The 90-kDa molecular chaperone family: structure, function, and clinical applications. A comprehensive review P Csermely, T Schnaider, C Soti, Z Prohászka, G Nardai Pharmacology & therapeutics 79 (2), 129-168, 1998 | 1429 | 1998 |
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila C Burnett, S Valentini, F Cabreiro, M Goss, M Somogyvári, MD Piper, ... nature 477 (7365), 482-485, 2011 | 766 | 2011 |
Heat shock proteins as emerging therapeutic targets C Sőti, E Nagy, Z Giricz, L Vígh, P Csermely, P Ferdinandy British journal of pharmacology 146 (6), 769-780, 2005 | 503 | 2005 |
A nucleotide-dependent molecular switch controls ATP binding at the C-terminal domain of Hsp90: N-terminal nucleotide binding unmasks a C-terminal binding pocket C Söti, A Rácz, P Csermely Journal of biological chemistry 277 (9), 7066-7075, 2002 | 322 | 2002 |
Aging and molecular chaperones C Soti, P Csermely Experimental gerontology 38 (10), 1037-1040, 2003 | 217 | 2003 |
Inhibition of Hsp90: a new strategy for inhibiting protein kinases AS Sreedhar, C Söti, P Csermely Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1697 (1-2), 233-242, 2004 | 205 | 2004 |
ATP induces a conformational change of the 90-kDa heat shock protein (hsp90). P Csermely, J Kajtár, M Hollosi, G Jalsovszky, S Holly, CR Kahn, ... Journal of Biological Chemistry 268 (3), 1901-1907, 1993 | 204 | 1993 |
The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer’s disease pathology: From antioxidant to epigenetic therapy C Grinan-Ferre, A Bellver-Sanchis, V Izquierdo, R Corpas, J Roig-Soriano, ... Ageing Research Reviews 67, 101271, 2021 | 182 | 2021 |
A role for SKN-1/Nrf in pathogen resistance and immunosenescence in Caenorhabditis elegans D Papp, P Csermely, C Sőti PLoS pathogens 8 (4), e1002673, 2012 | 169 | 2012 |
Molecular chaperones, stress proteins and redox homeostasis E Papp, G Nardai, C Söti, P Csermely Biofactors 17 (1‐4), 249-257, 2003 | 169 | 2003 |
Molecular chaperones and the aging process C Sőti, P Csermely Biogerontology 1 (3), 225-233, 2000 | 163 | 2000 |
Chaperones and aging: role in neurodegeneration and in other civilizational diseases C Söti, P Csermely Neurochemistry international 41 (6), 383-389, 2002 | 161 | 2002 |
Apoptosis, necrosis and cellular senescence: chaperone occupancy as a potential switch C Sőti, AS Sreedhar, P Csermely Aging cell 2 (1), 39-45, 2003 | 141 | 2003 |
Comparative analysis of the ATP‐binding sites of Hsp90 by nucleotide affinity cleavage: a distinct nucleotide specificity of the C‐terminal ATP‐binding site C So˝ ti, A Vermes, TAJ Haystead, P Csermely European journal of biochemistry 270 (11), 2421-2428, 2003 | 138 | 2003 |
Molecular chaperones as regulatory elements of cellular networks C Sőti, C Pál, B Papp, P Csermely Current opinion in cell biology 17 (2), 210-215, 2005 | 125 | 2005 |
Resveratrol induces the heat-shock response and protects human cells from severe heat stress A Putics, EM Vegh, P Csermely, C Sőti Antioxidants & redox signaling 10 (1), 65-76, 2008 | 111 | 2008 |
Expressed as the sole Hsp90 of yeast, the α and β isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90β … SH Millson, AW Truman, A Racz, B Hu, B Panaretou, J Nuttall, ... The FEBS journal 274 (17), 4453-4463, 2007 | 110 | 2007 |
Modelling the actions of chaperones and their role in ageing CJ Proctor, C Sőti, RJ Boys, CS Gillespie, DP Shanley, DJ Wilkinson, ... Mechanisms of ageing and development 126 (1), 119-131, 2005 | 103 | 2005 |
Chaperone function and chaperone overload in the aged. A preliminary analysis G Nardai, P Csermely, C Söti Experimental gerontology 37 (10-11), 1257-1262, 2002 | 103 | 2002 |
Protein stress and stress proteins: implications in aging and disease C Sőti, P Csermely Journal of biosciences 32, 511-515, 2007 | 91 | 2007 |