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Stefan Oswald
Stefan Oswald
University Medicine of Greifswald, Department of Clinical Pharmacology
Verified email at uni-greifswald.de
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Membrane transporters in drug development
Nature reviews Drug discovery 9 (3), 215-236, 2010
34832010
Hepatic uptake of the magnetic resonance imaging contrast agent Gd-EOB-DTPA: role of human organic anion transporters
M Leonhardt, M Keiser, S Oswald, J Kühn, J Jia, M Grube, HK Kroemer, ...
Drug Metabolism and Disposition 38 (7), 1024-1028, 2010
2742010
Protein abundance of clinically relevant multidrug transporters along the entire length of the human intestine
M Drozdzik, C Gröer, J Penski, J Lapczuk, M Ostrowski, Y Lai, B Prasad, ...
Molecular pharmaceutics 11 (10), 3547-3555, 2014
2732014
Organic anion transporting polypeptide 2B1 is a high‐affinity transporter for atorvastatin and is expressed in the human heart
M Grube, K Köck, S Oswald, K Draber, K Meissner, L Eckel, M Böhm, ...
Clinical Pharmacology & Therapeutics 80 (6), 607-620, 2006
2552006
Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid–enhanced MR imaging
A Nassif, J Jia, M Keiser, S Oswald, C Modess, S Nagel, W Weitschies, ...
Radiology 264 (3), 741-750, 2012
1612012
LC–MS/MS-based quantification of clinically relevant intestinal uptake and efflux transporter proteins
C Gröer, S Brück, Y Lai, A Paulick, A Busemann, CD Heidecke, ...
Journal of pharmaceutical and biomedical analysis 85, 253-261, 2013
1532013
Chronic stress increases experimental pancreatic cancer growth, reduces survival and can be antagonised by beta-adrenergic receptor blockade
LI Partecke, S Speerforck, A Käding, F Seubert, S Kühn, E Lorenz, ...
Pancreatology 16 (3), 423-433, 2016
1312016
Protein abundance of clinically relevant drug‐metabolizing enzymes in the human liver and intestine: a comparative analysis in paired tissue specimens
M Drozdzik, D Busch, J Lapczuk, J Müller, M Ostrowski, M Kurzawski, ...
Clinical pharmacology & therapeutics 104 (3), 515-524, 2018
1272018
Intestinal expression of P‐glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate–glucuronosyltransferase 1A1 …
S Oswald, S Haenisch, C Fricke, T Sudhop, C Remmler, T Giessmann, ...
Clinical Pharmacology & Therapeutics 79 (3), 206-217, 2006
1212006
Protein abundance of clinically relevant drug transporters in the human liver and intestine: a comparative analysis in paired tissue specimens
M Drozdzik, D Busch, J Lapczuk, J Müller, M Ostrowski, M Kurzawski, ...
Clinical Pharmacology & Therapeutics 105 (5), 1204-1212, 2019
1122019
Variability in mass spectrometry-based quantification of clinically relevant drug transporters and drug metabolizing enzymes
C Wegler, FZ Gaugaz, TB Andersson, JR Wiśniewski, D Busch, C Gröer, ...
Molecular pharmaceutics 14 (9), 3142-3151, 2017
1112017
Disposition of ezetimibe is influenced by polymorphisms of the hepatic uptake carrier OATP1B1
S Oswald, J König, D Lütjohann, T Giessmann, HK Kroemer, C Rimmbach, ...
Pharmacogenetics and genomics 18 (7), 559-568, 2008
1102008
A LC–MS/MS method to quantify the novel cholesterol lowering drug ezetimibe in human serum, urine and feces in healthy subjects genotyped for SLCO1B1
S Oswald, E Scheuch, I Cascorbi, W Siegmund
Journal of Chromatography B 830 (1), 143-150, 2006
1042006
Absolute protein quantification of clinically relevant cytochrome P450 enzymes and UDP-glucuronosyltransferases by mass spectrometry-based targeted proteomics
C Gröer, D Busch, M Patrzyk, K Beyer, A Busemann, CD Heidecke, ...
Journal of pharmaceutical and biomedical analysis 100, 393-401, 2014
992014
Expression, regulation and function of intestinal drug transporters: an update
J Müller, M Keiser, M Drozdzik, S Oswald
Biological chemistry 398 (2), 175-192, 2017
912017
Human platelets express organic anion-transporting peptide 2B1, an uptake transporter for atorvastatin
J Niessen, G Jedlitschky, M Grube, S Bien, H Schwertz, S Ohtsuki, ...
Drug Metabolism and Disposition 37 (5), 1129-1137, 2009
752009
Caco‐2 cells–expression, regulation and function of drug transporters compared with human jejunal tissue
S Brück, J Strohmeier, D Busch, M Drozdzik, S Oswald
Biopharmaceutics & drug disposition 38 (2), 115-126, 2017
702017
Pharmaceutical excipients influence the function of human uptake transporting proteins
A Engel, S Oswald, W Siegmund, M Keiser
Molecular pharmaceutics 9 (9), 2577-2581, 2012
702012
Targeted adsorption of molecules in the colon with the novel adsorbent‐based Medicinal Product, DAV132: A proof of concept study in healthy subjects
J de Gunzburg, A Ducher, C Modess, D Wegner, S Oswald, J Dressman, ...
The Journal of Clinical Pharmacology 55 (1), 10-16, 2015
692015
Expression of clinically relevant drug‐metabolizing enzymes along the human intestine and their correlation to drug transporters and nuclear receptors: An intra‐subject analysis
A Fritz, D Busch, J Lapczuk, M Ostrowski, M Drozdzik, S Oswald
Basic & clinical pharmacology & toxicology 124 (3), 245-255, 2019
632019
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