
| < mds_ies_db>: a database of ciliate genome rearrangements J Burns, D Kukushkin, K Lindblad, X Chen, N Jonoska, LF Landweber Nucleic acids research 44 (D1), D703-D709, 2016 | 10 | 2016 |
| Identification of allele-specific KIV-2 repeats and impact on Lp (a) measurements for cardiovascular disease risk S Behera, JR Belyeu, X Chen, LF Paulin, NQH Nguyen, E Newman, ... BMC Medical Genomics 17 (1), 255, 2024 | 9 | 2024 |
| Intronic Haplotypes in the GBA Gene Do Not Predict Age at Diagnosis of Parkinson's Disease M Toffoli, A Higgins, C Lee, S Koletsi, X Chen, M Eberle, FJ Sedlazeck, ... Movement Disorders 36 (6), 1456-1460, 2021 | 6 | 2021 |
| HiFi long-read genomes for difficult-to-detect, clinically relevant variants W Höps, MM Weiss, R Derks, JC Galbany, A den Ouden, ... The American Journal of Human Genetics 112 (2), 450-456, 2025 | 2 | 2025 |
| Genome-wide profiling of highly similar paralogous genes using HiFi sequencing X Chen, D Baker, E Dolzhenko, JM Devaney, J Noya, AS Berlyoung, ... Nature Communications 16 (1), 1-13, 2025 | | 2025 |
