Daniel A Kraut
Daniel A Kraut
Professor & Chair of Chemistry, Villanova University
Potvrđena adresa e-pošte na - Početna stranica
Challenges in enzyme mechanism and energetics
DA Kraut, KS Carroll, D Herschlag
Annual review of biochemistry 72 (1), 517-571, 2003
Testing electrostatic complementarity in enzyme catalysis: hydrogen bonding in the ketosteroid isomerase oxyanion hole
DA Kraut, PA Sigala, B Pybus, CW Liu, D Ringe, GA Petsko, D Herschlag
PLoS biology 4 (4), e99, 2006
Disordered proteinaceous machines
M Fuxreiter, A Tóth-Petróczy, DA Kraut, AT Matouschek, RYH Lim, B Xue, ...
Chemical reviews 114 (13), 6806-6843, 2014
Testing geometrical discrimination within an enzyme active site: Constrained hydrogen bonding in the ketosteroid isomerase oxyanion hole
PA Sigala, DA Kraut, JMM Caaveiro, B Pybus, EA Ruben, D Ringe, ...
Journal of the American Chemical Society 130 (41), 13696-13708, 2008
ATP-dependent proteases differ substantially in their ability to unfold globular proteins
P Koodathingal, NE Jaffe, DA Kraut, S Prakash, S Fishbain, C Herman, ...
Journal of Biological Chemistry 284 (28), 18674-18684, 2009
Determining the catalytic role of remote substrate binding interactions in ketosteroid isomerase
JP Schwans, DA Kraut, D Herschlag
Proceedings of the National Academy of Sciences 106 (34), 14271-14275, 2009
Dissecting the paradoxical effects of hydrogen bond mutations in the ketosteroid isomerase oxyanion hole
DA Kraut, PA Sigala, TD Fenn, D Herschlag
Proceedings of the National Academy of Sciences 107 (5), 1960, 2010
Evaluating the potential for halogen bonding in the oxyanion hole of ketosteroid isomerase using unnatural amino acid mutagenesis
DA Kraut, MJ Churchill, PE Dawson, D Herschlag
ACS chemical biology 4 (4), 269-273, 2009
Sequence-and species-dependence of proteasomal processivity
DA Kraut, E Israeli, EK Schrader, A Patil, K Nakai, D Nanavati, T Inobe, ...
ACS chemical biology 7 (8), 1444-1453, 2012
Inactivation studies of acetylcholinesterase with phenylmethylsulfonyl fluoride
D Kraut, H Goff, RK Pai, NA Hosea, I Silman, JL Sussman, P Taylor, ...
Molecular pharmacology 57 (6), 1243, 2000
To degrade or release: ubiquitin-chain remodeling
DA Kraut, S Prakash, A Matouschek
Trends in cell biology 17 (9), 419-421, 2007
Substrate ubiquitination controls the unfolding ability of the proteasome
EL Reichard, GG Chirico, WJ Dewey, ND Nassif, KE Bard, NE Millas, ...
Journal of Biological Chemistry 291 (35), 18547-18561, 2016
Proteasomal Degradation from Internal Sites Favors Partial Proteolysis via Remote Domain Stabilization
DA Kraut, A Matouschek
ACS chemical biology 6 (10), 1087-1095, 2011
Slipping up: Partial substrate degradation by ATP‐dependent proteases
ND Nassif, SE Cambray, DA Kraut
IUBMB life 66 (5), 309-317, 2014
Ubiquitin receptors are required for substrate-mediated activation of the proteasome’s unfolding ability
MD Cundiff, CM Hurley, JD Wong, JA Boscia iV, A Bashyal, J Rosenberg, ...
Scientific Reports 9 (1), 14506, 2019
An integrated computational and experimental approach to identifying inhibitors for SARS-CoV-2 3CL protease
T Zhai, F Zhang, S Haider, D Kraut, Z Huang
Frontiers in molecular biosciences 8, 661424, 2021
Mode of targeting to the proteasome determines GFP fate
CE Bragança, DA Kraut
Journal of Biological Chemistry 295 (47), 15892-15901, 2020
Slippery substrates impair ATP-dependent protease function by slowing unfolding
DA Kraut
Journal of Biological Chemistry 288 (48), 34729-34735, 2013
Pup grows up: in vitro characterization of the degradation of pupylated proteins
DA Kraut, A Matouschek
The EMBO journal 29 (7), 1163-1164, 2010
Proteasomal conformation controls unfolding ability
JR Cresti, AJ Manfredonia, CE Bragança, JA Boscia IV, CM Hurley, ...
Proceedings of the National Academy of Sciences 118 (25), e2101004118, 2021
Sustav trenutno ne može provesti ovu radnju. Pokušajte ponovo kasnije.
Članci 1–20